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Inhibitor Report for: Z-Pro-Prolinal-IC2

General
Type Benzyloxycarbonyl, Pyrrolidine, Peptide, Carboxamide
Chemical_Nomenclature (5R)-N-benzyl-5-[(2S)-2-[(1R)-1,2-dihydroxyethyl]pyrrolidine-1-carbonyl]cyclopentene-1-carboxamide
Canonical SMILES C1CC(N(C1)C(=O)C2CCC=C2C(=O)NCC3=CC=CC=C3)C(CO)O
InChI InChI=1S/C20H26N2O4/c23-13-18(24)17-10-5-11-22(17)20(26)16-9-4-8-15(16)19(25)21-12-14-6-2-1-3-7-14/h1-3,6-8,16-18,23-24H,4-5,9-13H2,(H,21,25)/t16-,17+,18+/m1/s1
InChIKey YWYIBAJVRQWUCG-SQNIBIBYSA-N
Other name(s) IC2 ; 2P4
________________________________________________________________________________________________
MW|358.43
Formula|C20H26N2O4
CAS_number|
PubChem|72200811
UniChem|YWYIBAJVRQWUCG-SQNIBIBYSA-N
IUPHAR|
Wikipedia|

Target
Families | Z-Pro-Prolinal-IC2 ligand of proteins in family: S9N_PPCE_Peptidase_S9
Stucture | 1 structure: 4AMZ: Prolyl Oligopeptidase from porcine brain with a covalently bound inhibitor IC-2
Protein | pig-ppce

References:
Search PubMed for references concerning: Z-Pro-Prolinal-IC2
    Title: Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase.
    Kaszuba K, Rog T, Danne R, Canning P, Fulop V, Juhasz T, Szeltner Z, St Pierre JF, Garcia-Horsman A and Bunker A <3 more author(s)>
    Ref: Biochimie, 94:1398, 2012 : PubMed