CHMP-S-methyl
can be synthetized as (Sp) or (P-) and (Rp) or (P+) stereoisomers
General
Type : Organophosphate,Sulfur Compound
Chemical_Nomenclature : [methyl(methylsulfanyl)phosphoryl]oxycycloheptane
Canonical SMILES : C[P](=O)(OC1CCCCCC1)SC
InChI : InChI=1S\/C9H19O2PS\/c1-12(10,13-2)11-9-7-5-3-4-6-8-9\/h9H,3-8H2,1-2H3
InChIKey : USEOQBTXEQNYJU-UHFFFAOYSA-N
Other name(s) : Cycloheptyl methyl S-methylphosphonylthioate
MW : 222.29
Formula : C9H19O2PS
CAS_number :
PubChem : 85590434
UniChem : USEOQBTXEQNYJU-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (3)
| Title : Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates - Hosea_1996_Biochemistry_35_10995 |
| Author(s) : Hosea NA , Radic Z , Tsigelny I , Berman HA , Quinn DM , Taylor P |
| Ref : Biochemistry , 35 :10995 , 1996 |
| Abstract : Hosea_1996_Biochemistry_35_10995 |
| ESTHER : Hosea_1996_Biochemistry_35_10995 |
| PubMedSearch : Hosea_1996_Biochemistry_35_10995 |
| PubMedID: 8718893 |
| Title : Chiral reactions of acetylcholinesterase probed with enantiomeric methylphosphonothioates. Noncovalent determinants of enzyme chirality [published erratum appears in J Biol Chem 1989 Nov 25\;264(33):20154] - Berman_1989_J.Biol.Chem_264_3942 |
| Author(s) : Berman HA , Leonard K |
| Ref : Journal of Biological Chemistry , 264 :3942 , 1989 |
| Abstract : Berman_1989_J.Biol.Chem_264_3942 |
| ESTHER : Berman_1989_J.Biol.Chem_264_3942 |
| PubMedSearch : Berman_1989_J.Biol.Chem_264_3942 |
| PubMedID: 2917983 |
| Title : Chiral nature of covalent methylphosphonyl conjugates of acetylcholinesterase - Berman_1989_J.Biol.Chem_264_3951 |
| Author(s) : Berman HA , Decker MM |
| Ref : Journal of Biological Chemistry , 264 :3951 , 1989 |
| Abstract : Berman_1989_J.Biol.Chem_264_3951 |
| ESTHER : Berman_1989_J.Biol.Chem_264_3951 |
| PubMedSearch : Berman_1989_J.Biol.Chem_264_3951 |
| PubMedID: 2917984 |