Bos taurus (Bovine); Bos mutus (wild yak) Abhydrolase domain containing 16B
Other strains: Bos taurus (Bovine)\; Bos mutus (wild yak) || Shan et al.<\/A> identified a nonsense mutation in the bovine Abhydrolase domain containing 16B gene ABHD16B (SNP rs468948776 AC_000170 g.54429815G>A) associated with male subfertility in Holstein cattle. The mutation causes a premature stop codon at amino acid position Glu 218, resulting in a truncation of 235 C-terminal amino acids. ABHD16B is involved in lipid biosynthesis in testis and is crucial for fertilization
MCVVCFVKAL VHVFKIYLTA NYTYNFRGWP VDFRWDDVRA AAGSGSSHRA LTCAAAAAGV WLLRGAALGE DSPVRLPRAA RSQAQCLLQQ IRELPSQLAS YALAHSLGRW LVYPGSMFLM TRALLPLLQQ GQERLVERYR GRRAKLVACD GNEIDTMFMD RRQDPGSHGR GLRLVICCEG NAGFYEMGCL SAPLEAGYSV LGWNHPGFGG STGAPFPQHD ANAMDVVVKY ALHRLHFPPA HVVVYGWSIG GFTATWATMT YPELGALVLD ATFDDLVPLA LKVMPHSWKG LVVRTVREHF NLNVAEQLCR YPGPVLLLRR TQDDVVSTAG HLRPLPSGVV EGNRGNELLL RLLQHRYPAV MAREGLAIVT RWLRAGSLAQ EAAFYARYRV DDEWCLSLLR SYLTHCEDQQ EDEETWGSHG LAFPWLVGQG LSPRRRRQLA LFLARKHLKN VEATHCSPLE PEDFQLPWRL
| Title : alpha\/beta-Hydrolase D16B Truncation Results in Premature Sperm Capacitation in Cattle - Shan_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Shan S , Xu F , Hirschfeld M , Herrmann C , Schulze M , Sharifi AR , Hoelker M , Brenig B |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : Shan_2022_Int.J.Mol.Sci_23_ |
| ESTHER : Shan_2022_Int.J.Mol.Sci_23_ |
| PubMedSearch : Shan_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 35887122 |
| Gene_locus related to this paper: bovin-ABHD16B , human-ABHD16B |
| Title : Association of alpha\/beta-Hydrolase D16B with Bovine Conception Rate and Sperm Plasma Membrane Lipid Composition - Shan_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Shan S , Xu F , Bleyer M , Becker S , Melbaum T , Wemheuer W , Hirschfeld M , Wacker C , Zhao S , Schutz E , Brenig B |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : Shan_2020_Int.J.Mol.Sci_21_ |
| ESTHER : Shan_2020_Int.J.Mol.Sci_21_ |
| PubMedSearch : Shan_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 31963602 |
| Gene_locus related to this paper: bovin-ABHD16B , human-ABHD16B , mouse-Abhd16b |