Culex pipiens acetylcholinesterase (Northern house mosquito) Culex quinquefasciatus (Southern house mosquito) (Culex pungens)(ache1 gene)
This gene is duplicated independently in many strains Labb et al. AJ489456 is mRNA of the strain SLAB and AJ515147 is for the resistant G119S SR strain. genbank accession numbers AJ512688 to AJ512717 are partial sequences of different strain of the Culex pipiens complex (C.pip.pip. and C.pip.quinq) || Partial sequence from this gene found in 14 other mosquitos Aedes albopictus (Forest day mosquito) AJ438598 Anopheles albimanus (New world malaria mosquito) AJ438608 Anopheles arabiensis (Mosquito) AJ438603 Anopheles darlingi AJ438599Anopheles funestus AJ438604 Anopheles minimus AJ438601 Anopheles moucheti AJ438602 Anopheles nili AJ438609 Anopheles pseudopunctipennis AJ438605 Anopheles sacharovi AJ438606 Anopheles stephensi (Indo-Pakistan malaria mosquito) AJ438607Anopheles sundaicus AJ438600 and ACES_CULP\; Culex pipiens pipiens (Northern house mosquito) NCBI_TaxID 38569 ACES_CULQU Q867X2\; Q867X1\; Q867X4 Q1WKR8 Culex quinquefasciatus (Southern house mosquito).\;ACES_CULTO Q86GC9 Culex torrentium (Mosquito) NCBI_TaxID=42433 || Culex pipiens pallens Q5XL61_CULPI acetylcholinesterase (EC 3.1.1.7) by Li et al. 2004 identical except for a 9 aa deletion in N-term || In Culex quinquefasciatus Q1WKR8 is for Gongdi-S Q1WKR9 is for Gongdi-R The G119S mutation
MEIRGLITRL LGPCHLRHLI LCSLGLYSIL VQSVHCRHHD IGSSVAHQLG SKYSQSSSLS SSSQSSSSLA EEATLNKDSD AFFTPYIGHG DSVRIVDAEL GTLEREHIHS TTTRRRGLTR RESSSDATDS DPLVITTDKG KIRGTTLEAP SGKKVDAWMG IPYAQPPLGP LRFRHPRPAE RWTGVLNATK PPNSCVQIVD TVFGDFPGAT MWNPNTPLSE DCLYINVVVP RPRPKNAAVM LWIFGGGFYS GTATLDVYDH RTLASEENVI VVSLQYRVAS LGFLFLGTPE APGNAGLFDQ NLALRWVRDN IHRFGGDPSR VTLFGESAGA VSVSLHLLSA LSRDLFQRAI LQSGSPTAPW ALVSREEATL RALRLAEAVN CPHDATKLSD AVECLRTKDP NELVDNEWGT LGICEFPFVP VVDGAFLDET PQRSLASGRF KKTDILTGSN TEEGYYFIIY YLTELLRKEE GVTVTREEFL QAVRELNPYV NGAARQAIVF EYTDWIEPDN PNSNRDALDK MVGDYHFTCN VNEFAQRYAE EGNNVFMYLY THRSKGNPWP RWTGVMHGDE INYVFGEPLN SALGYQDDEK DFSRKIMRYW SNFAKTGNPN PSTPSVDLPE WPKHTAHGRH YLELGLNTTF VGRGPRLRQC AFWKKYLPQL VAATSNLQVT PAPSVPCESS STSYRSTLLL IVTLLLVTRF KI
Title : The evolutionary fate of heterogeneous gene duplications: A precarious overdominant equilibrium between environment, sublethality and complementation - Milesi_2018_Mol.Ecol_27_493 |
Author(s) : Milesi P , Assogba BS , Atyame CM , Pocquet N , Berthomieu A , Unal S , Makoundou P , Weill M , Labbe P |
Ref : Mol Ecol , 27 :493 , 2018 |
Abstract : Milesi_2018_Mol.Ecol_27_493 |
ESTHER : Milesi_2018_Mol.Ecol_27_493 |
PubMedSearch : Milesi_2018_Mol.Ecol_27_493 |
PubMedID: 29230902 |
Gene_locus related to this paper: culpi-ACHE1 , culqu-ACHE1 |
Title : Point Mutations Associated with Organophosphate and Carbamate Resistance in Chinese Strains of Culex pipiens quinquefasciatus (Diptera: Culicidae) - Zhao_2014_PLoS.One_9_e952607 |
Author(s) : Zhao M , Dong Y , Ran X , Wu Z , Guo X , Zhang Y , Xing D , Yan T , Wang G , Zhu X , Zhang H , Li C , Zhao T |
Ref : PLoS ONE , 9 :e95260 , 2014 |
Abstract : Zhao_2014_PLoS.One_9_e952607 |
