4-methylumbelliferyl-hexylphosphonate
Inhibition by Methyl 4-nitrophenyl hexylphosphonate 6RB0 (Hormone-sensitive_lipase_like 9bact-LAE6) gives the same adduct (methyl hydrogen (R)-hexylphosphonate) on the active serine as 4-methylumbelliferyl-hexylphosphonate 3ICW
General
Type : Organophosphate,Coumarin
Chemical_Nomenclature : 7-[hexyl(methoxy)phosphoryl]oxy-4-methylchromen-2-one
Canonical SMILES : CCCCCCP(=O)(OC)OC1=CC2=C(C=C1)C(=CC(=O)O2)C
InChI : InChI=1S\/C17H23O5P\/c1-4-5-6-7-10-23(19,20-3)22-14-8-9-15-13(2)11-17(18)21-16(15)12-14\/h8-9,11-12H,4-7,10H2,1-3H3
InChIKey : UDTZADITECBVLJ-UHFFFAOYSA-N
Other name(s) : MHH,SCHEMBL1532904,Methyl 4-methylumbelliferyl hexylphosphonate, >=95.0\% (HPLC),4-Methyl-7-[hexyl(methoxy)phosphinyloxy]-2H-1-benzopyran-2-one
MW : 338.34
Formula : C17H23O5P
CAS_number :
PubChem : 87256467
UniChem : UDTZADITECBVLJ-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : 4-methylumbelliferyl-hexylphosphonate ligand of proteins in family: Canar_LipB || Hormone-sensitive_lipase_like
Stucture :
Protein : canar-LipB || pseth-a0a1m6y2k1
References (1)
| Title : Structural redesign of lipase B from Candida antarctica by circular permutation and incremental truncation - Qian_2009_J.Mol.Biol_393_191 |
| Author(s) : Qian Z , Horton JR , Cheng X , Lutz S |
| Ref : Journal of Molecular Biology , 393 :191 , 2009 |
| Abstract : Qian_2009_J.Mol.Biol_393_191 |
| ESTHER : Qian_2009_J.Mol.Biol_393_191 |
| PubMedSearch : Qian_2009_J.Mol.Biol_393_191 |
| PubMedID: 19683009 |
| Gene_locus related to this paper: canar-LipB |