Interpro : IPR000952 Uncharacterised protein family UPF0017, hydrolase-like, conserved site , IPR012020 AB hydrolase 4 family, AB-hydrolase YheT, putative ABHD4 , IPR000952 UPF0017_hydro-like_CS
PIRSF : PIRSF005211 Ab_hydro_YheT
Pdoc : PDOC00872
Pfam : No Pfam
Prints : No Print
EC Number : No EC Number
Title : Lipidomic QTL in Diversity Outbred mice identifies a novel function for alpha\/beta hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin - Price_2023_bioRxiv__ |
Author(s) : Price TR , Stapleton DS , Schueler KL , Norris MK , Parks BW , Yandell BS , Churchill GA , Holland WL , Keller MP , Attie AD |
Ref : Biorxiv , : , 2023 |
Abstract : Price_2023_bioRxiv__ |
ESTHER : Price_2023_bioRxiv__ |
PubMedSearch : Price_2023_bioRxiv__ |
PubMedID: 36993241 |
Gene_locus related to this paper: human-ABHD2 , mouse-ABHD2 |
Title : Progesterone activates the cyclic AMP-protein kinase A signalling pathway by upregulating ABHD2 in fertile men - Jiang_2021_J.Int.Med.Res_49_300060521999527 |
Author(s) : Jiang F , Zhu Y , Chen Y , Tang X , Liu L , Chen G , Liu Y , Sun X |
Ref : J Internal Medicine Res , 49 :300060521999527 , 2021 |
Abstract : Jiang_2021_J.Int.Med.Res_49_300060521999527 |
ESTHER : Jiang_2021_J.Int.Med.Res_49_300060521999527 |
PubMedSearch : Jiang_2021_J.Int.Med.Res_49_300060521999527 |
PubMedID: 33752482 |
Gene_locus related to this paper: human-ABHD2 |
Title : Alpha\/Beta Hydrolase Domain-Containing Protein 2 regulates the rhythm of follicular maturation and estrous stages of the female reproductive cycle - Bjorkgren_2021_Front.Cell.Dev.Biol_9_710864 |
Author(s) : Bjorkgren I , Chung DH , Mendoza S , Gabelev-Khasin L , Modzelewski A , He L , Lishko PV |
Ref : Front Cell Developmental Biology , 9 :710864 , 2021 |
Abstract : Bjorkgren_2021_Front.Cell.Dev.Biol_9_710864 |
ESTHER : Bjorkgren_2021_Front.Cell.Dev.Biol_9_710864 |
PubMedSearch : Bjorkgren_2021_Front.Cell.Dev.Biol_9_710864 |
PubMedID: 34568325 |
Gene_locus related to this paper: human-ABHD2 , mouse-ABHD2 |
Title : miR-140-3p Inhibits Cutaneous Melanoma Progression by Disrupting AKT\/p70S6K and JNK Pathways through ABHD2 - He_2020_Mol.Ther.Oncolytics_17_83 |
Author(s) : He Y , Yang Y , Liao Y , Xu J , Liu L , Li C , Xiong X |
Ref : Mol Ther Oncolytics , 17 :83 , 2020 |
Abstract : He_2020_Mol.Ther.Oncolytics_17_83 |
ESTHER : He_2020_Mol.Ther.Oncolytics_17_83 |
PubMedSearch : He_2020_Mol.Ther.Oncolytics_17_83 |
PubMedID: 32322665 |
Gene_locus related to this paper: human-ABHD2 |
Title : A large-scale genome-lipid association map guides lipid identification - Linke_2020_Nat.Metab_2_1149 |
Author(s) : Linke V , Overmyer KA , Miller IJ , Brademan DR , Hutchins PD , Trujillo EA , Reddy TR , Russell JD , Cushing EM , Schueler KL , Stapleton DS , Rabaglia ME , Keller MP , Gatti DM , Keele GR , Pham D , Broman KW , Churchill GA , Attie AD , Coon JJ |
Ref : Nat Metab , 2 :1149 , 2020 |
Abstract : Linke_2020_Nat.Metab_2_1149 |
ESTHER : Linke_2020_Nat.Metab_2_1149 |
PubMedSearch : Linke_2020_Nat.Metab_2_1149 |
PubMedID: 32958938 |
Gene_locus related to this paper: human-ABHD1 , human-ABHD3 |
Title : Retinoic Acid Induces Differentiation of Mouse F9 Embryonic Carcinoma Cell by Modulating the miR-485 Targeting of Abhd2 - Yu_2019_Int.J.Mol.Sci_20_ |
Author(s) : Yu M , Zhang L , Liu Y , Liu D , Guo Z |
Ref : Int J Mol Sci , 20 : , 2019 |
Abstract : Yu_2019_Int.J.Mol.Sci_20_ |
ESTHER : Yu_2019_Int.J.Mol.Sci_20_ |
PubMedSearch : Yu_2019_Int.J.Mol.Sci_20_ |
PubMedID: 31035455 |
Gene_locus related to this paper: human-ABHD2 |
Title : ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation - Stockli_2019_Mol.Metab_25_83 |
Author(s) : Stockli J , Zadoorian A , Cooke KC , Deshpande V , Yau B , Herrmann G , Kebede MA , Humphrey SJ , James DE |
Ref : Mol Metab , 25 :83 , 2019 |
Abstract : Stockli_2019_Mol.Metab_25_83 |
ESTHER : Stockli_2019_Mol.Metab_25_83 |
PubMedSearch : Stockli_2019_Mol.Metab_25_83 |
PubMedID: 31105056 |
Gene_locus related to this paper: human-ABHD15 , mouse-ABH15 |
Title : ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction - Baggelaar_2019_ACS.Chem.Biol_14_2295 |
