pig-EST1

Sus scrofa (Pig) carboxylesterase retinyl ester hydrolase (EC 3.1.1.-) (reh) CES1

Comment

There are at least 6 isoenzyme (may be different genes Q9TS80 PLE1 A5A4F5 PLE3). Isoenzymes of pig-liver esterase reveal striking differences in enantioselectivities Hummel et al. 2007<\/A>. Polyisoprenylated. methylated protein methyl esterase (PMPMEase). Pig liver esterase 5 (PLE5) (pig-a9gyw6<\/A>) is the isoenzyme crystallized (5FV4<\/A>)

Relationship

Family : Carb_B_Chordata

Block : C

Position in NCBI Life Tree : Sus scrofa

Molecular evidence

No mutation

No structure

No kinetic

No disease

No inhibitor

Sequence

Peptide

MWLLPLVLTS LASSATWAGQ PASPPVVDTA QGRVLGKYVS LEGLAQPVAV FLGVPFAKPP LGSLRFAPPQ PAEPWSFVKN TTSYPPMCCQ DPVVEQMTSD LFTNGKERLT LEFSEDCLYL NIYTPADLTK RGRLPVMVWI HGGGLVLGGA PMYDGVVLAA HENVVVVAIQ YRLGIWGFFS TGDEHSRGNW GHLDQVAALH WVQENIANFG GDPGSVTIFG ESAGGESVSV LVLSPLAKNL FHRAISESGV ALTVALVRKD MKAAAKQIAV LAGCKTTTSA VFVHCLRQKS EDELLDLTLK MKFLTLDFHG DQRESHPFLP TVVDGVLLPK MPEEILAEKD FNTVPYIVGI NKQEFGWLLP TMMGFPLSEG KLDQKTATSL LWKSYPIANI PEELTPVATD KYLGGTDDPV KKKDLFLDLM GDVVFGVPSV TVARQHRDAG APTYMYEFQY RPSFSSDKKP KTVIGDHGDE IFSVFGFPLL KGDAPEEEVS LSKTVMKFWA NFARSGNPNG EGLPHWPMYD QEEGYLQIGV NTQAAKRLKG EEVAFWNDLL SKEAAKKPPK IKHAEL

References

Title : Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences - Zhou_2019_Sci.Rep_9_15564
Author(s) : Zhou Q , Xiao Q , Zhang Y , Wang X , Xiao Y , Shi D
Ref : Sci Rep , 9 :15564 , 2019
Abstract : Zhou_2019_Sci.Rep_9_15564
ESTHER : Zhou_2019_Sci.Rep_9_15564
PubMedSearch : Zhou_2019_Sci.Rep_9_15564
PubMedID: 31664043
Gene_locus related to this paper: pig-EST1 , pig-a0a1s6l967

Title : Regioselective ester cleavage of di-(2-ethylhexyl) trimellitates by porcine liver esterase - Hollerer_2018_Toxicol.In.Vitro_47_178
Author(s) : Hollerer C , Becker G , Goen T , Eckert E
Ref : Toxicol In Vitro , 47 :178 , 2018
Abstract : Hollerer_2018_Toxicol.In.Vitro_47_178
ESTHER : Hollerer_2018_Toxicol.In.Vitro_47_178
PubMedSearch : Hollerer_2018_Toxicol.In.Vitro_47_178
PubMedID: 29180039
Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-a0a1s6l948 , pig-a0a1s6l967

Title : Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs - Xiao_2018_Sci.Rep_8_16364
Author(s) : Xiao Q , Zhou Q , Yang L , Tian Z , Wang X , Xiao Y , Shi D
Ref : Sci Rep , 8 :16364 , 2018
Abstract : Xiao_2018_Sci.Rep_8_16364
ESTHER : Xiao_2018_Sci.Rep_8_16364
PubMedSearch : Xiao_2018_Sci.Rep_8_16364
PubMedID: 30397234
Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-PLE1 , pig-a0a1s6l948 , pig-a0a1s6l959 , pig-a0a1s6l967

Title : Third-Generation Sequencing and Analysis of Four Complete Pig Liver Esterase Gene Sequences in Clones Identified by Screening BAC Library - Zhou_2016_PLoS.One_11_e0163295
Author(s) : Zhou Q , Sun W , Liu X , Wang X , Xiao Y , Bi D , Yin J , Shi D
Ref : PLoS ONE , 11 :e0163295 , 2016
Abstract : Zhou_2016_PLoS.One_11_e0163295
ESTHER : Zhou_2016_PLoS.One_11_e0163295
PubMedSearch : Zhou_2016_PLoS.One_11_e0163295
PubMedID: 27695062
Gene_locus related to this paper: pig-EST1 , pig-PLE1 , pig-a0a1s6l948 , pig-a0a1s6l959 , pig-a0a1s6l967

