NSPA
IC50 6muM for human-EPHX1
General
Type : Sulfur Compound
Chemical_Nomenclature : 2-nonylsulfanylpropanamide
Canonical SMILES : CCCCCCCCCSC(C)C(=O)N
InChI : InChI=1S\/C12H25NOS\/c1-3-4-5-6-7-8-9-10-15-11(2)12(13)14\/h11H,3-10H2,1-2H3,(H2,13,14)
InChIKey : RZYSYBMLOXBABO-UHFFFAOYSA-N
Other name(s) : 2-nonylsulfanyl-propionamide,CHEMBL3823046,SCHEMBL15335285,BDBM50184992
MW : 231.4
Formula : C12H25NOS
CAS_number :
PubChem : 73897891
UniChem : RZYSYBMLOXBABO-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : NSPA ligand of proteins in family: Epoxide_hydrolase
Stucture :
Protein : mouse-EPHX1 || human-EPHX1
References (2)
| Title : Beyond detoxification: a role for mouse mEH in the hepatic metabolism of endogenous lipids - Marowsky_2017_Arch.Toxicol_91_3571 |
| Author(s) : Marowsky A , Meyer I , Erismann-Ebner K , Pellegrini G , Mule N , Arand M |
| Ref : Archives of Toxicology , 91 :3571 , 2017 |
| Abstract : Marowsky_2017_Arch.Toxicol_91_3571 |
| ESTHER : Marowsky_2017_Arch.Toxicol_91_3571 |
| PubMedSearch : Marowsky_2017_Arch.Toxicol_91_3571 |
| PubMedID: 28975360 |
| Gene_locus related to this paper: mouse-EPHX1 |
| Title : Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase - Morisseau_2008_Chem.Res.Toxicol_21_951 |
| Author(s) : Morisseau C , Newman JW , Wheelock CE , Hill Iii T , Morin D , Buckpitt AR , Hammock BD |
| Ref : Chemical Research in Toxicology , 21 :951 , 2008 |
| Abstract : Morisseau_2008_Chem.Res.Toxicol_21_951 |
| ESTHER : Morisseau_2008_Chem.Res.Toxicol_21_951 |
| PubMedSearch : Morisseau_2008_Chem.Res.Toxicol_21_951 |
| PubMedID: 18363382 |
| Gene_locus related to this paper: human-EPHX1 , ratno-hyep |