Trichlorfon~Metrifonate
Anthelmintic is used for treating domestic animals for control of internal parasites and has been tested in patients with Alzheimer's disease. Metrifonate is slowly converted in the body by a nonenzymatic process to the long-acting cholinesterase inhibitor Dichlorvos
General
Type : Organophosphate,Insecticide,Anthelmintic
Chemical_Nomenclature : (2,2,2-Trichloro-1-hydroxyethyl)-phosphonic acid dimethyl ester
Canonical SMILES : COP(=O)(C(C(Cl)(Cl)Cl)O)OC
InChI : InChI=1S\/C4H8Cl3O4P\/c1-10-12(9,11-2)3(8)4(5,6)7\/h3,8H,1-2H3
InChIKey : NFACJZMKEDPNKN-UHFFFAOYSA-N
Other name(s) : Trichlorphon,Promem,Metriphonate,Metrifonate,Chlorofos,Dylox,Dipterex,Proxol,Neguvon,MFT
MW : 257.44
Formula : C4H8Cl3O4P
CAS_number : 52-68-6
PubChem : 5853
UniChem : NFACJZMKEDPNKN-UHFFFAOYSA-N
IUPHAR :
Wikipedia : Metrifonate
Target
Families : Trichlorfon~Metrifonate ligand of proteins in family: BCHE || ACHE || ACPH_Peptidase_S9
Stucture :
Protein : human-APEH
References (66)
| Title : Modulation of dopaminergic neurotransmission induced by sublethal Doses of the organophosphate trichlorfon in cockroaches - Daiane_2014_Ecotoxicol.Environ.Saf_109C_56 |
| Author(s) : Daiane Stu Rmer G , de Freitas TC , de Avila Heberle M , de Assis DR , Vinade L , Batista Pereira A , Luis Franco J , Andre Dal Belo C |
| Ref : Ecotoxicology & Environmental Safety , 109C :56 , 2014 |
| Abstract : Daiane_2014_Ecotoxicol.Environ.Saf_109C_56 |
| ESTHER : Daiane_2014_Ecotoxicol.Environ.Saf_109C_56 |
| PubMedSearch : Daiane_2014_Ecotoxicol.Environ.Saf_109C_56 |
| PubMedID: 25164203 |
| Title : Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants - Quistad_2005_Toxicol.Sci_86_291 |
| Author(s) : Quistad GB , Klintenberg R , Casida JE |
| Ref : Toxicol Sci , 86 :291 , 2005 |
| Abstract : Quistad_2005_Toxicol.Sci_86_291 |
| ESTHER : Quistad_2005_Toxicol.Sci_86_291 |
| PubMedSearch : Quistad_2005_Toxicol.Sci_86_291 |
| PubMedID: 15888665 |
| Gene_locus related to this paper: human-APEH |
| Title : Alzheimer's disease: seeking new ways to preserve brain function. Interview by Alice V. Luddington - Davis_1999_Geriatrics_54_42 |
| Author(s) : Davis KL |
| Ref : Geriatrics , 54 :42 , 1999 |
| Abstract : Davis_1999_Geriatrics_54_42 |
| ESTHER : Davis_1999_Geriatrics_54_42 |
| PubMedSearch : Davis_1999_Geriatrics_54_42 |
| PubMedID: 10024872 |
| Title : Metrifonate: overview of safety and efficacy - Cummings_1998_Pharmacotherapy_18_43 |
| Author(s) : Cummings JL |
| Ref : Pharmacotherapy , 18 :43 , 1998 |
| Abstract : Cummings_1998_Pharmacotherapy_18_43 |
| ESTHER : Cummings_1998_Pharmacotherapy_18_43 |
| PubMedSearch : Cummings_1998_Pharmacotherapy_18_43 |
| PubMedID: 9543464 |
| Title : Metrifonate treatment of the cognitive deficits of Alzheimer's disease. Metrifonate Study Group [see comments] [published erratum appears in Neurology 1998 Jul\;51(1):332] - Cummings_1998_Neurology_50_1214 |
| Author(s) : Cummings JL , Cyrus PA , Bieber F , Mas J , Orazem J , Gulanski B |
| Ref : Neurology , 50 :1214 , 1998 |
| Abstract : Cummings_1998_Neurology_50_1214 |
| ESTHER : Cummings_1998_Neurology_50_1214 |
| PubMedSearch : Cummings_1998_Neurology_50_1214 |
| PubMedID: 9595966 |
| Title : Schistosomiasis in Saudi Arabia, Egypt, and Iraq - Youssef_1998_Urology_51_170 |
| Author(s) : Youssef AR , Cannon JM , Al Juburi AZ , Cockett AT |
| Ref : Urology , 51 :170 , 1998 |
| Abstract : Youssef_1998_Urology_51_170 |
| ESTHER : Youssef_1998_Urology_51_170 |
| PubMedSearch : Youssef_1998_Urology_51_170 |
| PubMedID: 9610576 |
| Title : Preclinical pharmacology of metrifonate - Jann_1998_Pharmacotherapy_18_55 |
| Author(s) : Jann MW |
| Ref : Pharmacotherapy , 18 :55 , 1998 |
