Plasmodium_subtelomeric_PST-A
Relationship
Comment
These proteins represent a paralogous family of genes found in Plasmodium falciparum and Plasmodium yoelii that are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii. TIGRFAMs TIGR01607 (PST-A). Close sequences of other Apicomplexa species were includedDatabase
Interpro : IPR006494 Plasmodium subtelomeric PST-A PST_A
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF12146 Hydrolase_4
Prints : No Print
EC Number : No EC Number
References (1)
| Title : The Antimalarial Natural Product Salinipostin A Identifies Essential alpha\/beta Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites - Yoo_2020_Cell.Chem.Biol_27_143 |
| Author(s) : Yoo E , Schulze CJ , Stokes BH , Onguka O , Yeo T , Mok S , Gnadig NF , Zhou Y , Kurita K , Foe IT , Terrell SM , Boucher MJ , Cieplak P , Kumpornsin K , Lee MCS , Linington RG , Long JZ , Uhlemann AC , Weerapana E , Fidock DA , Bogyo M |
| Ref : Cell Chemical Biology , 27 :143 , 2020 |
| Abstract : Yoo_2020_Cell.Chem.Biol_27_143 |
| ESTHER : Yoo_2020_Cell.Chem.Biol_27_143 |
| PubMedSearch : Yoo_2020_Cell.Chem.Biol_27_143 |
| PubMedID: 31978322 |
| Gene_locus related to this paper: plaf7-q8ii19 , plafa-a0a143zya4 , plaf7-q8iik5 , plafa-MAL8P1.38 , plafa-PF07.0040 , plafa-PF10.0020 , plafa-PF10.0379 , plafa-PF13.0153 |
No structure scheme yet for this family
Genes Proteins in Plasmodium_subtelomeric_PST-A family (56)
Fragments of genes in Plasmodium_subtelomeric_PST-A family (3)
No fragment of genesSubstrates in Plasmodium_subtelomeric_PST-A family (3)
Inhibitors in Plasmodium_subtelomeric_PST-A family (6)