Coelenteramine
General
Type : Luciferin
Chemical_Nomenclature : 4-(5-amino-6-benzylpyrazin-2-yl)phenol
Canonical SMILES : C1=CC=C(C=C1)CC2=NC(=CN=C2N)C3=CC=C(C=C3)O
InChI : InChI=1S\/C17H15N3O\/c18-17-15(10-12-4-2-1-3-5-12)20-16(11-19-17)13-6-8-14(21)9-7-13\/h1-9,11,21H,10H2,(H2,18,19)
InChIKey : BWNPYAKFDUFNND-UHFFFAOYSA-N
Other name(s) : DB04049,CMN,VKB,2-amino-3-benzyl-5-(4-hydroxyphenyl)pyrazine,2-Amino-3-benzyl-5-(p-hydroxyphenyl)pyrazine,AF 350
MW : 277.32
Formula : C17H15N3O
CAS_number : 37156-84-6
UniChem : BWNPYAKFDUFNND-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : Coelenteramine ligand of proteins in family: Haloalkane_dehalogenase-HLD2
Stucture : 7OMO Crystal structure of coelenteramine-bound Renilla reniformis luciferase RLuc8-D120A variant with fully hydrolyzed product
Protein : renre-luc
References (3)
| Title : Catalytic mechanism for Renilla-type luciferases - Schenkmayerova_2023_Nat.Catal_6_23 |
| Author(s) : Schenkmayerova A , Toul M , Pluskal D , Baatallah R , Gagnot G , Pinto GP , Santana VT , Stuchla M , Neugebauer P , Chaiyen P , Damborsky J , Bednar D , Janin YL , Prokop Z , Marek M |
| Ref : Nature Catalysis , 6 :23 , 2023 |
| Abstract : Schenkmayerova_2023_Nat.Catal_6_23 |
| ESTHER : Schenkmayerova_2023_Nat.Catal_6_23 |
| PubMedSearch : Schenkmayerova_2023_Nat.Catal_6_23 |
| PubMedID: |
| Gene_locus related to this paper: 9zzzz-AncHLDRLuc2 , renre-luc |
| Title : Deciphering Enzyme Mechanisms with Engineered Ancestors and Substrate Analogues - Gao_2023_ChemCatChem_15_e202300745 |
| Author(s) : Gao T , Damborsky J , Janin YL , Marek M |
| Ref : ChemCatChem , 15 :e202300745 , 2023 |
| Abstract : Gao_2023_ChemCatChem_15_e202300745 |
| ESTHER : Gao_2023_ChemCatChem_15_e202300745 |
| PubMedSearch : Gao_2023_ChemCatChem_15_e202300745 |
| PubMedID: |
| Gene_locus related to this paper: renre-luc |
| Title : A catalytic mechanism for Renilla-type bioluminescence - Schenkmayerova_2022_Biorxiv__ |
| Author(s) : Schenkmayerova A , Toul M , Pluskal D , Baatallah R , Gagnot G , Pinto GP , Santana VT , Stuchla M , Neugebauer P , Chaiyen P , Damborsky J , Bednar D , Janin YL , Prokop Z , Marek M |
| Ref : Biorxiv , : , 2022 |
| Abstract : Schenkmayerova_2022_Biorxiv__ |
| ESTHER : Schenkmayerova_2022_Biorxiv__ |
| PubMedSearch : Schenkmayerova_2022_Biorxiv__ |
| PubMedID: |
| Gene_locus related to this paper: 9zzzz-AncHLDRLuc2 , renre-luc |