Tetranychus urticae (Two-spotted spider mite) CCE04 tetur01g10750 Carboxylic ester hydrolase
CCE04 = T1JSJ6 (corrected with insertion). Overexpression of an alternative allele of carboxyl\/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto-enol acaricide spirodiclofen through sequestration. Hydrolysis of the ester bond gives the spirodiclofen enol which is the active compoud. Spirodiclofen is hydrolysed by CYP39E10 in mites. The ester bond is hydrolysed by esterases in plasma and liver of vertebrates. (Wei et al. 2019
MPSNLILILL LAICANVILS DTTTEGPIVL TRQGAIQGSR VNVSGFVVER FLGIRYGLIP RRFVYSQVNN NSWSGVLDAT KYGSICPQKS SDLPMDEDCL FLNIWRPAMS DPNVTLPVLF WVHGSGYQQG SGAQNSGDLL APYGNMIMVT INYRLRSFGF AFGDENEIQG NQAVSDIIAA LNWVRQNIAF FGGDPSRVTF AGHSAGSMMG SIIPVLTALD DTLYSRLWLI SGVSVNPMFI EDASVSLAKT KLLASKVGCG SDAPGPLTSQ TISCLQTVNV SAILEHDLDF DIKKLGGADY PAFFPTYGTP LIPMPLVQLP KSNPKVRRTT IFNAIHQDEA STFYGYLKPT NKLEAYKMAF DHLSFVKKDV TEAQMQPFFE YYFNDTKDSD PKALRTALAS FITDYTWGCT SLMLSELYST YHSVRFAVFK YVLDKYGKEA RPGGPQHVDE IELYFGEPFM SKPTEVPFNL GTYSEQDKIQ SLRLMKSLAD YVHGKEPDDW PVLKFNSSNP EKEPIVREIN AQDRNVEYSK QHICLEWSKL FEYDITI
| Title : Overexpression of an alternative allele of carboxyl\/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto-enol acaricide spirodiclofen - Wei_2020_Pest.Manag.Sci_76_1142 |
| Author(s) : Wei P , Demaeght P , De Schutter K , Grigoraki L , Labropoulou V , Riga M , Vontas J , Nauen R , Dermauw W , Van Leeuwen T |
| Ref : Pest Manag Sci , 76 :1142 , 2020 |
| Abstract : Wei_2020_Pest.Manag.Sci_76_1142 |
| ESTHER : Wei_2020_Pest.Manag.Sci_76_1142 |
| PubMedSearch : Wei_2020_Pest.Manag.Sci_76_1142 |
| PubMedID: 31583806 |
| Gene_locus related to this paper: tetur-t1jsj6 , tetur-t1jth6 |