Benzimidazole-phenyl-azetidine-carboxylate-11d
General
Type : Cannabinoid-Receptor-ligand,Benzimidazole,Carbamate,Carboxamide,Azetidin
Chemical_Nomenclature : 4-((5-(Diethylcarbamoyl)-1-isopentyl-1H-benzo[d]imidazol-2-yl)methyl)phenyl azetidine-1-carboxylate
Canonical SMILES : C1N(CC1)C(OC2=CC=C(C=C2)CC3=NC4C(N3CCC(C)C)CCC(C4)C(N(CC)CC)=O)=O
InChI : InChI=1S\/C28H42N4O3\/c1-5-30(6-2)27(33)22-10-13-25-24(19-22)29-26(32(25)17-14-20(3)4)18-21-8-11-23(12-9-21)35-28(34)31-15-7-16-31\/h8-9,11-12,20,22,24-25H,5-7,10,13-19H2,1-4H3
InChIKey : XDBCRMOYXMHMDA-UHFFFAOYSA-N
Other name(s) :
Target
Families : Benzimidazole-phenyl-azetidine-carboxylate-11d ligand of proteins in family: BCHE
Stucture :
Protein : human-BCHE
References (1)
| Title : Novel benzimidazole-based pseudo-irreversible butyrylcholinesterase inhibitors with neuroprotective activity in an Alzheimer's disease mouse model - Spatz_2022_RSC.Med.Chem_13_944 |
| Author(s) : Spatz P , Zimmermann T , Steinmuller S , Hofmann J , Maurice T , Decker M |
| Ref : RSC Med Chem , 13 :944 , 2022 |
| Abstract : Spatz_2022_RSC.Med.Chem_13_944 |
| ESTHER : Spatz_2022_RSC.Med.Chem_13_944 |
| PubMedSearch : Spatz_2022_RSC.Med.Chem_13_944 |
| PubMedID: 36092149 |