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Inhibitor Report for: ZTL-11

General
Type GSK-3 kinase inhibitor, Carboxamide, Multitarget, Triazol, Indole, Cyclopropyl, beta-carboline
Chemical_Nomenclature 1-(Cyclopropanecarboxamido)-N-((1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methyl)-9H-pyrido[3,4-b]indole-7-carboxamide
Canonical SMILES C14=C([N]C2=C1[C]=[C]N=C2[N]C(=O)[C]3CC3)[C]=C([C]=[C]4)C([N]CC5=[C][N](N=N5)CC6=[C][C]=[C][C]=C6F)=O
InChI InChI=1S/C26H22FN7O2/c27-21-4-2-1-3-17(21)13-34-14-18(32-33-34)12-29-25(35)16-7-8-19-20-9-10-28-24(23(20)30-22(19)11-16)31-26(36)15-5-6-15/h1-4,7-11,14-15,30H,5-6,12-13H2,(H,29,35)(H,28,31,36)
InChIKey YJUAZZHNQVXWDO-UHFFFAOYSA-N
Other name(s) ZTL-11
________________________________________________________________________________________________
MW|484.18
Formula|C26H22FN7O2
CAS_number|
PubChem|
UniChem|YJUAZZHNQVXWDO-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | ZTL-11 ligand of proteins in family: ACHE

References:
Search PubMed for references concerning: ZTL-11
    Title: Discovery of novel beta-carboline-1,2,3-triazole hybrids as AChE/GSK-3beta dual inhibitors for Alzheimer's disease treatment
    Liu W, Tian L, Wu L, Chen H, Wang N, Liu X, Zhao C, Wu Z, Jiang X and Zhao Q <2 more author(s)>
    Ref: Bioorg Chem, 129:106168, 2022 : PubMed