6N3Z-4
General
Type : Urea derivative,Trifluoro
Chemical_Nomenclature : N-methyl-4-[4-[[4-(trifluoromethoxy)phenyl]carbamoylamino]cyclohexyl]oxybenzamide
Canonical SMILES : CNC(=O)C1=CC=C(C=C1)OC2CCC(CC2)NC(=O)NC3=CC=C(C=C3)OC(F)(F)F
InChI : InChI=1S\/C22H24F3N3O4\/c1-26-20(29)14-2-8-17(9-3-14)31-18-10-4-15(5-11-18)27-21(30)28-16-6-12-19(13-7-16)32-22(23,24)25\/h2-3,6-9,12-13,15,18H,4-5,10-11H2,1H3,(H,26,29)(H2,27,28,30)
InChIKey : JNPWHXLRBKEIPP-UHFFFAOYSA-N
Other name(s) : CHEMBL2397138,CHEMBL3353249,CHEMBL3895613,SCHEMBL15271834,SCHEMBL15612039,SCHEMBL15612306
MW : 451.44
Formula : C22H24F3N3O4
CAS_number :
PubChem : 60196738
UniChem : JNPWHXLRBKEIPP-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : 6N3Z-4 ligand of proteins in family: Epoxide_hydrolase
Stucture : 6N3Z Crystal structure of an epoxide hydrolase from Trichoderma reesei in complex with 4
Protein : hypjq-g0r7e2
References (1)
| Title : The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors - de Oliveira_2019_Int.J.Biol.Macromol_129_653 |
| Author(s) : de Oliveira GS , Adriani PP , Ribeiro JA , Morisseau C , Hammock BD , Dias MVB , Chambergo FS |
| Ref : Int J Biol Macromol , 129 :653 , 2019 |
| Abstract : de Oliveira_2019_Int.J.Biol.Macromol_129_653 |
| ESTHER : de Oliveira_2019_Int.J.Biol.Macromol_129_653 |
| PubMedSearch : de Oliveira_2019_Int.J.Biol.Macromol_129_653 |
| PubMedID: 30771398 |
| Gene_locus related to this paper: hypjq-g0r7e2 |