Diethylene-glycol
Polyethylene glycol (PEG) is a polyether compound with many applications from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG is commonly expressed as H-(O-CH2-CH2)n-OH. The numbers that are often included in the names of PEGs indicate their average molecular weights (e.g. a PEG with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 400.) PEG-200 n =4 190 - 210 g/mol. Diethylene-glycol is the degradation product of hydrolysis of PEG and certain PUR (polyester polyurethane.)
General
Type : Polymer,Poly-ethylene-glycol
Chemical_Nomenclature : 2-(2-hydroxyethoxy)ethanol
Canonical SMILES : C(COCCO)O
InChI : InChI=1S\/C4H10O3\/c5-1-3-7-4-2-6\/h5-6H,1-4H2
InChIKey : MTHSVFCYNBDYFN-UHFFFAOYSA-N
Other name(s) : PEG,2,2'-Oxydiethanol,Diglycol,Diethylenglykol,2-Hydroxyethyl ether
MW : 106.12
Formula : C4H10O3
CAS_number : 111-46-6
PubChem : 8117
UniChem : MTHSVFCYNBDYFN-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : Diethylene-glycol ligand of proteins in family: Hydroxynitrile_lyase || ACHE
Stucture :
Protein : hevbr-hnl || torca-ACHE
References (3)
| Title : The Impact of Crystallization Conditions on Structure-Based Drug Design: A Case Study on the Methylene Blue\/Acetylcholinesterase Complex - Dym_2016_Protein.Sci_25_1096 |
| Author(s) : Dym O , Song W , Felder CE , Roth E , Shnyrov V , Ashani Y , Xu Y , Joosten RP , Weiner L , Sussman JL , Silman I |
| Ref : Protein Science , 25 :1096 , 2016 |
| Abstract : Dym_2016_Protein.Sci_25_1096 |
| ESTHER : Dym_2016_Protein.Sci_25_1096 |
| PubMedSearch : Dym_2016_Protein.Sci_25_1096 |
| PubMedID: 26990888 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A neutral molecule in a cation-binding site: specific binding of a PEG-SH to acetylcholinesterase from Torpedo californica - Koellner_2002_J.Mol.Biol_320_721 |
| Author(s) : Koellner G , Steiner T , Millard CB , Silman I , Sussman JL |
| Ref : Journal of Molecular Biology , 320 :721 , 2002 |
| Abstract : Koellner_2002_J.Mol.Biol_320_721 |
| ESTHER : Koellner_2002_J.Mol.Biol_320_721 |
| PubMedSearch : Koellner_2002_J.Mol.Biol_320_721 |
| PubMedID: 12095250 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica - Koellner_2000_J.Mol.Biol_296_713 |
| Author(s) : Koellner G , Kryger G , Millard CB , Silman I , Sussman JL , Steiner T |
| Ref : Journal of Molecular Biology , 296 :713 , 2000 |
| Abstract : Koellner_2000_J.Mol.Biol_296_713 |
| ESTHER : Koellner_2000_J.Mol.Biol_296_713 |
| PubMedSearch : Koellner_2000_J.Mol.Biol_296_713 |
| PubMedID: 10669619 |