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human-PPT2

Homo sapiens (Human) 34.9 kda protein (palmitoyl-protein thioesterase-2)

Comment

A second form inactive is known Trembl 014799 genbank AF020544 differs by yhe C-terminal end

Relationship

Family : Palmitoyl-protein_thioesterase

Block : X

Position in NCBI Life Tree : Homo sapiens

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MLGLWGQRLP AAWVLLLLPF LPLLLLAAPA PHRASYKPVI VVHGLFDSSY SFRHLLEYIN ETHPGTVVTV LDLFDGRESL RPLWEQVQGF REAVVPIMAK APQGVHLICY SQGGLVCRAL LSVMDDHNVD SFISLSSPQM GQYGDTDYLK WLFPTSMRSN LYRICYSPWG QEFSICNYWH DPHHDDLYLN ASSFLALING ERDHPNATVW RKNFLRVGHL VLIGGPDDGV ITPWQSSFFG FYDANETVLE MEEQLVYLRD SFGLKTLLAR GAIVRCPMAG ISHTAWHSNR TLYETCIEPW LS

References

Title : The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2 - Calero_2003_J.Biol.Chem_278_37957
Author(s) : Calero G , Gupta P , Nonato MC , Tandel S , Biehl ER , Hofmann SL , Clardy J
Ref : Journal of Biological Chemistry , 278 :37957 , 2003
Abstract : Calero_2003_J.Biol.Chem_278_37957
ESTHER : Calero_2003_J.Biol.Chem_278_37957
PubMedSearch : Calero_2003_J.Biol.Chem_278_37957
PubMedID: 12855696
Gene_locus related to this paper: human-PPT2

Title : Characterization of a human MHC class III region gene product with S-thioesterase activity - Aguado_1999_Biochem.J_341 ( Pt 3)_679
Author(s) : Aguado B , Campbell RD
Ref : Biochemical Journal , 341 ( Pt 3) :679 , 1999
Abstract : Aguado_1999_Biochem.J_341 ( Pt 3)_679
ESTHER : Aguado_1999_Biochem.J_341 ( Pt 3)_679
PubMedSearch : Aguado_1999_Biochem.J_341 ( Pt 3)_679
PubMedID: 10417332
Gene_locus related to this paper: human-PPT2

Title : Structure of the human palmitoyl-protein thioesterase-2 gene (PPT2) in the major histocompatibility complex on chromosome 6p21.3 - Soyombo_1999_Genomics_56_208
Author(s) : Soyombo AA , Yi W , Hofmann SL
Ref : Genomics , 56 :208 , 1999
Abstract : Soyombo_1999_Genomics_56_208
ESTHER : Soyombo_1999_Genomics_56_208
PubMedSearch : Soyombo_1999_Genomics_56_208
PubMedID: 10051407
Gene_locus related to this paper: human-PPT2

Title : Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity - Soyombo_1997_J.Biol.Chem_272_27456
Author(s) : Soyombo AA , Hofmann SL
Ref : Journal of Biological Chemistry , 272 :27456 , 1997
Abstract : Soyombo_1997_J.Biol.Chem_272_27456
ESTHER : Soyombo_1997_J.Biol.Chem_272_27456
PubMedSearch : Soyombo_1997_J.Biol.Chem_272_27456
PubMedID: 9341199
Gene_locus related to this paper: human-PPT2