| Abstract : Jann_1998_Pharmacotherapy_18_55 |
| ESTHER : Jann_1998_Pharmacotherapy_18_55 |
| PubMedSearch : Jann_1998_Pharmacotherapy_18_55 |
| PubMedID: 9543466 |
| Title : Teratogenic effects of trichlorfon (Metrifonate) on the guinea-pig brain. Determination of the effective dose and the sensitive period - Hjelde_1998_Neurochem.Int_32_469 |
| Author(s) : Hjelde T , Mehl A , Schanke TM , Fonnum F |
| Ref : Neurochem Int , 32 :469 , 1998 |
| Abstract : Hjelde_1998_Neurochem.Int_32_469 |
| ESTHER : Hjelde_1998_Neurochem.Int_32_469 |
| PubMedSearch : Hjelde_1998_Neurochem.Int_32_469 |
| PubMedID: 9676746 |
| Title : Pharmacokinetics, pharmacodynamics, and safety of metrifonate in patients with Alzheimer's disease - Pettigrew_1998_J.Clin.Pharmacol_38_236 |
| Author(s) : Pettigrew LC , Bieber F , Lettieri J , Wermeling DP , Schmitt FA , Tikhtman AJ , Ashford JW , Smith CD , Wekstein DR , Markesbery WR , Orazem J , Ruzicka BB , Mas J , Gulanski B |
| Ref : Journal of Clinical Pharmacology , 38 :236 , 1998 |
| Abstract : Pettigrew_1998_J.Clin.Pharmacol_38_236 |
| ESTHER : Pettigrew_1998_J.Clin.Pharmacol_38_236 |
| PubMedSearch : Pettigrew_1998_J.Clin.Pharmacol_38_236 |
| PubMedID: 98210831 |
| Title : Inhibition of carboxylesterases in SH-SY5Y human and NB41A3 mouse neuroblastoma cells by organophosphorus esters - Ehrich_1998_J.Toxicol.Environ.Health_53_385 |
| Author(s) : Ehrich M , Correll L |
| Ref : J Toxicol Environ Health , 53 :385 , 1998 |
| Abstract : Ehrich_1998_J.Toxicol.Environ.Health_53_385 |
| ESTHER : Ehrich_1998_J.Toxicol.Environ.Health_53_385 |
| PubMedSearch : Ehrich_1998_J.Toxicol.Environ.Health_53_385 |
| PubMedID: 9515941 |
| Title : Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: from tacrine to future applications - Giacobini_1998_Neurochem.Int_32_413 |
| Author(s) : Giacobini E |
| Ref : Neurochem Int , 32 :413 , 1998 |
| Abstract : Giacobini_1998_Neurochem.Int_32_413 |
| ESTHER : Giacobini_1998_Neurochem.Int_32_413 |
| PubMedSearch : Giacobini_1998_Neurochem.Int_32_413 |
| PubMedID: 9676739 |
| Title : Safety and tolerability of metrifonate in patients with Alzheimer's disease: results of a maximum tolerated dose study - Cutler_1998_Life.Sci_62_1433 |
| Author(s) : Cutler NR , Jhee SS , Cyrus P , Bieber F , TanPiengco P , Sramek JJ , Gulanski B |
| Ref : Life Sciences , 62 :1433 , 1998 |
| Abstract : Cutler_1998_Life.Sci_62_1433 |
| ESTHER : Cutler_1998_Life.Sci_62_1433 |
| PubMedSearch : Cutler_1998_Life.Sci_62_1433 |
| PubMedID: 9585171 |
| Title : Metrifonate for Alzheimer's disease: is the next cholinesterase inhibitor better? [editorial\; comment] - |
| Author(s) : Knopman DS |
| Ref : Neurology , 50 :1203 , 1998 |
| PubMedID: 9595961 |
| Title : Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease [see comments] - Morris_1998_Neurology_50_1222 |
| Author(s) : Morris JC , Cyrus PA , Orazem J , Mas J , Bieber F , Ruzicka BB , Gulanski B |
| Ref : Neurology , 50 :1222 , 1998 |
| Abstract : Morris_1998_Neurology_50_1222 |
| ESTHER : Morris_1998_Neurology_50_1222 |
| PubMedSearch : Morris_1998_Neurology_50_1222 |
| PubMedID: 9595967 |
| Title : The clinical trial protocol of the Metrifonate in Alzheimer's Trial (MALT) - McKeith_1998_Dement.Geriatr.Cogn.Disord_2_2 |
| Author(s) : McKeith IG |
| Ref : Dementia & Geriatric Cognitive Disorders , 2 :2 , 1998 |
| Abstract : McKeith_1998_Dement.Geriatr.Cogn.Disord_2_2 |
| ESTHER : McKeith_1998_Dement.Geriatr.Cogn.Disord_2_2 |
| PubMedSearch : McKeith_1998_Dement.Geriatr.Cogn.Disord_2_2 |
| PubMedID: 9718228 |
| Title : Beyond the cholinergic hypothesis: the effect of metrifonate and other cholinesterase inhibitors on neuropsychiatric symptoms in Alzheimer's disease - Kaufer_1998_Dement.Geriatr.Cogn.Disord_2_8 |
