Tris(2-chloroethyl)-phosphate

Tris(2-chloroethyl) phosphate (TCEP) is a chemical compound used as a flame retardant, plasticizer, and viscosity regulator in various types of polymers including polyurethanes, polyester resins, and polyacrylates.

General

Type : Organophosphate,Organophosphorus flame retardant plasticizer

Chemical_Nomenclature : tris(2-chloroethyl) phosphate

Canonical SMILES : C(CCl)OP(=O)(OCCCl)OCCCl

InChI : InChI=1S\/C6H12Cl3O4P\/c7-1-4-11-14(10,12-5-2-8)13-6-3-9\/h1-6H2

InChIKey : HQUQLFOMPYWACS-UHFFFAOYSA-N

Other name(s) : Tri(beta-chloroethyl) phosphate,Tris(2-chloroethyl) orthophosphate,Tris(2-chloroethyl)-phosphate,Tris(2-chloroethyl)phosphate,TCEP


MW : 285.5

Formula : C6H12Cl3O4P

CAS_number : 115-96-8

PubChem : 8295

UniChem : HQUQLFOMPYWACS-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families :

Stucture :

Protein :

References (9)

Title : Similarities and differences among the responses to three chlorinated organophosphate esters in earthworm: Evidences from biomarkers, transcriptomics and metabolomics - Gao_2022_Sci.Total.Environ_815_152853
Author(s) : Gao Y , Wang L , Zhang X , Shi C , Ma L , Wang G
Ref : Sci Total Environ , 815 :152853 , 2022
Abstract : Gao_2022_Sci.Total.Environ_815_152853
ESTHER : Gao_2022_Sci.Total.Environ_815_152853
PubMedSearch : Gao_2022_Sci.Total.Environ_815_152853
PubMedID: 34998776

Title : The adverse effect of TCIPP and TCEP on neurodevelopment of zebrafish embryos\/larvae - Li_2019_Chemosphere_220_811
Author(s) : Li R , Wang H , Mi C , Feng C , Zhang L , Yang L , Zhou B
Ref : Chemosphere , 220 :811 , 2019
Abstract : Li_2019_Chemosphere_220_811
ESTHER : Li_2019_Chemosphere_220_811
PubMedSearch : Li_2019_Chemosphere_220_811
PubMedID: 30612050

Title : Intestinal damage, neurotoxicity and biochemical responses caused by tris (2-chloroethyl) phosphate and tricresyl phosphate on earthworm - Yang_2018_Ecotoxicol.Environ.Saf_158_78
Author(s) : Yang Y , Xiao Y , Chang Y , Cui Y , Klobucar G , Li M
Ref : Ecotoxicology & Environmental Safety , 158 :78 , 2018
Abstract : Yang_2018_Ecotoxicol.Environ.Saf_158_78
ESTHER : Yang_2018_Ecotoxicol.Environ.Saf_158_78
PubMedSearch : Yang_2018_Ecotoxicol.Environ.Saf_158_78
PubMedID: 29660616

Title : Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice (Mus musculus) - Deng_2018_J.Hazard.Mater_357_348
Author(s) : Deng Y , Zhang Y , Qiao R , Bonilla MM , Yang X , Ren H , Lemos B
Ref : J Hazard Mater , 357 :348 , 2018
Abstract : Deng_2018_J.Hazard.Mater_357_348
ESTHER : Deng_2018_J.Hazard.Mater_357_348
PubMedSearch : Deng_2018_J.Hazard.Mater_357_348
PubMedID: 29908513

Title : Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity - Sun_2016_Neurotoxicol.Teratol_55_16
Author(s) : Sun L , Xu W , Peng T , Chen H , Ren L , Tan H , Xiao D , Qian H , Fu Z
Ref : Neurotoxicology & Teratology , 55 :16 , 2016
Abstract : Sun_2016_Neurotoxicol.Teratol_55_16
ESTHER : Sun_2016_Neurotoxicol.Teratol_55_16
PubMedSearch : Sun_2016_Neurotoxicol.Teratol_55_16
PubMedID: 27018022

Title : Developmental neurotoxicity of organophosphate flame retardants in early life stages of Japanese medaka (Oryzias latipes) - Sun_2016_Environ.Toxicol.Chem_35_2931
Author(s) : Sun L , Tan H , Peng T , Wang S , Xu W , Qian H , Jin Y , Fu Z
Ref : Environ Toxicol Chem , 35 :2931 , 2016
Abstract : Sun_2016_Environ.Toxicol.Chem_35_2931
ESTHER : Sun_2016_Environ.Toxicol.Chem_35_2931
PubMedSearch : Sun_2016_Environ.Toxicol.Chem_35_2931
PubMedID: 27146889

Title : Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and tris(2-chloro-2-ethyl)phosphate (TCEP) - Moser_2015_Neurotoxicol.Teratol_52_236
Author(s) : Moser VC , Phillips PM , Hedge JM , McDaniel KL
Ref : Neurotoxicology & Teratology , 52 :236 , 2015
Abstract : Moser_2015_Neurotoxicol.Teratol_52_236
ESTHER : Moser_2015_Neurotoxicol.Teratol_52_236
PubMedSearch : Moser_2015_Neurotoxicol.Teratol_52_236
PubMedID: 26300399

Title : Monitoring of the three organophosphate esters TBP, TCEP and TBEP in river water and ground water (Oder, Germany) - Fries_2003_J.Environ.Monit_5_346
Author(s) : Fries E , Puttmann W
Ref : J Environ Monit , 5 :346 , 2003
Abstract : Fries_2003_J.Environ.Monit_5_346
ESTHER : Fries_2003_J.Environ.Monit_5_346
PubMedSearch : Fries_2003_J.Environ.Monit_5_346
PubMedID: 12729280

Title : Neurotoxicity of two organophosphorus ester flame retardants in hens - Sprague_1981_J.Toxicol.Environ.Health_8_507
Author(s) : Sprague GL , Sandvik LL , Brookins-Hendricks MJ , Bickford AA
Ref : J Toxicol Environ Health , 8 :507 , 1981
Abstract : Sprague_1981_J.Toxicol.Environ.Health_8_507
ESTHER : Sprague_1981_J.Toxicol.Environ.Health_8_507
PubMedSearch : Sprague_1981_J.Toxicol.Environ.Health_8_507
PubMedID: 7345172