arath-At5g14930
Arabidopsis thaliana (Mouse-ear cress) At5g14930 sag101 AtSAG101
Comment
The Arabidopsis EDS1 (arath-eds1) and PAD4 (arath-pad4 F22O6.190) genes encode lipase-like proteins that function in resistance (R) gene-mediated and basal plant disease resistance.EDS1 can dimerize and interact with PAD4 or with SAG101 (arath-At5g14930). Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors to detect pathogen effectors and activate local and systemic defence. NRG1 and ADR1 'helper' NLRs (RNLs) cooperate with enhanced disease susceptibility 1 (EDS1), senescence-associated gene 101 (SAG101) and phytoalexin-deficient 4 (PAD4) lipase-like proteins to mediate signalling from TIR domain NLR receptors (TNLs). Two distinct modules (NRG1\/EDS1\/SAG101 and ADR1\/EDS1\/PAD4) mediate TNL receptor defence signalling.
Relationship
Sequence
Peptide
MIRVYKFQKK KDSGLEFQIH REEKFTLVVF SAPPICRSSS SDSTLLHVKD KENPFPFLCS ENNPSFSLHT PAFNLFTSAP TSLTYLKSEL LQTLKSEKPV IITGAALGGS VASLYTLWLL ETIEPTLKRP LCITFGSPLI GDASLQQILE NSVRNSCFLH VVSAQTRIKM DFFKPFGTFL ICFDSGCVCI EDHVAVTELL NGVHDSGLVD YSQVLNRLDQ SMLSLADSRL IPEDVIKGIE KRAEMKNLRF DMMFKKLNDM KISMAYIEWY KKKCKEVKIG YYDRFKTQLA FPSKEFDINI KNHHKSELNR FWKSVVEEVE RRPQSDASIL KRRFLFSGNN YRRMIEPLDI AEYYLEGRKE YRTMGRSHHY VMLEKWFGME SILIEKERCK KRDLSDLLTF DSCFWAEVED SLIVINQLNT TVGMRDDERE VLTRKLVEFE GYVWEIITKR EVSPEIFLEE SSFMKWWKEY KKIKGFNSSY LTEFMNTRKY ESYGKSQ
References
| Title : Cavity surface residues of PAD4 and SAG101 contribute to EDS1 dimer signaling specificity in plant immunity - Dongus_2022_Plant.J__ |
| Author(s) : Dongus JA , Bhandari DD , Penner E , Lapin D , Stolze SC , Harzen A , Patel M , Archer L , Dijkgraaf L , Shah J , Nakagami H , Parker JE |
| Ref : Plant J , : , 2022 |
| Abstract : Dongus_2022_Plant.J__ |
| ESTHER : Dongus_2022_Plant.J__ |
| PubMedSearch : Dongus_2022_Plant.J__ |
| PubMedID: 35324052 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity - Sun_2021_Nat.Commun_12_3335 |
| Author(s) : Sun X , Lapin D , Feehan JM , Stolze SC , Kramer K , Dongus JA , Rzemieniewski J , Blanvillain-Baufume S , Harzen A , Bautor J , Derbyshire P , Menke FLH , Finkemeier I , Nakagami H , Jones JDG , Parker JE |
| Ref : Nat Commun , 12 :3335 , 2021 |
| Abstract : Sun_2021_Nat.Commun_12_3335 |
| ESTHER : Sun_2021_Nat.Commun_12_3335 |
| PubMedSearch : Sun_2021_Nat.Commun_12_3335 |
| PubMedID: 34099661 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : A Coevolved EDS1-SAG101-NRG1 Module Mediates Cell Death Signaling by TIR-Domain Immune Receptors - Lapin_2019_Plant.Cell_31_2430 |
| Author(s) : Lapin D , Kovacova V , Sun X , Dongus JA , Bhandari D , von Born P , Bautor J , Guarneri N , Rzemieniewski J , Stuttmann J , Beyer A , Parker JE |
| Ref : Plant Cell , 31 :2430 , 2019 |
| Abstract : Lapin_2019_Plant.Cell_31_2430 |
| ESTHER : Lapin_2019_Plant.Cell_31_2430 |
| PubMedSearch : Lapin_2019_Plant.Cell_31_2430 |
| PubMedID: 31311833 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity - Wagner_2013_Cell.Host.Microbe_14_619 |
| Author(s) : Wagner S , Stuttmann J , Rietz S , Guerois R , Brunstein E , Bautor J , Niefind K , Parker JE |
| Ref : Cell Host Microbe , 14 :619 , 2013 |
| Abstract : Wagner_2013_Cell.Host.Microbe_14_619 |
| ESTHER : Wagner_2013_Cell.Host.Microbe_14_619 |
| PubMedSearch : Wagner_2013_Cell.Host.Microbe_14_619 |
| PubMedID: 24331460 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : Crystallization and preliminary crystallographic analysis of Arabidopsis thaliana EDS1, a key component of plant immunity, in complex with its signalling partner SAG101 - Wagner_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_245 |
| Author(s) : Wagner S , Rietz S , Parker JE , Niefind K |
| Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 67 :245 , 2011 |
| Abstract : Wagner_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_245 |
| ESTHER : Wagner_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_245 |
| PubMedSearch : Wagner_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_245 |
| PubMedID: 21301097 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity - Feys_2005_Plant.Cell_17_2601 |
| Author(s) : Feys BJ , Wiermer M , Bhat RA , Moisan LJ , Medina-Escobar N , Neu C , Cabral A , Parker JE |
| Ref : Plant Cell , 17 :2601 , 2005 |
| Abstract : Feys_2005_Plant.Cell_17_2601 |
| ESTHER : Feys_2005_Plant.Cell_17_2601 |
| PubMedSearch : Feys_2005_Plant.Cell_17_2601 |
| PubMedID: 16040633 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 , arath-T17F15.50 |
| Title : A gene encoding an acyl hydrolase is involved in leaf senescence in Arabidopsis - He_2002_Plant.Cell_14_805 |
| Author(s) : He Y , Gan S |
| Ref : Plant Cell , 14 :805 , 2002 |
| Abstract : He_2002_Plant.Cell_14_805 |
| ESTHER : He_2002_Plant.Cell_14_805 |
| PubMedSearch : He_2002_Plant.Cell_14_805 |
| PubMedID: 11971136 |
| Gene_locus related to this paper: arath-At5g14930 |
| Title : Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones. - |
| Author(s) : Asamizu E , Sato S , Kaneko T , Nakamura Y , Kotani H , Miyajima N , Tabata S |
| Ref : DNA Research , 5 :379 , 1998 |
| PubMedID: 10048488 |
| Gene_locus related to this paper: arath-At5g14930 , arath-at5g18630 , arath-AT5G19050 , arath-At5g24180 , arath-AT5G24190 , arath-At5g24200 , arath-F2G14.100 , arath-F6H11.120 , arath-F9G14.280 , arath-F14F8.240 , arath-HNL , arath-At5g14310 |