3,4-dihydroxybenzoate

Product of hydrolysis of alyl-3,4-dihydroxybenzic ester. Protocatechuic acid (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants.

General

Type : Benzoate

Chemical_Nomenclature : 3,4-dihydroxybenzoic acid

Canonical SMILES : C1=CC(=C(C=C1C(=O)O)O)O

InChI : InChI=1S\/C7H6O4\/c8-5-2-1-4(7(10)11)3-6(5)9\/h1-3,8-9H,(H,10,11)

InChIKey : YQUVCSBJEUQKSH-UHFFFAOYSA-N

Other name(s) : Protocatechuic acid,4-Carboxy-1,2-dihydroxybenzene,Protocatehuic acid,Benzoic acid, 3,4-dihydroxy-


MW : 154.12

Formula : C7H6O4

CAS_number : 99-50-3

PubChem : 72

UniChem : YQUVCSBJEUQKSH-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : 3,4-dihydroxybenzoate ligand of proteins in family: Tannase_Bact

Stucture : 4J0J tannin acyl hydrolase in complex with ethyl 3,5-dihydroxybenzoate

Protein : lacpl-tanL

References (5)

Title : Alterations of Na+\/K+-ATPase, cholinergic and antioxidant enzymes activity by protocatechuic acid in cadmium-induced neurotoxicity and oxidative stress in Wistar rats - Adefegha_2016_Biomed.Pharmacother_83_559
Author(s) : Adefegha SA , Oboh G , Omojokun OS , Adefegha OM
Ref : Biomed Pharmacother , 83 :559 , 2016
Abstract : Adefegha_2016_Biomed.Pharmacother_83_559
ESTHER : Adefegha_2016_Biomed.Pharmacother_83_559
PubMedSearch : Adefegha_2016_Biomed.Pharmacother_83_559
PubMedID: 27454871

Title : Crystal structure of tannase from lactobacillusplantarum - Ren_2013_J.Mol.Biol_425_2737
Author(s) : Ren B , Wu M , Wang Q , Peng X , Wen H , McKinstry WJ , Chen Q
Ref : Journal of Molecular Biology , 425 :2737 , 2013
Abstract : Ren_2013_J.Mol.Biol_425_2737
ESTHER : Ren_2013_J.Mol.Biol_425_2737
PubMedSearch : Ren_2013_J.Mol.Biol_425_2737
PubMedID: 23648840
Gene_locus related to this paper: lacpl-tanL

Title : Expression, purification, crystallization and preliminary X-ray analysis of tannase from Lactobacillus plantarum. - Wu_2013_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_69_456
Author(s) : Wu M , Peng X , Wen H , Wang Q , Chen Q , McKinstry WJ , Ren B
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 69 :456 , 2013
Abstract : Wu_2013_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_69_456
ESTHER : Wu_2013_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_69_456
PubMedSearch : Wu_2013_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_69_456
PubMedID: 23545659
Gene_locus related to this paper: lacpl-tanL

Title : Effect of methanol extract of Zanthoxylum piperitum leaves and of its compound, protocatechuic acid, on hepatic drug metabolizing enzymes and lipid peroxidation in rats - Hur_2003_Biosci.Biotechnol.Biochem_67_945
Author(s) : Hur JM , Park JG , Yang KH , Park JC , Park JR , Chun SS , Choi JS , Choi JW
Ref : Biosci Biotechnol Biochem , 67 :945 , 2003
Abstract : Hur_2003_Biosci.Biotechnol.Biochem_67_945
ESTHER : Hur_2003_Biosci.Biotechnol.Biochem_67_945
PubMedSearch : Hur_2003_Biosci.Biotechnol.Biochem_67_945
PubMedID: 12834269

Title : Characterization of the protocatechuic acid catabolic gene cluster from Streptomyces sp. strain 2065 - Iwagami_2000_Appl.Environ.Microbiol_66_1499
Author(s) : Iwagami SG , Yang K , Davies J
Ref : Applied Environmental Microbiology , 66 :1499 , 2000
Abstract : Iwagami_2000_Appl.Environ.Microbiol_66_1499
ESTHER : Iwagami_2000_Appl.Environ.Microbiol_66_1499
PubMedSearch : Iwagami_2000_Appl.Environ.Microbiol_66_1499
PubMedID: 10742233
Gene_locus related to this paper: strsp-PCAL