Homo sapiens (Human) Candidate tumor suppressor in ovarian cancer
human-OVCA2 Human Candidate tumor suppressor in ovarian cancer and yeast-FSH3 regulated by the Crt1 transcription factor, an effector of the DNA damage checkpoint pathway in Saccharomyces cerevisiae, may be involved in folate metabolism. OVCA2 has a strong preference for long-chain alkyl ester substrates (>10-carbons) and high selectivity against a variety of short, branched, and substituted esters Bun et al. 2020
MAAQRPLRVL CLAGFRQSER GFREKTGALR KALRGRAELV CLSGPHPVPD PPGPEGARSD FGSCPPEEQP RGWWFSEQEA DVFSALEEPA VCRGLEESLG MVAQALNRLG PFDGLLGFSQ GAALAALVCA LGQAGDPRFP LPRFILLVSG FCPRGIGFKE SILQRPLSLP SLHVFGDTDK VIPSQESVQL ASQFPGAITL THSGGHFIPA AAPQRQAYLK FLDQFAE
| Title : Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae - Bun_2020_PLoS.One_15_e0230166 |
| Author(s) : Bun JS , Slack MD , Schemenauer DE , Johnson RJ |
| Ref : PLoS ONE , 15 :e0230166 , 2020 |
| Abstract : Bun_2020_PLoS.One_15_e0230166 |
| ESTHER : Bun_2020_PLoS.One_15_e0230166 |
| PubMedSearch : Bun_2020_PLoS.One_15_e0230166 |
| PubMedID: 32182256 |
| Gene_locus related to this paper: human-OVCA2 , yeast-FSH1 |
| Title : Mass spectrometric identification of serine hydrolase OVCA2 in the medulloblastoma cell line DAOY - Azizi_2006_Cancer.Lett_241_235 |
| Author(s) : Azizi AA , Gelpi E , Yang JW , Rupp B , Godwin AK , Slater C , Slavc I , Lubec G |
| Ref : Cancer Letters , 241 :235 , 2006 |
| Abstract : Azizi_2006_Cancer.Lett_241_235 |
| ESTHER : Azizi_2006_Cancer.Lett_241_235 |
| PubMedSearch : Azizi_2006_Cancer.Lett_241_235 |
| PubMedID: 16368187 |
| Gene_locus related to this paper: human-OVCA2 |
| Title : OVCA2 is downregulated and degraded during retinoid-induced apoptosis - Prowse_2002_Int.J.Cancer_99_185 |
| Author(s) : Prowse AH , Vanderveer L , Milling SW , Pan ZZ , Dunbrack RL , Xu XX , Godwin AK |
| Ref : International Journal of Cancer , 99 :185 , 2002 |
| Abstract : Prowse_2002_Int.J.Cancer_99_185 |
| ESTHER : Prowse_2002_Int.J.Cancer_99_185 |
| PubMedSearch : Prowse_2002_Int.J.Cancer_99_185 |
| PubMedID: 11979432 |
| Gene_locus related to this paper: human-OVCA2 |
| Title : Identification of two candidate tumor suppressor genes on chromosome 17p13.3 - Schultz_1996_Cancer.Res_56_1997 |
| Author(s) : Schultz DC , Vanderveer L , Berman DB , Hamilton TC , Wong AJ , Godwin AK |
| Ref : Cancer Research , 56 :1997 , 1996 |
| Abstract : Schultz_1996_Cancer.Res_56_1997 |
| ESTHER : Schultz_1996_Cancer.Res_56_1997 |
| PubMedSearch : Schultz_1996_Cancer.Res_56_1997 |
| PubMedID: 8616839 |
| Gene_locus related to this paper: human-OVCA2 |