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Inhibitor Report for: Imidocarb

Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites. Poor inhibitor of butyrylcholinesterase. Imidocarb dipropionate; 55750-06-6; Imidocarb (dipropionate) is the formulated drug


General
Type Urea derivative, Drug
Chemical_Nomenclature 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea
Canonical SMILES C1CN=C(N1)C2=CC(=CC=C2)NC(=O)NC3=CC=CC(=C3)C4=NCCN4
InChI InChI=1S/C19H20N6O/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26)
InChIKey SCEVFJUWLLRELN-UHFFFAOYSA-N
Other name(s) Imidocarbum ; Imidocarbe ; CHEMBL427342 ; SCHEMBL203921 ; ZINC73661 ; CHEBI:51804 ; Imidocarb dipropionate ; 55750-06-6 ; Imidocarb (dipropionate) ; Imidocarb propionate
________________________________________________________________________________________________
MW|348.4
Formula|C19H20N6O
CAS_number|27885-92-3
PubChem|21389
UniChem|SCEVFJUWLLRELN-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target

References:
Search PubMed for references concerning: Imidocarb

3 more
    Title: Imidocarb dipropionate in the treatment of Anaplasma marginale in cattle: Effects on enzymes of the antioxidant, cholinergic, and adenosinergic systems
    Doyle RL, Fritzen A, Bottari NB, Alves MS, da Silva AD, Morsch VM, Schetinger MR, Martins JR, Santos JS and Da Silva AS <1 more author(s)>
    Ref: Microb Pathog, 97:226, 2016 : PubMed

            

    Title: Effect of induced hypomagnesaemia on the toxicity of imidocarb in calves
    Michell AR, White DG, Higgins AJ, Moss P, Lees P
    Ref: Res Vet Sci, 40:264, 1986 : PubMed

            

    Title: The kinetic constants for the inhibition of acetylcholinesterases by esters of phosphonodithioimidocarbonic acids
    Mehrotra KN, Lal S
    Ref: Indian J Biochem, 7:167, 1970 : PubMed