| Author(s) : Kaufer D |
| Ref : Dementia & Geriatric Cognitive Disorders , 2 :8 , 1998 |
| Abstract : Kaufer_1998_Dement.Geriatr.Cogn.Disord_2_8 |
| ESTHER : Kaufer_1998_Dement.Geriatr.Cogn.Disord_2_8 |
| PubMedSearch : Kaufer_1998_Dement.Geriatr.Cogn.Disord_2_8 |
| PubMedID: 9718229 |
| Title : The pharmacological basis for metrifonate's favourable tolerability in the treatment of Alzheimer's disease - Schmidt_1998_Dement.Geriatr.Cogn.Disord_2_15 |
| Author(s) : Schmidt BH , Heinig R |
| Ref : Dementia & Geriatric Cognitive Disorders , 2 :15 , 1998 |
| Abstract : Schmidt_1998_Dement.Geriatr.Cogn.Disord_2_15 |
| ESTHER : Schmidt_1998_Dement.Geriatr.Cogn.Disord_2_15 |
| PubMedSearch : Schmidt_1998_Dement.Geriatr.Cogn.Disord_2_15 |
| PubMedID: 9718230 |
| Title : Evaluating response to metrifonate - Tariot_1998_J.Clin.Psychiatry_9_33 |
| Author(s) : Tariot PN |
| Ref : J Clin Psychiatry , 9 :33 , 1998 |
| Abstract : Tariot_1998_J.Clin.Psychiatry_9_33 |
| ESTHER : Tariot_1998_J.Clin.Psychiatry_9_33 |
| PubMedSearch : Tariot_1998_J.Clin.Psychiatry_9_33 |
| PubMedID: 9720485 |
| Title : Effect of subchronic treatment with metrifonate and tacrine on brain cholinergic function in aged F344 rats - Giovannini_1998_Eur.J.Pharmacol_354_17 |
| Author(s) : Giovannini MG , Scali C , Bartolini L , Schmidt B , Pepeu G |
| Ref : European Journal of Pharmacology , 354 :17 , 1998 |
| Abstract : Giovannini_1998_Eur.J.Pharmacol_354_17 |
| ESTHER : Giovannini_1998_Eur.J.Pharmacol_354_17 |
| PubMedSearch : Giovannini_1998_Eur.J.Pharmacol_354_17 |
| PubMedID: 9726626 |
| Title : Pharmacokinetics and neurotoxicity of dipterex in hens. A comparative study of administration methods - Xie_1998_J.Toxicol.Sci_23_25 |
| Author(s) : Xie X , Piao FY , Tian Y , Yamauchi T |
| Ref : Journal of Toxicological Sciences , 23 :25 , 1998 |
| Abstract : Xie_1998_J.Toxicol.Sci_23_25 |
| ESTHER : Xie_1998_J.Toxicol.Sci_23_25 |
| PubMedSearch : Xie_1998_J.Toxicol.Sci_23_25 |
| PubMedID: 9513919 |
| Title : Effects of metrifonate on cognitive decline in Alzheimer disease: a double-blind, placebo-controlled, 6-month study - Becker_1998_Alzheimer.Dis.Assoc.Disord_12_54 |
| Author(s) : Becker RE , Colliver JA , Markwell SJ , Moriearty PL , Unni LK , Vicari S |
| Ref : lzheimer Disease & Associated Disorders , 12 :54 , 1998 |
| Abstract : Becker_1998_Alzheimer.Dis.Assoc.Disord_12_54 |
| ESTHER : Becker_1998_Alzheimer.Dis.Assoc.Disord_12_54 |
| PubMedSearch : Becker_1998_Alzheimer.Dis.Assoc.Disord_12_54 |
| PubMedID: 9539412 |
| Title : Effects of metrifonate on radial arm maze acquisition in middle-aged rats - Dachir_1997_Brain.Res_777_251 |
| Author(s) : Dachir S , Schmidt B , Levy A |
| Ref : Brain Research , 777 :251 , 1997 |
| Abstract : Dachir_1997_Brain.Res_777_251 |
| ESTHER : Dachir_1997_Brain.Res_777_251 |
| PubMedSearch : Dachir_1997_Brain.Res_777_251 |
| PubMedID: 9449438 |
| Title : Subchronic treatment increases the duration of the cognitive enhancement induced by metrifonate - Riekkinen_1997_Eur.J.Pharmacol_338_105 |
| Author(s) : Riekkinen M , Schmidt BH , Riekkinen P, Jr. |
| Ref : European Journal of Pharmacology , 338 :105 , 1997 |
| Abstract : Riekkinen_1997_Eur.J.Pharmacol_338_105 |
| ESTHER : Riekkinen_1997_Eur.J.Pharmacol_338_105 |
| PubMedSearch : Riekkinen_1997_Eur.J.Pharmacol_338_105 |
| PubMedID: 9455990 |
| Title : Treating Alzheimer's disease.Pharmacologic options now and in the near future - Tariot_1997_Postgrad.Med_101_73 |
| Author(s) : Tariot PN , Schneider L , Porsteinsson AP |
| Ref : Postgrad Med , 101 :73 , 1997 |
| Abstract : Tariot_1997_Postgrad.Med_101_73 |
| ESTHER : Tariot_1997_Postgrad.Med_101_73 |
| PubMedSearch : Tariot_1997_Postgrad.Med_101_73 |
