rhoer-MLHB

Rhodococcus erythropolis epsilon-lactone hydrolase

Comment

Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone derivatives of dihydrocarvone (4R)-4-isopropenyl-7-methyl-2-oxo-oxepanone and (6R)-6-isopropenyl-3-methyl-2-oxo-oxepanone, and ethyl caproate.

Relationship

Family : Hormone-sensitive_lipase_like

Block : H

Position in NCBI Life Tree : Rhodococcus erythropolis

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MSATDTARAK ELLASLVSMP DATIDDFRAL YEQVCATFEL PDDAQVEPVD ANGADALWVS APGVSADTVA VVVHGGGFTM GSAHGYRELG YRLSKSGNLR ALVVDYRLAP ESPFPAPVDD VVAAYRYARS LDGVENVFLV GDSAGGGIAM SALITLRDAG EQLPDAAVVL SPLVDLAGES PSLVDRAHLD PLPAAVLVNG MGGLYLNGLD VRHPVASPMH GDLTGLPATL VLVGTDEGLH DDSTRLVDKL KAADVEVQLE IGEGLPHIWP IFSFHPDAVA ATDRIGEFLR SHVAAPR

References

Title : Genetic and biochemical characterization of a novel monoterpene epsilon-lactone hydrolase from Rhodococcus erythropolis DCL14 - van der Vlugt-Bergmans_2001_Appl.Environ.Microbiol_67_733
Author(s) : van der Vlugt-Bergmans CJ , van der Werf MJ
Ref : Applied Environmental Microbiology , 67 :733 , 2001
Abstract : van der Vlugt-Bergmans_2001_Appl.Environ.Microbiol_67_733
ESTHER : van der Vlugt-Bergmans_2001_Appl.Environ.Microbiol_67_733
PubMedSearch : van der Vlugt-Bergmans_2001_Appl.Environ.Microbiol_67_733
PubMedID: 11157238
Gene_locus related to this paper: rhoer-MLHB