Lyngbya majuscula 19L Polyketide synthase
only a little C-terminal 1979-2036 part homologous to ab-hydrolases. || In Gu et al. the sequence is corrected because Q6DNE0 may have been partially replaced with exogenous DNA during construction of the genomic library
MEEKFLEFGG NQICLCSWGS PEHPVVLCIH GILEQGLAWQ EVALPLAAQG YRVVAPDLFG HGRSSHLEMV TSYSSLTFLA QIDRVIQELP DQPLLLVGHS MGAMLATAIA SVRPKKIKEL ILVELPLPAE ESKKESAVNQ LTTCLDYLSS TPQHPIFPDV ATAASRLRQA IPSLSEEFSY ILAQRITQPN QGGVRWSWDA IIRTRSILGL NNLPGGRSQY LEMLKSIQVP TTLVYGDSSK LNRPEDLQQQ KMTMTQAKRV FLSGGHNLHI DAAAALASLI LTS
Title : Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase - Gehret_2011_J.Biol.Chem_286_14445 |
Author(s) : Gehret JJ , Gu L , Gerwick WH , Wipf P , Sherman DH , Smith JL |
Ref : Journal of Biological Chemistry , 286 :14445 , 2011 |
Abstract : Gehret_2011_J.Biol.Chem_286_14445 |
ESTHER : Gehret_2011_J.Biol.Chem_286_14445 |
PubMedSearch : Gehret_2011_J.Biol.Chem_286_14445 |
PubMedID: 21357626 |
Gene_locus related to this paper: 9cyan-d0e8e2 |
Title : Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis - Gu_2009_J.Am.Chem.Soc_131_16033 |
Author(s) : Gu L , Wang B , Kulkarni A , Gehret JJ , Lloyd KR , Gerwick L , Gerwick WH , Wipf P , Hakansson K , Smith JL , Sherman DH |
Ref : Journal of the American Chemical Society , 131 :16033 , 2009 |
Abstract : Gu_2009_J.Am.Chem.Soc_131_16033 |
ESTHER : Gu_2009_J.Am.Chem.Soc_131_16033 |
PubMedSearch : Gu_2009_J.Am.Chem.Soc_131_16033 |
PubMedID: 19835378 |
Gene_locus related to this paper: 9cyan-d0e8e2 |
Title : Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula - Chang_2004_J.Nat.Prod_67_1356 |
Author(s) : Chang Z , Sitachitta N , Rossi JV , Roberts MA , Flatt PM , Jia J , Sherman DH , Gerwick WH |
Ref : Journal of Natural Products , 67 :1356 , 2004 |
Abstract : Chang_2004_J.Nat.Prod_67_1356 |
ESTHER : Chang_2004_J.Nat.Prod_67_1356 |
PubMedSearch : Chang_2004_J.Nat.Prod_67_1356 |
PubMedID: 15332855 |
Gene_locus related to this paper: 9cyan-d0e8e2 , 9cyan-q6dnd9 |