Maslinic-acid
Maslinic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as 'orujo' olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants
General
Type : Terpenoid,Natural
Chemical_Nomenclature : (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
Canonical SMILES : CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1)C)C(=O)O)C
InChI : InChI=1S\/C30H48O4\/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7\/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)\/t19-,20+,21-,22+,23-,27-,28+,29+,30-\/m0\/s1
InChIKey : MDZKJHQSJHYOHJ-LLICELPBSA-N
Other name(s) : Maslinic acid,Crategolic acid,Masilinic acid,CHEMBL201515,ZINC4273446,SCHEMBL570425
MW : 472.7
Formula : C30H48O4
CAS_number : 4373-41-5
PubChem : 73659
UniChem : MDZKJHQSJHYOHJ-LLICELPBSA-N
IUPHAR :
Wikipedia :
Target
Families : Maslinic-acid ligand of proteins in family: ABHD12-PHARC
Stucture :
Protein : human-ABHD12
References (1)
| Title : Discovery of Triterpenoids as Reversible Inhibitors of alpha\/beta-hydrolase Domain Containing 12 (ABHD12) - Parkkari_2014_PLoS.One_9_e98286 |
| Author(s) : Parkkari T , Haavikko R , Laitinen T , Navia-Paldanius D , Rytilahti R , Vaara M , Lehtonen M , Alakurtti S , Yli-Kauhaluoma J , Nevalainen T , Savinainen JR , Laitinen JT |
| Ref : PLoS ONE , 9 :e98286 , 2014 |
| Abstract : Parkkari_2014_PLoS.One_9_e98286 |
| ESTHER : Parkkari_2014_PLoS.One_9_e98286 |
| PubMedSearch : Parkkari_2014_PLoS.One_9_e98286 |
| PubMedID: 24879289 |
| Gene_locus related to this paper: human-ABHD12 |