| PubMedID: 9194867 |
| Title : [The pharmacokinetic interaction of cholinolytics and cholinesterase reactivators as a reflection of the modulation of their binding in blood plasma and in brain tissue] - Elaeva_1997_Eksp.Klin.Farmakol_60_64 |
| Author(s) : Elaeva NL , Predtechenskii MB , Kul'bitskii GN , Babaina EV , Trefilov VV |
| Ref : Eksperimentalnaia i Klinicheskaia Farmakologiia , 60 :64 , 1997 |
| Abstract : Elaeva_1997_Eksp.Klin.Farmakol_60_64 |
| ESTHER : Elaeva_1997_Eksp.Klin.Farmakol_60_64 |
| PubMedSearch : Elaeva_1997_Eksp.Klin.Farmakol_60_64 |
| PubMedID: 9376763 |
| Title : Subchronic neurotoxicity screening studies with six organophosphate insecticides: an assessment of behavior and morphology relative to cholinesterase inhibition - Sheets_1997_Fundam.Appl.Toxicol_35_101 |
| Author(s) : Sheets LP , Hamilton BF , Sangha GK , Thyssen JH |
| Ref : Fundamental & Applied Toxicology , 35 :101 , 1997 |
| Abstract : Sheets_1997_Fundam.Appl.Toxicol_35_101 |
| ESTHER : Sheets_1997_Fundam.Appl.Toxicol_35_101 |
| PubMedSearch : Sheets_1997_Fundam.Appl.Toxicol_35_101 |
| PubMedID: 9024678 |
| Title : Effects of combined chronic nimodipine and acute metrifonate treatment on spatial and avoidance behavior - Riekkinen_1997_Eur.J.Pharmacol_322_1 |
| Author(s) : Riekkinen M , Schmidt B , Kuitunen J , Riekkinen P |
| Ref : European Journal of Pharmacology , 322 :1 , 1997 |
| Abstract : Riekkinen_1997_Eur.J.Pharmacol_322_1 |
| ESTHER : Riekkinen_1997_Eur.J.Pharmacol_322_1 |
| PubMedSearch : Riekkinen_1997_Eur.J.Pharmacol_322_1 |
| PubMedID: 9088863 |
| Title : Effects of metrifonate on memory impairment and cholinergic dysfunction in rats - Itoh_1997_Eur.J.Pharmacol_322_11 |
| Author(s) : Itoh A , Nitta A , Katono Y , Usui M , Naruhashi K , Iida R , Hasegawa T , Nabeshima T |
| Ref : European Journal of Pharmacology , 322 :11 , 1997 |
| Abstract : Itoh_1997_Eur.J.Pharmacol_322_11 |
| ESTHER : Itoh_1997_Eur.J.Pharmacol_322_11 |
| PubMedSearch : Itoh_1997_Eur.J.Pharmacol_322_11 |
| PubMedID: 9088864 |
| Title : Behavioral characterization of metrifonate-improved acquisition of spatial information in medial septum-lesioned rats - Riekkinen_1997_Eur.J.Pharmacol_323_11 |
| Author(s) : Riekkinen P, Jr. , Schmidt B , Riekkinen M |
| Ref : European Journal of Pharmacology , 323 :11 , 1997 |
| Abstract : Riekkinen_1997_Eur.J.Pharmacol_323_11 |
| ESTHER : Riekkinen_1997_Eur.J.Pharmacol_323_11 |
| PubMedSearch : Riekkinen_1997_Eur.J.Pharmacol_323_11 |
| PubMedID: 9105871 |
| Title : Effect of metrifonate on extracellular brain acetylcholine and object recognition in aged rats - Scali_1997_Eur.J.Pharmacol_325_173 |
| Author(s) : Scali C , Giovannini MG , Bartolini L , Prosperi C , Hinz V , Schmidt B , Pepeu G |
| Ref : European Journal of Pharmacology , 325 :173 , 1997 |
| Abstract : Scali_1997_Eur.J.Pharmacol_325_173 |
| ESTHER : Scali_1997_Eur.J.Pharmacol_325_173 |
| PubMedSearch : Scali_1997_Eur.J.Pharmacol_325_173 |
| PubMedID: 9163564 |
| Title : Metrifonate treatment enhances acquisition of eyeblink conditioning in aging rabbits - Kronforst-Collins_1997_Pharmacol.Biochem.Behav_56_103 |
| Author(s) : Kronforst-Collins MA , Moriearty PL , Ralph M , Becker RE , Schmidt B , Thompson LT , Disterhoft JF |
| Ref : Pharmacology, Biochemistry & Behavior , 56 :103 , 1997 |
| Abstract : Kronforst-Collins_1997_Pharmacol.Biochem.Behav_56_103 |
| ESTHER : Kronforst-Collins_1997_Pharmacol.Biochem.Behav_56_103 |
| PubMedSearch : Kronforst-Collins_1997_Pharmacol.Biochem.Behav_56_103 |
| PubMedID: 8981616 |
| Title : Metrifonate improves associative learning and retention in aging rabbits - Kronforst-Collins_1997_Behav.Neurosci_111_1031 |
