1d-phosphoryl-dihydroacridine
General
Type : Acridine,Derivative of Tacrine
Chemical_Nomenclature : 9-bis(phenylmethoxy)phosphoryl-9,10-dihydroacridine
Canonical SMILES : C1=CC=C(C=C1)COP(=O)(C2C3=CC=CC=C3NC4=CC=CC=C24)OCC5=CC=CC=C5
InChI : InChI=1S\/C27H24NO3P\/c29-32(30-19-21-11-3-1-4-12-21,31-20-22-13-5-2-6-14-22)27-23-15-7-9-17-25(23)28-26-18-10-8-16-24(26)27\/h1-18,27-28H,19-20H2
InChIKey : YKSDYWQADBNXMP-UHFFFAOYSA-N
Other name(s) :
MW : 441.5
Formula : C27H24NO3P
CAS_number :
PubChem : 162398145
UniChem : YKSDYWQADBNXMP-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families :
Stucture :
Protein :
References (1)
| Title : Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit beta-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease - Makhaeva_2023_Front.Pharmacol_14_1219980 |
| Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Timokhina EN , Serebryakova OG , Shchepochkin AV , Averkov MA , Utepova IA , Demina NS , Radchenko EV , Palyulin VA , Fisenko VP , Bachurin SO , Chupakhin ON , Charushin VN , Richardson RJ |
| Ref : Front Pharmacol , 14 :1219980 , 2023 |
| Abstract : Makhaeva_2023_Front.Pharmacol_14_1219980 |
| ESTHER : Makhaeva_2023_Front.Pharmacol_14_1219980 |
| PubMedSearch : Makhaeva_2023_Front.Pharmacol_14_1219980 |
| PubMedID: 37654616 |