PHK

General

Type : Peptide,Halo ketone

Chemical_Nomenclature : (2R,3S)-3-amino-1-chloro-4-phenylbutan-2-ol

Canonical SMILES : C1=CC=C(C=C1)CC(C(CCl)O)N

InChI : InChI=1S\/C10H14ClNO\/c11-7-10(13)9(12)6-8-4-2-1-3-5-8\/h1-5,9-10,13H,6-7,12H2\/t9-,10-\/m0\/s1

InChIKey : YXWOYBQZWSLSMU-UWVGGRQHSA-N

Other name(s) : 3-amino-1-chloro-4-phenyl-butanol-2-yl,phenylalanyl chloromethylketone,PCK,AC1NRCRI,SCHEMBL996512,ZINC12504342,DB04415


MW : 199.67

Formula : C10H14ClNO

CAS_number :

PubChem : 5289149

UniChem : YXWOYBQZWSLSMU-UWVGGRQHSA-N

IUPHAR :

Wikipedia :

Target

Families : PHK ligand of proteins in family: Proline_iminopeptidase

Stucture :

Protein : theac-pip

References (2)

Title : X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum - Goettig_2005_J.Biol.Chem_280_33387
Author(s) : Goettig P , Brandstetter H , Groll M , Gohring W , Konarev PV , Svergun DI , Huber R , Kim JS
Ref : Journal of Biological Chemistry , 280 :33387 , 2005
Abstract : Goettig_2005_J.Biol.Chem_280_33387
ESTHER : Goettig_2005_J.Biol.Chem_280_33387
PubMedSearch : Goettig_2005_J.Biol.Chem_280_33387
PubMedID: 15994304
Gene_locus related to this paper: theac-pip

Title : Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism - Goettig_2002_Embo.J_21_5343
Author(s) : Goettig P , Groll M , Kim JS , Huber R , Brandstetter H
Ref : EMBO Journal , 21 :5343 , 2002
Abstract : Goettig_2002_Embo.J_21_5343
ESTHER : Goettig_2002_Embo.J_21_5343
PubMedSearch : Goettig_2002_Embo.J_21_5343
PubMedID: 12374735
Gene_locus related to this paper: theac-pip