| Author(s) : Kronforst-Collins MA , Moriearty PL , Schmidt B , Disterhoft JF |
| Ref : Behavioral Neuroscience , 111 :1031 , 1997 |
| Abstract : Kronforst-Collins_1997_Behav.Neurosci_111_1031 |
| ESTHER : Kronforst-Collins_1997_Behav.Neurosci_111_1031 |
| PubMedSearch : Kronforst-Collins_1997_Behav.Neurosci_111_1031 |
| PubMedID: 9383522 |
| Title : Effects of cholinesterase inhibitors on the secretion of beta-amyloid precursor protein in cell cultures - Lahiri_1997_Ann.N.Y.Acad.Sci_826_416 |
| Author(s) : Lahiri DK , Farlow MR , Nurnberger JI, Jr. , Greig NH |
| Ref : Annals of the New York Academy of Sciences , 826 :416 , 1997 |
| Abstract : Lahiri_1997_Ann.N.Y.Acad.Sci_826_416 |
| ESTHER : Lahiri_1997_Ann.N.Y.Acad.Sci_826_416 |
| PubMedSearch : Lahiri_1997_Ann.N.Y.Acad.Sci_826_416 |
| PubMedID: 9329715 |
| Title : Human mortality in organophosphate poisonings - Yamashita_1997_Vet.Hum.Toxicol_39_84 |
| Author(s) : Yamashita M , Tanaka J , Ando Y |
| Ref : Vet Hum Toxicol , 39 :84 , 1997 |
| Abstract : Yamashita_1997_Vet.Hum.Toxicol_39_84 |
| ESTHER : Yamashita_1997_Vet.Hum.Toxicol_39_84 |
| PubMedSearch : Yamashita_1997_Vet.Hum.Toxicol_39_84 |
| PubMedID: 9080632 |
| Title : Chronic nimodipine and acute metrifonate treatment decreases age- related cortical high voltage spindles in rats - Riekkinen_1997_Psychopharmacology_129_91 |
| Author(s) : Riekkinen P, Jr. , Schmidt B , Jakala P , Koivisto E , Bjorklund M |
| Ref : Psychopharmacology , 129 :91 , 1997 |
| Abstract : Riekkinen_1997_Psychopharmacology_129_91 |
| ESTHER : Riekkinen_1997_Psychopharmacology_129_91 |
| PubMedSearch : Riekkinen_1997_Psychopharmacology_129_91 |
| PubMedID: 9122369 |
| Title : Effects of metrifonate on impairment of learning and dysfunction of cholinergic neuronal system in basal forebrain-lesioned rats - Itoh_1997_Behav.Brain.Res_83_165 |
| Author(s) : Itoh A , Nitta A , Hirose M , Hasegawa T , Nabeshima T |
| Ref : Behavioural Brain Research , 83 :165 , 1997 |
| Abstract : Itoh_1997_Behav.Brain.Res_83_165 |
| ESTHER : Itoh_1997_Behav.Brain.Res_83_165 |
| PubMedSearch : Itoh_1997_Behav.Brain.Res_83_165 |
| PubMedID: 9062677 |
| Title : Using the Hungarian Birth Defects Registry for surveillance, research and intervention - Siffel_1997_Cent.Eur.J.Public.Health_5_79 |
| Author(s) : Siffel C , Czeizel AE |
| Ref : Central European Journal of Public Health , 5 :79 , 1997 |
| Abstract : Siffel_1997_Cent.Eur.J.Public.Health_5_79 |
| ESTHER : Siffel_1997_Cent.Eur.J.Public.Health_5_79 |
| PubMedSearch : Siffel_1997_Cent.Eur.J.Public.Health_5_79 |
| PubMedID: 9208163 |
| Title : [Recent data on the treatment of bovine hypodermyiasis using metrifonate (Neguvon) and ivermectin (Ivomec) in microdoses] - Charbon_1997_Schweiz.Arch.Tierheilkd_139_550 |
| Author(s) : Charbon JL , Pfister K |
| Ref : Schweiz Arch Tierheilkd , 139 :550 , 1997 |
| Abstract : Charbon_1997_Schweiz.Arch.Tierheilkd_139_550 |
| ESTHER : Charbon_1997_Schweiz.Arch.Tierheilkd_139_550 |
| PubMedSearch : Charbon_1997_Schweiz.Arch.Tierheilkd_139_550 |
| PubMedID: 9451918 |
| Title : Effects of metrifonate, a cholinesterase inhibitor, on local cerebral glucose utilization in young and aged rats - Bassant_1996_J.Cereb.Blood.Flow.Metab_16_1014 |
| Author(s) : Bassant MH , Jazat-Poindessous F , Lamour Y |
| Ref : Journal of Cerebral Blood Flow & Metabolism , 16 :1014 , 1996 |
| Abstract : Bassant_1996_J.Cereb.Blood.Flow.Metab_16_1014 |
| ESTHER : Bassant_1996_J.Cereb.Blood.Flow.Metab_16_1014 |
| PubMedSearch : Bassant_1996_J.Cereb.Blood.Flow.Metab_16_1014 |
| PubMedID: 8784247 |
| Title : An indirect cholinesterase inhibitor, metrifonate, increases neocortical EEG arousal in rats - Bjorklund_1996_Neuroreport_7_1097 |
