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Inhibitor Report for: SCHEMBL19421119

General
Type Azaspiro, Azetidin
Chemical_Nomenclature 2-[3-[(3-chloro-4-methylphenyl)methoxy]azetidine-1-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
Canonical SMILES CC1=C(C=C(C=C1)COC2CN(C2)C(=O)C3CC4(C3)COC(=O)N4)Cl
InChI InChI=1S/C18H21ClN2O4/c1-11-2-3-12(4-15(11)19)9-24-14-7-21(8-14)16(22)13-5-18(6-13)10-25-17(23)20-18/h2-4,13-14H,5-10H2,1H3,(H,20,23)
InChIKey AKBHYCHPWZPGAH-UHFFFAOYSA-N
Other name(s) SCHEMBL19409503 ; SCHEMBL19409505
________________________________________________________________________________________________
MW|364.8
Formula|C18H21ClN2O4
CAS_number|
PubChem|130475870
UniChem|AKBHYCHPWZPGAH-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | SCHEMBL19421119 ligand of proteins in family: Monoglyceridelipase_lysophospholip
Stucture | 1 structure: 7L50: Crystal structure of human monoacylglycerol lipase in complex with compound SCHEMBL19421119
Protein | human-MGLL

References:
Search PubMed for references concerning: SCHEMBL19421119
    Title: Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety
    Ikeda S, Sugiyama H, Tokuhara H, Murakami M, Nakamura M, Oguro Y, Aida J, Morishita N, Sogabe S and Kamata M <9 more author(s)>
    Ref: Journal of Medicinal Chemistry, :, 2021 : PubMed