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Pyraclofos

General

Type : Organophosphate,Insecticide,Sulfur Compound,Pyrazole

Chemical_Nomenclature : 1-(4-chlorophenyl)-4-[ethoxy(propylsulfanyl)phosphoryl]oxypyrazole

Canonical SMILES : CCCSP(=O)(OCC)OC1=CN(N=C1)C2=CC=C(C=C2)Cl

InChI : InChI=1S\/C14H18ClN2O3PS\/c1-3-9-22-21(18,19-4-2)20-14-10-16-17(11-14)13-7-5-12(15)6-8-13\/h5-8,10-11H,3-4,9H2,1-2H3

InChIKey : QHGVXILFMXYDRS-UHFFFAOYSA-N

Other name(s) : Boltage,Voltage,TIA 230,OMS 3040,(RS)-O-1-(4-Chlorophenyl)pyrazol-4-yl O-ethyl S-propyl phosphorothioate,O-(1-(4-Chlorophenyl)-1H-pyrazol-4-yl) O-ethyl S-propyl phosphorothioate,(+-)-O-(1-(4-Chlorophenyl)-1H-pyrazol-4-yl) O-ethyl S-propyl phosphorothioate,(RS)-(O-1-(4-Chlorophenyl)pyrazol-4-yl-O-ethyl-S-propylphosphorothioate) (IUPAC),Phosphorothioic acid, O-(1-(4-chlorophenyl)-1H-pyrazol-4-yl) O-ethyl S-propyl ester

MW : 360.8

Formula : C14H18ClN2O3PS

CAS_number : 77458-01-6

PubChem : 93460

UniChem : QHGVXILFMXYDRS-UHFFFAOYSA-N

Target

Families : Pyraclofos ligand of proteins in family
ACHE

References (6)

Title : Characterizing the potentially neuronal acetylcholinesterase reactivity toward chiral pyraclofos: Enantioselective insights from spectroscopy, in silico docking, molecular dynamics simulation and per-residue energy decomposition studies - Peng_2021_J.Mol.Graph.Model_110_108069
Author(s) : Peng W , Wang T , Liang XR , Yang YS , Wang QZ , Cheng HF , Peng YK , Ding F
Ref : J Mol Graph Model , 110 :108069 , 2021
Abstract : Peng_2021_J.Mol.Graph.Model_110_108069
ESTHER : Peng_2021_J.Mol.Graph.Model_110_108069
PubMedSearch : Peng_2021_J.Mol.Graph.Model_110_108069
PubMedID: 34773872

Title : [Multiresidue analysis of organophosphorus pesticides in vegetables and fruits using dual-column GC-FPD, -NPD] - Ueno_2001_Shokuhin.Eiseigaku.Zasshi_42_385
Author(s) : Ueno E , Oshima H , Saito I , Matsumoto H
Ref : Shokuhin Eiseigaku Zasshi , 42 :385 , 2001
Abstract : Ueno_2001_Shokuhin.Eiseigaku.Zasshi_42_385
ESTHER : Ueno_2001_Shokuhin.Eiseigaku.Zasshi_42_385
PubMedSearch : Ueno_2001_Shokuhin.Eiseigaku.Zasshi_42_385
PubMedID: 11875824

Title : Risk assessment of etofenprox (Vectron) on non-target aquatic fauna compared with other pesticides used as Simulium larvicide in a tropical environment - Yameogo_2001_Chemosphere_42_965
Author(s) : Yameogo L , Traore K , Back C , Hougard JM , Calamari D
Ref : Chemosphere , 42 :965 , 2001
Abstract : Yameogo_2001_Chemosphere_42_965
ESTHER : Yameogo_2001_Chemosphere_42_965
PubMedSearch : Yameogo_2001_Chemosphere_42_965
PubMedID: 11272920

