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Inhibitor Report for: QADD2

competitive antagonist for strigolactone receptors


General
Type Quinazoline
Chemical_Nomenclature 1-(4-hydroxy-3-nitrophenyl)quinazoline-2,4(1H,3H)-dione
Canonical SMILES C1=CC=CC2=C1C(NC(N2C3=CC=C(C(=C3)[N+](=O)[O-])O)=O)=O
InChI InChI=1S/C14H9N3O5/c18-12-6-5-8(7-11(12)17(21)22)16-10-4-2-1-3-9(10)13(19)15-14(16)20/h1-7,18H,(H,15,19,20)
InChIKey YVQCKIRAVMSRGN-UHFFFAOYSA-N
Other name(s) 1-(3-Nitro-4-hydroxyphenyl)-1H-quinazoline-2,4-dione ; LM7
________________________________________________________________________________________________
MW|299.24
Formula|C14H9N3O5
CAS_number|
PubChem|138454260
UniChem|YVQCKIRAVMSRGN-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | QADD2 ligand of proteins in family: RsbQ-like
Stucture | 1 structure: 6O5J: Crystal Structure of DAD2 bound to quinazolinone derivative
Protein | pethy-dad2

References:
Search PubMed for references concerning: QADD2
    Title: Chemical synthesis and characterization of a new quinazolinedione competitive antagonist for strigolactone receptors with an unexpected binding mode
    Hamiaux C, Larsen L, Lee HW, Luo Z, Sharma P, Hawkins BC, Perry NB, Snowden KC
    Ref: Biochemical Journal, 476:1843, 2019 : PubMed