| Author(s) : Bjorklund M , Jakala P , Schmidt B , Riekkinen M , Koivisto E , Riekkinen P, Jr. |
| Ref : Neuroreport , 7 :1097 , 1996 |
| Abstract : Bjorklund_1996_Neuroreport_7_1097 |
| ESTHER : Bjorklund_1996_Neuroreport_7_1097 |
| PubMedSearch : Bjorklund_1996_Neuroreport_7_1097 |
| PubMedID: 8804059 |
| Title : Metrifonate improves spatial navigation and avoidance behavior in scopolamine-treated, medial septum-lesioned and aged rats - Riekkinen_1996_Eur.J.Pharmacol_309_121 |
| Author(s) : Riekkinen P, Jr. , Schmidt B , Stefanski R , Kuitunen J , Riekkinen M |
| Ref : European Journal of Pharmacology , 309 :121 , 1996 |
| Abstract : Riekkinen_1996_Eur.J.Pharmacol_309_121 |
| ESTHER : Riekkinen_1996_Eur.J.Pharmacol_309_121 |
| PubMedSearch : Riekkinen_1996_Eur.J.Pharmacol_309_121 |
| PubMedID: 8874130 |
| Title : A study of the aneugenic activity of trichlorfon detected by centromere- specific probes in human lymphoblastoid cell lines - Doherty_1996_Mutat.Res_372_221 |
| Author(s) : Doherty AT , Ellard S , Parry EM , Parry JM |
| Ref : Mutat Res , 372 :221 , 1996 |
| Abstract : Doherty_1996_Mutat.Res_372_221 |
| ESTHER : Doherty_1996_Mutat.Res_372_221 |
| PubMedSearch : Doherty_1996_Mutat.Res_372_221 |
| PubMedID: 9015141 |
| Title : Effects of combined nimodipine and metrifonate on rat cognition and cortical EEG - Jakala_1996_Eur.J.Pharmacol_318_239 |
| Author(s) : Jakala P , Riekkinen M , Bjorklund M , Koivisto E , Schmidt B , Riekkinen P, Jr. |
| Ref : European Journal of Pharmacology , 318 :239 , 1996 |
| Abstract : Jakala_1996_Eur.J.Pharmacol_318_239 |
| ESTHER : Jakala_1996_Eur.J.Pharmacol_318_239 |
| PubMedSearch : Jakala_1996_Eur.J.Pharmacol_318_239 |
| PubMedID: 9016911 |
| Title : [Twenty-years health surveillance of workers in dipterex packaging] - Sun_1996_Chung.Hua.Yu.Fang.I.Hsueh.Tsa.Chih_30_273 |
| Author(s) : Sun D , Zhou H , Huang J |
| Ref : Chinese Journal of Preventive Medicine , 30 :273 , 1996 |
| Abstract : Sun_1996_Chung.Hua.Yu.Fang.I.Hsueh.Tsa.Chih_30_273 |
| ESTHER : Sun_1996_Chung.Hua.Yu.Fang.I.Hsueh.Tsa.Chih_30_273 |
| PubMedSearch : Sun_1996_Chung.Hua.Yu.Fang.I.Hsueh.Tsa.Chih_30_273 |
| PubMedID: 9388884 |
| Title : Schistosoma: rate of glucose import is altered by acetylcholine interaction with tegumental acetylcholine receptors and acetylcholinesterase - Camacho_1995_Exp.Parasitol_81_584 |
| Author(s) : Camacho M , Agnew A |
| Ref : Experimental Parasitology , 81 :584 , 1995 |
| Abstract : Camacho_1995_Exp.Parasitol_81_584 |
| ESTHER : Camacho_1995_Exp.Parasitol_81_584 |
| PubMedSearch : Camacho_1995_Exp.Parasitol_81_584 |
| PubMedID: 8543000 |
| Title : Cholinesterase inhibitors proposed for treating dementia in Alzheimer's disease: selectivity toward human brain acetylcholinesterase compared with butyrylcholinesterase - Pacheco_1995_J.Pharmacol.Exp.Ther_274_767 |
| Author(s) : Pacheco G , Palacios-Esquivel R , Moss DE |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 274 :767 , 1995 |
| Abstract : Pacheco_1995_J.Pharmacol.Exp.Ther_274_767 |
| ESTHER : Pacheco_1995_J.Pharmacol.Exp.Ther_274_767 |
| PubMedSearch : Pacheco_1995_J.Pharmacol.Exp.Ther_274_767 |
| PubMedID: 7636741 |
| Title : The amount of acetylcholinesterase on the parasite surface reflects the differential sensitivity of schistosome species to metrifonate - Camacho_1994_Parasitology_108_153 |
| Author(s) : Camacho M , Tarrab-Hazdai R , Espinoza B , Arnon R , Agnew A |
| Ref : Parasitology , 108 :153 , 1994 |
| Abstract : Camacho_1994_Parasitology_108_153 |
| ESTHER : Camacho_1994_Parasitology_108_153 |
| PubMedSearch : Camacho_1994_Parasitology_108_153 |
| PubMedID: 8159460 |
| Title : Transdermal patch delivery of acetylcholinesterase inhibitors - Moriearty_1993_Meth.Find.Exp.Clin.Pharmacol_15_407 |