ESTHER : Zhao_2014_PLoS.One_9_e952607 |
PubMedSearch : Zhao_2014_PLoS.One_9_e952607 |
PubMedID: 24788312 |
Gene_locus related to this paper: culpi-ACHE1 |
Title : First molecular genotyping of insensitive acetylcholinesterase associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia - Low_2013_Pest.Manag.Sci_69_1362 |
Author(s) : Low VL , Chen CD , Lim PE , Lee HL , Lim YA , Tan TK , Sofian-Azirun M |
Ref : Pest Manag Sci , 69 :1362 , 2013 |
Abstract : Low_2013_Pest.Manag.Sci_69_1362 |
ESTHER : Low_2013_Pest.Manag.Sci_69_1362 |
PubMedSearch : Low_2013_Pest.Manag.Sci_69_1362 |
PubMedID: 23404830 |
Gene_locus related to this paper: culpi-ACHE1 |
Title : Susceptibility status of Culex quinquefasciatus (Diptera: Culicidae) populations to the chemical insecticide temephos in Pernambuco, Brazil - Amorim_2013_Pest.Manag.Sci_69_1307 |
Author(s) : Amorim LB , Helvecio E , de Oliveira CM , Ayres CF |
Ref : Pest Manag Sci , 69 :1307 , 2013 |
Abstract : Amorim_2013_Pest.Manag.Sci_69_1307 |
ESTHER : Amorim_2013_Pest.Manag.Sci_69_1307 |
PubMedSearch : Amorim_2013_Pest.Manag.Sci_69_1307 |
PubMedID: 23576326 |
Gene_locus related to this paper: culpi-ACHE1 |
Title : Insecticide resistance to organophosphates in Culex pipiens complex from Lebanon - Osta_2012_Parasit.Vectors_5_132 |
Author(s) : Osta MA , Rizk ZJ , Labbe P , Weill M , Knio K |
Ref : Parasit Vectors , 5 :132 , 2012 |
Abstract : Osta_2012_Parasit.Vectors_5_132 |
ESTHER : Osta_2012_Parasit.Vectors_5_132 |
PubMedSearch : Osta_2012_Parasit.Vectors_5_132 |
PubMedID: 22759898 |
Gene_locus related to this paper: culpi-ACHE1 |
Title : Independent duplications of the acetylcholinesterase gene conferring insecticide resistance in the mosquito Culex pipiens - Labbe_2007_Mol.Biol.Evol_24_1056 |
Author(s) : Labbe P , Berthomieu A , Berticat C , Alout H , Raymond M , Lenormand T , Weill M |
Ref : Molecular Biology Evolution , 24 :1056 , 2007 |
Abstract : Labbe_2007_Mol.Biol.Evol_24_1056 |
ESTHER : Labbe_2007_Mol.Biol.Evol_24_1056 |
PubMedSearch : Labbe_2007_Mol.Biol.Evol_24_1056 |
PubMedID: 17283366 |
Gene_locus related to this paper: culpi-ACHE1 , culqu-ACHE1 |
Title : A new amino-acid substitution in acetylcholinesterase 1 confers insecticide resistance to Culex pipiens mosquitoes from Cyprus - Alout_2007_Insect.Biochem.Mol.Biol_37_41 |
Author(s) : Alout H , Berthomieu A , Hadjivassilis A , Weill M |
Ref : Insect Biochemistry & Molecular Biology , 37 :41 , 2007 |
Abstract : Alout_2007_Insect.Biochem.Mol.Biol_37_41 |
ESTHER : Alout_2007_Insect.Biochem.Mol.Biol_37_41 |
PubMedSearch : Alout_2007_Insect.Biochem.Mol.Biol_37_41 |
PubMedID: 17175445 |
Gene_locus related to this paper: culpi-ACHE1 |
Title : Different amino-acid substitutions confer insecticide resistance through acetylcholinesterase 1 insensitivity in Culex vishnui and Culex tritaeniorhynchus (Diptera: Culicidae) from China - Alout_2007_J.Med.Entomol_44_463 |
Author(s) : Alout H , Berthomieu A , Cui F , Tan Y , Berticat C , Qiao C , Weill M |
Ref : Journal of Medical Entomology , 44 :463 , 2007 |
Abstract : Alout_2007_J.Med.Entomol_44_463 |
ESTHER : Alout_2007_J.Med.Entomol_44_463 |
