6EUL-BY2

General

Type : Carbamate,Derivative of Rivastigmine

Chemical_Nomenclature : [3-[(1R)-1-(dimethylamino)ethyl]-4-hydroxyphenyl] N-ethyl-N-methylcarbamate

Canonical SMILES : CCN(C)C(=O)OC1=CC(=C(C=C1)O)C(C)N(C)C

InChI : InChI=1S\/C14H22N2O3\/c1-6-16(5)14(18)19-11-7-8-13(17)12(9-11)10(2)15(3)4\/h7-10,17H,6H2,1-5H3\/t10-\/m1\/s1

InChIKey : QLWZODGBJZFYGE-SNVBAGLBSA-N

Other name(s) : [3-[(1~{R})-1-(dimethylamino)ethyl]-4-oxidanyl-phenyl] ~{N}-ethyl-~{N}-methyl-carbamate,BY2


MW : 266.34

Formula : C14H22N2O3

CAS_number :

PubChem : 134823960

UniChem : QLWZODGBJZFYGE-SNVBAGLBSA-N

IUPHAR :

Wikipedia :

Target

Families : 6EUL-BY2 ligand of proteins in family: BCHE

Stucture :

Protein : human-BCHE

References (1)

Title : Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model. - Dighe_2019_Commun.Chem_2_35
Author(s) : Dighe SN , De la Mora E , Chan S , Kantham S , McColl G , Miles JA , Veliyath SK , Sreenivas BY , Nassar ZD , Silman I , Sussman JL , Weik M , McGeary RP , Parat MO , Brazzolotto X , Ross BP
Ref : Communications chemistry , 2 :35 , 2019
Abstract : Dighe_2019_Commun.Chem_2_35
ESTHER : Dighe_2019_Commun.Chem_2_35
PubMedSearch : Dighe_2019_Commun.Chem_2_35
PubMedID:
Gene_locus related to this paper: human-BCHE , torca-ACHE