Mus musculus (Mouse) (peroxisomal cytosolic Acyl-CoA thioesterase Ic)
The mouse ACOT gene cluster comprises six genes with localizations in cytosol (ACOT1), mitochondria (ACOT2), and peroxisomes (ACOT3-6). The corresponding human gene cluster contains only three genes (ACOT1, ACOT2, and ACOT4) coding for full-length thioesterase proteins only ACOT4 is peroxisomal
MVPTVSLEPT GHSCWDEPLS IAVRGLAPEQ PVTLRTALRD EKGALFRAHA RYRADSHGEL DLARTPALGG SFSGLEPMGL LWAMEPDRPF WRLIKRDVQT PFVVELEVLD GHEPDGGRLL ARAVHECHFM APGVRRVPVR EGRVRATLFL PPGTGPFPGI IDLFGVGGGL LEYRASLLAG KGFAVMALAY YKYDDLPKVI DILHLEYFEE AVTYLLSHPQ VKGPGVGLLG ISKGAELSLS MASFLKGITA AVVINGATVN VISTLYYKEE SLPGLGMHLE RIKVTKDGFK DIIDILNVPL EAPDQKSLIP LERSDTAFLF LVGQDDHNWK SEFYAREASK RLQAHGKEKP QIVCYPKTGH HIEPPYIPWS IAAPHSYFDK PILLGGEPRA HAMAQVDAWQ RLQTFFHKHL SGDKRPSPAK L
| Title : Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs - Hunt_2006_FASEB.J_20_1855 |
| Author(s) : Hunt MC , Rautanen A , Westin MA , Svensson LT , Alexson SE |
| Ref : FASEB Journal , 20 :1855 , 2006 |
| Abstract : Hunt_2006_FASEB.J_20_1855 |
| ESTHER : Hunt_2006_FASEB.J_20_1855 |
| PubMedSearch : Hunt_2006_FASEB.J_20_1855 |
| PubMedID: 16940157 |
| Gene_locus related to this paper: human-ACOT1 , human-ACOT2 , human-ACOT4 , human-ACOT6 , mouse-acot1 , mouse-acot2 , mouse-acot3 , mouse-acot4 , mouse-acot5 , mouse-ACOT6 |
| Title : Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases - Westin_2004_J.Biol.Chem_279_21841 |
| Author(s) : Westin MA , Alexson SE , Hunt MC |
| Ref : Journal of Biological Chemistry , 279 :21841 , 2004 |
| Abstract : Westin_2004_J.Biol.Chem_279_21841 |
| ESTHER : Westin_2004_J.Biol.Chem_279_21841 |
| PubMedSearch : Westin_2004_J.Biol.Chem_279_21841 |
| PubMedID: 15007068 |
| Gene_locus related to this paper: mouse-acot3 , mouse-acot5 |