CHEMBL4076637
General
Type : Sulfur Compound,Sulfonamide
Chemical_Nomenclature : N-(3,4-difluorophenyl)methanesulfonamide
Canonical SMILES : CS(=O)(=O)NC1=CC(=C(C=C1)F)F
InChI : InChI=1S\/C7H7F2NO2S\/c1-13(11,12)10-5-2-3-6(8)7(9)4-5\/h2-4,10H,1H3
InChIKey : CRLGPRNTBCRIBM-UHFFFAOYSA-N
Other name(s) : 8U3,BAS 00627833,AC1LDLO4,ZINC29686
MW : 207.2
Formula : C7H7F2NO2S
CAS_number : 330468-72-9
PubChem : 669158
UniChem : CRLGPRNTBCRIBM-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : CHEMBL4076637 ligand of proteins in family: PAF-Acetylhydrolase
Stucture : 5YE8 The crystal structure of human Lp-PLA2 in complex with a novel inhibitor
Protein : human-PLA2G7
References (1)
| Title : Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2 - Liu_2017_J.Med.Chem_60_10231 |
| Author(s) : Liu Q , Huang F , Yuan X , Wang K , Zou Y , Shen J , Xu Y |
| Ref : Journal of Medicinal Chemistry , 60 :10231 , 2017 |
| Abstract : Liu_2017_J.Med.Chem_60_10231 |
| ESTHER : Liu_2017_J.Med.Chem_60_10231 |
| PubMedSearch : Liu_2017_J.Med.Chem_60_10231 |
| PubMedID: 29193967 |
| Gene_locus related to this paper: human-PLA2G7 |