Title : Selective production of 1-monocaprin by porcine liver carboxylesterase-catalyzed esterification: Its enzyme kinetics and catalytic performance - Park_2016_Enzyme.Microb.Technol_82_51
Author(s) : Park KM , Lee JH , Hong SC , Kwon CW , Jo M , Choi SJ , Kim K , Chang PS
Ref : Enzyme Microb Technol , 82 :51 , 2016
Abstract : Park_2016_Enzyme.Microb.Technol_82_51
ESTHER : Park_2016_Enzyme.Microb.Technol_82_51
PubMedSearch : Park_2016_Enzyme.Microb.Technol_82_51
PubMedID: 26672448
Gene_locus related to this paper: pig-EST1

Title : Inhibition of porcine liver carboxylesterase by phosphorylated flavonoids - Wei_2013_Chem.Biol.Interact_204_75
Author(s) : Wei Y , Peng AY , Huang J
Ref : Chemico-Biological Interactions , 204 :75 , 2013
Abstract : Wei_2013_Chem.Biol.Interact_204_75
ESTHER : Wei_2013_Chem.Biol.Interact_204_75
PubMedSearch : Wei_2013_Chem.Biol.Interact_204_75
PubMedID: 23643881
Gene_locus related to this paper: pig-EST1

Title : Characterization and optimization of carboxylesterase-catalyzed esterification between capric acid and glycerol for the production of 1-monocaprin in reversed micellar system - Park_2010_N.Biotechnol_27_46
Author(s) : Park KM , Kwon OT , Ahn SM , Lee J , Chang PS
Ref : N Biotechnol , 27 :46 , 2010
Abstract : Park_2010_N.Biotechnol_27_46
ESTHER : Park_2010_N.Biotechnol_27_46
PubMedSearch : Park_2010_N.Biotechnol_27_46
PubMedID: 19931658
Gene_locus related to this paper: pig-EST1

Title : Porcine Liver Carboxylesterase Requires Polyisoprenylation for High Affinity Binding to Cysteinyl Substrates - Lamango_2009_Open.Enzym.Inhib.J_2_12
Author(s) : Lamango NS , Duverna R , Zhang W , Ablordeppey SY
Ref : Open Enzym Inhib J , 2 :12 , 2009
Abstract : Lamango_2009_Open.Enzym.Inhib.J_2_12
ESTHER : Lamango_2009_Open.Enzym.Inhib.J_2_12
PubMedSearch : Lamango_2009_Open.Enzym.Inhib.J_2_12
PubMedID: 20664805
Gene_locus related to this paper: pig-EST1

Title : Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase - Oboh_2008_J.Biochem.Mol.Toxicol_22_51
Author(s) : Oboh OT , Lamango NS
Ref : J Biochem Mol Toxicol , 22 :51 , 2008
Abstract : Oboh_2008_J.Biochem.Mol.Toxicol_22_51
ESTHER : Oboh_2008_J.Biochem.Mol.Toxicol_22_51
PubMedSearch : Oboh_2008_J.Biochem.Mol.Toxicol_22_51
PubMedID: 18273909
Gene_locus related to this paper: pig-EST1

Title : Inhibition of porcine liver carboxylesterase by a new flavone glucoside isolated from Deverra scoparia - Djeridane_2008_Chem.Biol.Interact_172_22
Author(s) : Djeridane A , Brunel JM , Vidal N , Yousfi M , Ajandouz EH , Stocker P
Ref : Chemico-Biological Interactions , 172 :22 , 2008
Abstract : Djeridane_2008_Chem.Biol.Interact_172_22
ESTHER : Djeridane_2008_Chem.Biol.Interact_172_22
PubMedSearch : Djeridane_2008_Chem.Biol.Interact_172_22
PubMedID: 18163984
Gene_locus related to this paper: pig-EST1

Title : Isoenzymes of pig-liver esterase reveal striking differences in enantioselectivities -
Author(s) : Hummel A , Brusehaber E , Bottcher D , Trauthwein H , Doderer K , Bornscheuer UT
Ref : Angew Chem Int Ed Engl , 46 :8492 , 2007
PubMedID: 17902087
Gene_locus related to this paper: pig-EST1

