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Inhibitor Report for: Terbam

Lead compound for search of new insecticides with improved efficacy and specificity for AChEs of arthropod pests.


General
Type Carbamate, Insecticide, tert-Butyl
Chemical_Nomenclature (3-tert-butylphenyl) N-methylcarbamate
Canonical SMILES CC(C)(C)C1=CC(=CC=C1)OC(=O)NC
InChI InChI=1S/C12H17NO2/c1-12(2,3)9-6-5-7-10(8-9)15-11(14)13-4/h5-8H,1-4H3,(H,13,14)
InChIKey FSJYRLHKLVGCNH-UHFFFAOYSA-N
Other name(s) Knockbal ; TBPMC ; Phenol, 3-(1,1-dimethylethyl)-, methylcarbamate ; SCHEMBL78061 ; ZINC2031110 ; CHEMBL2046821
________________________________________________________________________________________________
MW|207.27
Formula|C12H17NO2
CAS_number|780-11-0
PubChem|13072
UniChem|FSJYRLHKLVGCNH-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | Terbam ligand of proteins in family: ACHE

References:
Search PubMed for references concerning: Terbam
    Title: Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates
    Mutunga JM, Ma M, Chen QH, Hartsel JA, Wong DM, Ding S, Totrov M, Carlier PR, Bloomquist JR
    Ref: Int J Environ Research Public Health, 16:, 2019 : PubMed

            

    Title: Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): construction, expression and biochemical properties of the G119S orthologous mutant
    Temeyer KB, Tong F, Totrov MM, Tuckow AP, Chen QH, Carlier PR, Perez de Leon AA, Bloomquist JR
    Ref: Parasit Vectors, 7:577, 2014 : PubMed