| Author(s) : Moriearty PL , Thornton SL , Becker RE |
| Ref : Methods Find Exp Clin Pharmacol , 15 :407 , 1993 |
| Abstract : Moriearty_1993_Meth.Find.Exp.Clin.Pharmacol_15_407 |
| ESTHER : Moriearty_1993_Meth.Find.Exp.Clin.Pharmacol_15_407 |
| PubMedSearch : Moriearty_1993_Meth.Find.Exp.Clin.Pharmacol_15_407 |
| PubMedID: 8231460 |
| Title : [A study on acute organophosphorus poisoning--changes in the activity and isoenzyme patterns of serum cholinesterase in human poisoning]. [Japanese] - Yamanaka_1993_Japanese.J.Hyg_48_955 |
| Author(s) : Yamanaka S , Yoshida M , Yamamura Y , Nishimura M , Takaesu Y |
| Ref : Nippon Eiseigaku Zasshi Japanese Journal of Hygiene , 48 :955 , 1993 |
| Abstract : Yamanaka_1993_Japanese.J.Hyg_48_955 |
| ESTHER : Yamanaka_1993_Japanese.J.Hyg_48_955 |
| PubMedSearch : Yamanaka_1993_Japanese.J.Hyg_48_955 |
| PubMedID: 8107298 |
| Title : Preferential inhibition of acetylcholinesterase molecular forms in rat brain - Ogane_1992_Neurochem.Res_17_489 |
| Author(s) : Ogane N , Giacobini E , Messamore E |
| Ref : Neurochemical Research , 17 :489 , 1992 |
| Abstract : Ogane_1992_Neurochem.Res_17_489 |
| ESTHER : Ogane_1992_Neurochem.Res_17_489 |
| PubMedSearch : Ogane_1992_Neurochem.Res_17_489 |
| PubMedID: 1528356 |
| Title : Treatment and control of sarcoptic mange: evaluation of treatment of both the pigs and environment - Kambarage_1991_Trop.Anim.Health.Prod_23_59 |
| Author(s) : Kambarage DM |
| Ref : Trop Anim Health Prod , 23 :59 , 1991 |
| Abstract : Kambarage_1991_Trop.Anim.Health.Prod_23_59 |
| ESTHER : Kambarage_1991_Trop.Anim.Health.Prod_23_59 |
| PubMedSearch : Kambarage_1991_Trop.Anim.Health.Prod_23_59 |
| PubMedID: 1903897 |
| Title : [Insecticide resistance in the Musca domestica populations of the GDR 1976-1988] - Muller_1989_Angew.Parasitol_30_145 |
| Author(s) : Muller P |
| Ref : Angew Parasitol , 30 :145 , 1989 |
| Abstract : Muller_1989_Angew.Parasitol_30_145 |
| ESTHER : Muller_1989_Angew.Parasitol_30_145 |
| PubMedSearch : Muller_1989_Angew.Parasitol_30_145 |
| PubMedID: 2782668 |
| Title : The effect of the organophosphate trichlorfon on the neuromuscular blocking activity of atracurium in halothane-anesthetized horses - Hildebrand_1989_J.Vet.Pharmacol.Ther_12_277 |
| Author(s) : Hildebrand SV , Hill Td , Holland M |
| Ref : J Vet Pharmacol Ther , 12 :277 , 1989 |
| Abstract : Hildebrand_1989_J.Vet.Pharmacol.Ther_12_277 |
| ESTHER : Hildebrand_1989_J.Vet.Pharmacol.Ther_12_277 |
| PubMedSearch : Hildebrand_1989_J.Vet.Pharmacol.Ther_12_277 |
| PubMedID: 2810476 |
| Title : [Effect of the organophosphorus compound neguvon on the dopamine content in the rat brain]. [Bulgarian] - Dishovski_1981_Eksp.Med.Morfol_20_62 |
| Author(s) : Dishovski K , Panova I , Uzunov P |
| Ref : Eksperimentalna Meditsina i Morfologiia , 20 :62 , 1981 |
| Abstract : Dishovski_1981_Eksp.Med.Morfol_20_62 |
| ESTHER : Dishovski_1981_Eksp.Med.Morfol_20_62 |
| PubMedSearch : Dishovski_1981_Eksp.Med.Morfol_20_62 |
| PubMedID: 7250022 |
| Title : [Changes in the transverse striated musculature during treatment with the pesticide, Neguvon, and TMB-4(Trimedoxime) reactivator]. [Bulgarian] - Dzhirkolova_1979_Eksp.Med.Morfol_18_31 |
| Author(s) : Dzhirkolova T , Dishovski K , Rusev G |
| Ref : Eksperimentalna Meditsina i Morfologiia , 18 :31 , 1979 |
| Abstract : Dzhirkolova_1979_Eksp.Med.Morfol_18_31 |
| ESTHER : Dzhirkolova_1979_Eksp.Med.Morfol_18_31 |
| PubMedSearch : Dzhirkolova_1979_Eksp.Med.Morfol_18_31 |
| PubMedID: 436709 |
| Title : [Mutagenic effect of several pesticides on durum spring wheat] - Logvinenko_1978_Tsitol.Genet_12_207 |
| Author(s) : Logvinenko VF , Morgun VV |
| Ref : Tsitol Genet , 12 :207 , 1978 |