Title : Nucleoside ester prodrug substrate specificity of liver carboxylesterase - Landowski_2006_J.Pharmacol.Exp.Ther_316_572
Author(s) : Landowski CP , Lorenzi PL , Song X , Amidon GL
Ref : Journal of Pharmacology & Experimental Therapeutics , 316 :572 , 2006
Abstract : Landowski_2006_J.Pharmacol.Exp.Ther_316_572
ESTHER : Landowski_2006_J.Pharmacol.Exp.Ther_316_572
PubMedSearch : Landowski_2006_J.Pharmacol.Exp.Ther_316_572
PubMedID: 16223870
Gene_locus related to this paper: pig-EST1

Title : Phenolic extracts from various Algerian plants as strong inhibitors of porcine liver carboxylesterase - Djeridane_2006_J.Enzyme.Inhib.Med.Chem_21_719
Author(s) : Djeridane A , Yousfi M , Nadjemi B , Maamri S , Djireb F , Stocker P
Ref : J Enzyme Inhib Med Chem , 21 :719 , 2006
Abstract : Djeridane_2006_J.Enzyme.Inhib.Med.Chem_21_719
ESTHER : Djeridane_2006_J.Enzyme.Inhib.Med.Chem_21_719
PubMedSearch : Djeridane_2006_J.Enzyme.Inhib.Med.Chem_21_719
PubMedID: 17252945
Gene_locus related to this paper: pig-EST1

Title : Purification and molecular cloning of porcine intestinal glycerol-ester hydrolase--evidence for its identity with carboxylesterase - David_1998_Eur.J.Biochem_257_142
Author(s) : David L , Guo XJ , Villard C , Moulin A , Puigserver A
Ref : European Journal of Biochemistry , 257 :142 , 1998
Abstract : David_1998_Eur.J.Biochem_257_142
ESTHER : David_1998_Eur.J.Biochem_257_142
PubMedSearch : David_1998_Eur.J.Biochem_257_142
PubMedID: 9799112
Gene_locus related to this paper: pig-EST1

Title : Purification and characterization of retinyl ester hydrolase as a member of the non-specific carboxylesterase supergene family - Schindler_1998_Eur.J.Biochem_251_863
Author(s) : Schindler R , Mentlein R , Feldheim W
Ref : European Journal of Biochemistry , 251 :863 , 1998
Abstract : Schindler_1998_Eur.J.Biochem_251_863
ESTHER : Schindler_1998_Eur.J.Biochem_251_863
PubMedSearch : Schindler_1998_Eur.J.Biochem_251_863
PubMedID: 9490062
Gene_locus related to this paper: human-CES1 , pig-EST1

Title : Purification, cloning, and expression of a human enzyme with acyl coenzyme A: cholesterol acyltransferase activity, which is identical to liver carboxylesterase - Becker_1994_Arterioscler.Thromb_14_1346
Author(s) : Becker A , Bottcher A , Lackner KJ , Fehringer P , Notka F , Aslanidis C , Schmitz G
Ref : Arterioscler Thromb , 14 :1346 , 1994
Abstract : Becker_1994_Arterioscler.Thromb_14_1346
ESTHER : Becker_1994_Arterioscler.Thromb_14_1346
PubMedSearch : Becker_1994_Arterioscler.Thromb_14_1346
PubMedID: 8049197
Gene_locus related to this paper: human-CES1 , pig-EST1

Title : A note on the identity of porcine liver carboxylesterase and prolyl-beta-naphthylamidase - Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033
Author(s) : Heymann E , Peter K
Ref : Biol Chem Hoppe Seyler , 374 :1033 , 1993
Abstract : Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033
ESTHER : Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033
PubMedSearch : Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033
PubMedID: 8292262
Gene_locus related to this paper: pig-EST1

Title : The nucleotide and deduced amino acid sequences of porcine liver proline- beta-naphthylamidase. Evidence for the identity with carboxylesterase - Matsushima_1991_FEBS.Lett_293_37
Author(s) : Matsushima M , Inoue H , Ichinose M , Tsukada S , Miki K , Kurokawa K , Takahashi T , Takahashi K
Ref : FEBS Letters , 293 :37 , 1991
Abstract : Matsushima_1991_FEBS.Lett_293_37
ESTHER : Matsushima_1991_FEBS.Lett_293_37
PubMedSearch : Matsushima_1991_FEBS.Lett_293_37
PubMedID: 1959668
Gene_locus related to this paper: pig-EST1

Title : [Studies on the demonstration of an alkaline group in the active center of porcine liver carboxylesterase] -
Author(s) : Heymann E , Krisch K
Ref : Hoppe-Seylers Zeitschrift fur physiologische Chemie , 353 :715 , 1972
PubMedID: 4672135
Gene_locus related to this paper: pig-EST1