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Inhibitor Report for: ML114

General
Type Thiazolidine, Sulfur Compound
Chemical_Nomenclature [(E)-1-(1,3-thiazol-2-yl)ethylideneamino] cyclohexanecarboxylate
Canonical SMILES CC(=NOC(=O)C1CCCCC1)C2=NC=CS2
InChI InChI=1S/C12H16N2O2S/c1-9(11-13-7-8-17-11)14-16-12(15)10-5-3-2-4-6-10/h7-8,10H,2-6H2,1H3/b14-9+
InChIKey RRXZTDHBRAEGPA-NTEUORMPSA-N
Other name(s) C12H16N2O2S ; CHEMBL1092791 ; SR-01000307014 ; CHEBI:92614 ; BDBM50314727
________________________________________________________________________________________________
MW|252.33
Formula|
CAS_number|
PubChem|5934766
UniChem|RRXZTDHBRAEGPA-NTEUORMPSA-N
IUPHAR|
Wikipedia|

Target
Families | ML114 ligand of proteins in family: Hydrolase_RBBP9_YdeN
Protein | human-RBBP9

References:
Search PubMed for references concerning: ML114
    Title: Application of the RBBP9 Serine Hydrolase Inhibitor, ML114, Decouples Human Pluripotent Stem Cell Proliferation and Differentiation
    Lim S, Shparberg RA, Coorssen JR, O'Connor MD
    Ref: Int J Mol Sci, 21:, 2020 : PubMed

            

    Title: Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)
    Bachovchin DA, Wolfe MR, Masuda K, Brown SJ, Spicer TP, Fernandez-Vega V, Chase P, Hodder PS, Rosen H, Cravatt BF
    Ref: Bioorganic & Medicinal Chemistry Lett, 20:2254, 2010 : PubMed

            

    Title: Probe Report for RBBP9 Inhibitors - Probe 2
    Bachovchin DA, Speers AE, Brown SJ, Cravatt BF, Spicer T, Mercer BA, Ferguson J, Hodder P, Rosen HR
    Ref: Probe Report, :, 2010 : PubMed