Title : Hut-scale trial of pyraclofos against malaria vectors in Malkangiri District of Orissa - Sahu_1996_Indian.J.Malariol_33_16
Author(s) : Sahu SS
Ref : Indian J Malariol , 33 :16 , 1996
Abstract : Sahu_1996_Indian.J.Malariol_33_16
ESTHER : Sahu_1996_Indian.J.Malariol_33_16
PubMedSearch : Sahu_1996_Indian.J.Malariol_33_16
PubMedID: 8690128

Title : Laboratory toxicity of potential blackfly larvicides on some African fish species in the Onchocerciasis Control Programme area - Yameogo_1991_Ecotoxicol.Environ.Saf_21_248
Author(s) : Yameogo L , Tapsoba JM , Calamari D
Ref : Ecotoxicology & Environmental Safety , 21 :248 , 1991
Abstract : Yameogo_1991_Ecotoxicol.Environ.Saf_21_248
ESTHER : Yameogo_1991_Ecotoxicol.Environ.Saf_21_248
PubMedSearch : Yameogo_1991_Ecotoxicol.Environ.Saf_21_248
PubMedID: 1868781

Title : Insecticidal activity of carbosulfan (OMS 3022) and pyraclofos (OMS 3040) against mosquitoes - Velayudhan_1990_J.Commun.Dis_22_140
Author(s) : Velayudhan R , Amalraj D , Arunachalam N , Das PK
Ref : J Commun Dis , 22 :140 , 1990
Abstract : Velayudhan_1990_J.Commun.Dis_22_140
ESTHER : Velayudhan_1990_J.Commun.Dis_22_140
PubMedSearch : Velayudhan_1990_J.Commun.Dis_22_140
PubMedID: 1983012 
Array
(
    [id] => 4587
    [inhibitor] => Pyraclofos
    [type] => Array
        (
            [0] => Organophosphate
            [1] => Insecticide
            [2] => Sulfur Compound
            [3] => Pyrazole
        )

    [other_name] => Array
        (
            [0] => Boltage
            [1] => Voltage
            [2] => TIA 230
            [3] => OMS 3040
            [4] => (RS)-O-1-(4-Chlorophenyl)pyrazol-4-yl O-ethyl S-propyl phosphorothioate
            [5] => O-(1-(4-Chlorophenyl)-1H-pyrazol-4-yl) O-ethyl S-propyl phosphorothioate
            [6] => (+-)-O-(1-(4-Chlorophenyl)-1H-pyrazol-4-yl) O-ethyl S-propyl phosphorothioate
            [7] => (RS)-(O-1-(4-Chlorophenyl)pyrazol-4-yl-O-ethyl-S-propylphosphorothioate) (IUPAC)
            [8] => Phosphorothioic acid, O-(1-(4-chlorophenyl)-1H-pyrazol-4-yl) O-ethyl S-propyl ester
        )

    [chemical_nomenclature] => 1-(4-chlorophenyl)-4-[ethoxy(propylsulfanyl)phosphoryl]oxypyrazole
    [formula] => C14H18ClN2O3PS
    [cas_number] => 77458-01-6
    [mw] => 360.8
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Peng_2021_J.Mol.Graph.Model_110_108069 || Ueno_2001_Shokuhin.Eiseigaku.Zasshi_42_385 || Yameogo_2001_Chemosphere_42_965 || Sahu_1996_Indian.J.Malariol_33_16 || Yameogo_1991_Ecotoxicol.Environ.Saf_21_248 || Velayudhan_1990_J.Commun.Dis_22_140
    [comment] => 
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 93460
    [family] => ACHE
    [inchikey] => QHGVXILFMXYDRS-UHFFFAOYSA-N
    [canonicalsmiles] => CCCSP(=O)(OCC)OC1=CN(N=C1)C2=CC=C(C=C2)Cl
    [inchi] => InChI=1S\/C14H18ClN2O3PS\/c1-3-9-22-21(18,19-4-2)20-14-10-16-17(11-14)13-7-5-12(15)6-8-13\/h5-8,10-11H,3-4,9H2,1-2H3
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)