PubMedSearch : Alout_2007_J.Med.Entomol_44_463 |
PubMedID: 17547232 |
Gene_locus related to this paper: culpi-ACHE1 |
Title : Recent emergence of insensitive acetylcholinesterase in Chinese populations of the mosquito Culex pipiens (Diptera: Culicidae) - Cui_2006_J.Med.Entomol_43_878 |
Author(s) : Cui F , Raymond M , Berthomieu A , Alout H , Weill M , Qiao CL |
Ref : Journal of Medical Entomology , 43 :878 , 2006 |
Abstract : Cui_2006_J.Med.Entomol_43_878 |
ESTHER : Cui_2006_J.Med.Entomol_43_878 |
PubMedSearch : Cui_2006_J.Med.Entomol_43_878 |
PubMedID: 17017223 |
Gene_locus related to this paper: culpi-ACHE1 |
Title : Acetylcholinesterase genes within the Diptera: takeover and loss in true flies - Huchard_2006_Proc.Biol.Sci_273_2595 |
Author(s) : Huchard E , Martinez M , Alout H , Douzery EJ , Lutfalla G , Berthomieu A , Berticat C , Raymond M , Weill M |
Ref : Proc Biol Sci , 273 :2595 , 2006 |
Abstract : Huchard_2006_Proc.Biol.Sci_273_2595 |
ESTHER : Huchard_2006_Proc.Biol.Sci_273_2595 |
PubMedSearch : Huchard_2006_Proc.Biol.Sci_273_2595 |
PubMedID: 17002944 |
Gene_locus related to this paper: culpi-ACHE1 , culpi-ACHE2 , drobs-ACHE2 , drosi-ACHE , drowi-ACHE , gloff-ACHE2 |
Title : The unique mutation in ace-1 giving high insecticide resistance is easily detectable in mosquito vectors - Weill_2004_Insect.Mol.Biol_13_1 |
Author(s) : Weill M , Malcolm C , Chandre F , Mogensen K , Berthomieu A , Marquine M , Raymond M |
Ref : Insect Molecular Biology , 13 :1 , 2004 |
Abstract : Weill_2004_Insect.Mol.Biol_13_1 |
ESTHER : Weill_2004_Insect.Mol.Biol_13_1 |
PubMedSearch : Weill_2004_Insect.Mol.Biol_13_1 |
PubMedID: 14728661 |
Gene_locus related to this paper: anoga-ACHE1 , culpi-ACHE1 |
Title : Cloning of culex pipiens pallens cDNA encoding acetylcholinesterase and homology modeling of ache. - |
Author(s) : Li CX , Zhao TY , Dong YD |
Ref : Ji Sheng Chong Yu Yi Xue Kun Chong Xue Bao , 11 :161 , 2004 |
PubMedID: |
Gene_locus related to this paper: culpi-ACHE1 |
Title : Comparative genomics: Insecticide resistance in mosquito vectors - Weill_2003_Nature_423_136 |
Author(s) : Weill M , Lutfalla G , Mogensen K , Chandre F , Berthomieu A , Berticat C , Pasteur N , Philips A , Fort P , Raymond M |
Ref : Nature , 423 :136 , 2003 |
Abstract : Weill_2003_Nature_423_136 |
ESTHER : Weill_2003_Nature_423_136 |
PubMedSearch : Weill_2003_Nature_423_136 |
PubMedID: 12736674 |
Gene_locus related to this paper: anoga-ACHE1 , culpi-ACHE1 |
Title : A novel acetylcholinesterase gene in mosquitoes codes for the insecticide target and is non-homologous to the ace gene Drosophila - Weill_2002_Proc.R.Soc.Lond.B.Biol.Sci_269_2007 |
Author(s) : Weill M , Fort P , Berthomieu A , Dubois MP , Pasteur N , Raymond M |
Ref : Proc R Soc Lond B Biol Sci , 269 :2007 , 2002 |
Abstract : Weill_2002_Proc.R.Soc.Lond.B.Biol.Sci_269_2007 |
ESTHER : Weill_2002_Proc.R.Soc.Lond.B.Biol.Sci_269_2007 |
PubMedSearch : Weill_2002_Proc.R.Soc.Lond.B.Biol.Sci_269_2007 |
PubMedID: 12396499 |
Gene_locus related to this paper: aedae-ACHE1 , anoga-ACHE1 , anoga-ACHE2 , cioin-ACHE1 , ciosa-ACHE , culpi-ACHE1 |