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Inhibitor Report for: Ala(1-naph)-Pro-CN

Ala(1-naph)-Pro-CN is reported to inhibit the putative hydrolase RBBP9 and dipeptidyl-peptidase 4 (DPP4)


General
Type Peptide, Pyrrolidine, Naphthalen
Chemical_Nomenclature (2S)-1-[(2S)-2-amino-3-naphthalen-1-ylpropanoyl]pyrrolidine-2-carbonitrile
Canonical SMILES C1CC(N(C1)C(=O)C(CC2=CC=CC3=CC=CC=C32)N)C#N
InChI InChI=1S/C18H19N3O/c19-12-15-8-4-10-21(15)18(22)17(20)11-14-7-3-6-13-5-1-2-9-16(13)14/h1-3,5-7,9,15,17H,4,8,10-11,20H2/t15-,17-/m0/s1
InChIKey ZVRWNKCHASBEDZ-RDJZCZTQSA-N
Other name(s) GTPL8607
________________________________________________________________________________________________
MW|293.36
Formula|C18H19N3O
CAS_number|
PubChem|74765859
UniChem|ZVRWNKCHASBEDZ-RDJZCZTQSA-N
IUPHAR|8607
Wikipedia|

Target
Families | Ala(1-naph)-Pro-CN ligand of proteins in family: Hydrolase_RBBP9_YdeN, DPP4N_Peptidase_S9
Protein | human-RBBP9, human-DPP4

References:
Search PubMed for references concerning: Ala(1-naph)-Pro-CN
    Title: A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity
    Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH and Golub TR <7 more author(s)>
    Ref: Nat Chemical Biology, 10:656, 2014 : PubMed