pig-dpp4
Sus scrofa dipeptidylpeptidase IV (90-286)
Comment
Belongs to peptidase family s9B || Trembl Q866G2 by Weber A., Gerhartz B., Treichel S., Demuth H.-U. differs by 2 aa
Relationship
Molecular evidence
Sequence
Peptide
KTPWKVLLGL LGIAALVTVI TVPVVLLNKG NDAAADSRRT YTLTDYLKST FRVKFYTLQW ISDHEYLYKQ ENNILLFNAE YGNSSIFLEN STFDELGYST NDYSVSPDRQ FILFEYNYVK QWRHSYTASY DIYDLNKRQL ITEERIPNNT QWITWSPVGH KLAYVWNNDI YVKNEPNLSS QRITWTGKEN VIYNGVTDWV YEEEVFSAYS ALWWSPNGTF LAYAQFNDTE VPLIEYSFYS DESLQYPKTV RIPYPKAGAE NPTVKFFVVD TRTLSPNASV TSYQIVPPAS VLIGDHYLCG VTWVTEERIS LQWIRRAQNY SIIDICDYDE STGRWISSVA RQHIEISTTG WVGRFRPAEP HFTSDGNSFY KIISNEEGYK HICHFQTDKS NCTFITKGAW EVIGIEALTS DYLYYISNEH KGMPGGRNLY RIQLNDYTKV TCLSCELNPE RCQYYSASFS NKAKYYQLRC FGPGLPLYTL HSSSSDKELR VLEDNSALDK MLQDVQMPSK KLDVINLHGT KFWYQMILPP HFDKSKKYPL LIEVYAGPCS QKVDTVFRLS WATYLASTEN IIVASFDGRG SGYQGDKIMH AINRRLGTFE VEDQIEATRQ FSKMGFVDDK RIAIWGWSYG GYVTSMVLGA GSGVFKCGIA VAPVSKWEYY DSVYTERYMG LPTPEDNLDY YRNSTVMSRA ENFKQVEYLL IHGTADDNVH FQQSAQLSKA LVDAGVDFQT MWYTDEDHGI ASNMAHQHIY THMSHFLKQC FSLP
References
| Title : Comparative Analysis of Binding Kinetics and Thermodynamics of Dipeptidyl Peptidase-4 Inhibitors and Their Relationship to Structure - Schnapp_2016_J.Med.Chem_59_7466 |
| Author(s) : Schnapp G , Klein T , Hoevels Y , Bakker RA , Nar H |
| Ref : Journal of Medicinal Chemistry , 59 :7466 , 2016 |
| Abstract : Schnapp_2016_J.Med.Chem_59_7466 |
| ESTHER : Schnapp_2016_J.Med.Chem_59_7466 |
| PubMedSearch : Schnapp_2016_J.Med.Chem_59_7466 |
| PubMedID: 27438064 |
| Gene_locus related to this paper: pig-dpp4 |
| Title : Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV - Engel_2006_J.Mol.Biol_355_768 |
| Author(s) : Engel M , Hoffmann T , Manhart S , Heiser U , Chambre S , Huber R , Demuth HU , Bode W |
| Ref : Journal of Molecular Biology , 355 :768 , 2006 |
| Abstract : Engel_2006_J.Mol.Biol_355_768 |
| ESTHER : Engel_2006_J.Mol.Biol_355_768 |
| PubMedSearch : Engel_2006_J.Mol.Biol_355_768 |
| PubMedID: 16330047 |
| Gene_locus related to this paper: pig-dpp4 |
| Title : The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors - Nordhoff_2006_Bioorg.Med.Chem.Lett_16_1744 |
| Author(s) : Nordhoff S , Cerezo-Galvez S , Feurer A , Hill O , Matassa VG , Metz G , Rummey C , Thiemann M , Edwards PJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :1744 , 2006 |
| Abstract : Nordhoff_2006_Bioorg.Med.Chem.Lett_16_1744 |
| ESTHER : Nordhoff_2006_Bioorg.Med.Chem.Lett_16_1744 |
| PubMedSearch : Nordhoff_2006_Bioorg.Med.Chem.Lett_16_1744 |
| PubMedID: 16376544 |
| Gene_locus related to this paper: pig-dpp4 |
| Title : The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism - Engel_2003_Proc.Natl.Acad.Sci.U.S.A_100_5063 |
| Author(s) : Engel M , Hoffmann T , Wagner L , Wermann M , Heiser U , Kiefersauer R , Huber R , Bode W , Demuth HU , Brandstetter H |
| Ref : Proc Natl Acad Sci U S A , 100 :5063 , 2003 |
| Abstract : Engel_2003_Proc.Natl.Acad.Sci.U.S.A_100_5063 |
| ESTHER : Engel_2003_Proc.Natl.Acad.Sci.U.S.A_100_5063 |
| PubMedSearch : Engel_2003_Proc.Natl.Acad.Sci.U.S.A_100_5063 |
| PubMedID: 12690074 |
| Gene_locus related to this paper: pig-dpp4 |
| Title : Assignment of the dipeptidylpeptidase IV (DPP4) gene to pig chromosome 15q21 - Thomsen_1993_Mamm.Genome_4_604 |
| Author(s) : Thomsen PD , Qvist H , Marklund L , Andersson L , Sjostrom H and |
| Ref : Mamm.Genom , 4 :604 , 1993 |
| Abstract : Thomsen_1993_Mamm.Genome_4_604 |
| ESTHER : Thomsen_1993_Mamm.Genome_4_604 |
| PubMedSearch : Thomsen_1993_Mamm.Genome_4_604 |
| PubMedID: 7903569 |
| Gene_locus related to this paper: pig-dpp4 |