| Abstract : Logvinenko_1978_Tsitol.Genet_12_207 |
| ESTHER : Logvinenko_1978_Tsitol.Genet_12_207 |
| PubMedSearch : Logvinenko_1978_Tsitol.Genet_12_207 |
| PubMedID: 684827 |
| Title : [Cytogenetic activity of the pesticides phthalophos, chlorophos and gardona in a culture of human lymphocytes] - Kurinnyi_1977_Genetika_13_337 |
| Author(s) : Kurinnyi AI , Pilinskaia MA |
| Ref : Genetika , 13 :337 , 1977 |
| Abstract : Kurinnyi_1977_Genetika_13_337 |
| ESTHER : Kurinnyi_1977_Genetika_13_337 |
| PubMedSearch : Kurinnyi_1977_Genetika_13_337 |
| PubMedID: 892431 |
| Title : [The effect of dimethoate selection on trichlorfon and dimethoate sensitivity in Musca domestica] - Muller_1977_Angew.Parasitol_18_94 |
| Author(s) : Muller P |
| Ref : Angew Parasitol , 18 :94 , 1977 |
| Abstract : Muller_1977_Angew.Parasitol_18_94 |
| ESTHER : Muller_1977_Angew.Parasitol_18_94 |
| PubMedSearch : Muller_1977_Angew.Parasitol_18_94 |
| PubMedID: 931124 |
| Title : [Effect of insecticides on larvae of Musca domestica in swine manure], - Schneider_1976_Angew.Parasitol_17_128 |
| Author(s) : Schneider M , Groth U |
| Ref : Angew Parasitol , 17 :128 , 1976 |
| Abstract : Schneider_1976_Angew.Parasitol_17_128 |
| ESTHER : Schneider_1976_Angew.Parasitol_17_128 |
| PubMedSearch : Schneider_1976_Angew.Parasitol_17_128 |
| PubMedID: 824979 |
| Title : Experimental study of the effect of a series of phosphoroorganic pesticides (Dipterex and Imidan) on embryogenesis - Martson_1976_Environ.Health.Perspect_13_121 |
| Author(s) : Martson LV , Voronina VM |
| Ref : Environmental Health Perspectives , 13 :121 , 1976 |
| Abstract : Martson_1976_Environ.Health.Perspect_13_121 |
| ESTHER : Martson_1976_Environ.Health.Perspect_13_121 |
| PubMedSearch : Martson_1976_Environ.Health.Perspect_13_121 |
| PubMedID: 1269499 |
| Title : Developmental toxicity in the rat after ingestion or gavage of organophosphate pesticides (Dipterex, Imidan) during pregnancy - Staples_1976_Environ.Health.Perspect_13_133 |
| Author(s) : Staples RE , Kellam RG , Haseman JK |
| Ref : Environmental Health Perspectives , 13 :133 , 1976 |
| Abstract : Staples_1976_Environ.Health.Perspect_13_133 |
| ESTHER : Staples_1976_Environ.Health.Perspect_13_133 |
| PubMedSearch : Staples_1976_Environ.Health.Perspect_13_133 |
| PubMedID: 944629 |
| Title : Studies on Parafilaria bovicola (Tubangui 1934). 1. Clinical observations and chemotherapy - Viljoen_1976_J.S.Afr.Vet.Assoc_47_161 |
| Author(s) : Viljoen JH |
| Ref : J S Afr Vet Assoc , 47 :161 , 1976 |
| Abstract : Viljoen_1976_J.S.Afr.Vet.Assoc_47_161 |
| ESTHER : Viljoen_1976_J.S.Afr.Vet.Assoc_47_161 |
| PubMedSearch : Viljoen_1976_J.S.Afr.Vet.Assoc_47_161 |
| PubMedID: 994132 |
| Title : The activities of some esterases of the rat brain after intoxication by organophosphate insecticides, dichlorvos and trichlorphon - |
| Author(s) : Pachecka J , Sulinski A , Ziolkowska G |
| Ref : Neuropatol Pol , 13 :455 , 1975 |
| PubMedID: 1207914 |
| Title : Problems of housefly (Musca domestica) control due to multiresistance to insesticides - Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340 |
| Author(s) : Keiding J |
| Ref : J Hyg Epidemiol Microbiol Immunol , 19 :340 , 1975 |
| Abstract : Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340 |
| ESTHER : Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340 |
| PubMedSearch : Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340 |
| PubMedID: 52667 |
| Title : [Use of oxygen under pressure in the treatment of acute chlorophos poisoning]. [Russian] - |
| Author(s) : Savateev NV , Brestkina LM , Tonkopii VD , Pozharissakaia TD , Frolov SF |
| Ref : Farmakologiia i Toksikologiia , 35 :738 , 1972 |
| PubMedID: 4651812 |