Author(s) : Baggelaar MP , den Dulk H , Florea BI , Fazio D , Perruzza D , Bernabo N , Raspa M , Janssen APA , Scavizzi F , Barboni B , Overkleeft HS , Maccarrone M , van der Stelt M |
Ref : ACS Chemical Biology , 14 :2295 , 2019 |
Abstract : Baggelaar_2019_ACS.Chem.Biol_14_2295 |
ESTHER : Baggelaar_2019_ACS.Chem.Biol_14_2295 |
PubMedSearch : Baggelaar_2019_ACS.Chem.Biol_14_2295 |
PubMedID: 31525885 |
Gene_locus related to this paper: human-ABHD2 , human-ABHD3 |
Title : Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance - Xia_2018_Cell.Rep_23_1948 |
Author(s) : Xia W , Pessentheiner AR , Hofer DC , Amor M , Schreiber R , Schoiswohl G , Eichmann TO , Walenta E , Itariu B , Prager G , Hackl H , Stulnig T , Kratky D , Rulicke T , Bogner-Strauss JG |
Ref : Cell Rep , 23 :1948 , 2018 |
Abstract : Xia_2018_Cell.Rep_23_1948 |
ESTHER : Xia_2018_Cell.Rep_23_1948 |
PubMedSearch : Xia_2018_Cell.Rep_23_1948 |
PubMedID: 29768196 |
Gene_locus related to this paper: human-ABHD15 , mouse-ABH15 |
Title : Regulation of the sperm calcium channel CatSper by endogenous steroids and plant triterpenoids - Mannowetz_2017_Proc.Natl.Acad.Sci.U.S.A_114_5743 |
Author(s) : Mannowetz N , Miller MR , Lishko PV |
Ref : Proc Natl Acad Sci U S A , 114 :5743 , 2017 |
Abstract : Mannowetz_2017_Proc.Natl.Acad.Sci.U.S.A_114_5743 |
ESTHER : Mannowetz_2017_Proc.Natl.Acad.Sci.U.S.A_114_5743 |
PubMedSearch : Mannowetz_2017_Proc.Natl.Acad.Sci.U.S.A_114_5743 |
PubMedID: 28507119 |
Gene_locus related to this paper: human-ABHD2 |
Title : Regulation of calcium release from the endoplasmic reticulum by the serine hydrolase ABHD2 - Yun_2017_Biochem.Biophys.Res.Commun_490_1226 |
Author(s) : Yun B , Lee H , Powell R , Reisdorph N , Ewing H , Gelb MH , Hsu KL , Cravatt BF , Leslie CC |
Ref : Biochemical & Biophysical Research Communications , 490 :1226 , 2017 |
Abstract : Yun_2017_Biochem.Biophys.Res.Commun_490_1226 |
ESTHER : Yun_2017_Biochem.Biophys.Res.Commun_490_1226 |
PubMedSearch : Yun_2017_Biochem.Biophys.Res.Commun_490_1226 |
PubMedID: 28684316 |
Gene_locus related to this paper: human-ABHD2 |
Title : Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes - Rondini_2017_J.Pharmacol.Exp.Ther_363_367 |
Author(s) : Rondini EA , Mladenovic-Lucas L , Roush WR , Halvorsen GT , Green AE , Granneman JG |
Ref : Journal of Pharmacology & Experimental Therapeutics , 363 :367 , 2017 |
Abstract : Rondini_2017_J.Pharmacol.Exp.Ther_363_367 |
ESTHER : Rondini_2017_J.Pharmacol.Exp.Ther_363_367 |
PubMedSearch : Rondini_2017_J.Pharmacol.Exp.Ther_363_367 |
PubMedID: 28928121 |
Gene_locus related to this paper: human-ABHD5 , mouse-abhd5 |
Title : Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone - Miller_2016_Science_352_555 |
Author(s) : Miller MR , Mannowetz N , Iavarone AT , Safavi R , Gracheva EO , Smith JF , Hill RZ , Bautista DM , Kirichok Y , Lishko PV |
Ref : Science , 352 :555 , 2016 |
Abstract : Miller_2016_Science_352_555 |
ESTHER : Miller_2016_Science_352_555 |
PubMedSearch : Miller_2016_Science_352_555 |
PubMedID: 26989199 |
Gene_locus related to this paper: human-ABHD2 |
Title : Associations of ABHD2 Genetic Variations with Risks for Chronic Obstructive Pulmonary Disease in a Chinese Han Population - Liu_2015_PLoS.One_10_e0123929 |
Author(s) : Liu L , Li X , Yuan R , Zhang H , Qiang L , Shen J , Jin S |
Ref : PLoS ONE , 10 :e0123929 , 2015 |
Abstract : Liu_2015_PLoS.One_10_e0123929 |
ESTHER : Liu_2015_PLoS.One_10_e0123929 |
PubMedSearch : Liu_2015_PLoS.One_10_e0123929 |
PubMedID: 25880496 |
Gene_locus related to this paper: human-ABHD2 |
Title : The yeast enzyme Eht1 is an octanoyl-CoA:ethanol acyltransferase that also functions as a thioesterase - Knight_2014_Yeast_31_463 |
Author(s) : Knight MJ , Bull ID , Curnow P |
Ref : Yeast , 31 :463 , 2014 |
Abstract : Knight_2014_Yeast_31_463 |
ESTHER : Knight_2014_Yeast_31_463 |
PubMedSearch : Knight_2014_Yeast_31_463 |
PubMedID: 25308280 |
Gene_locus related to this paper: yeast-MCFS2 |
Title : alpha\/beta-Hydrolase Domain Containing Protein 15 (ABHD15) - an Adipogenic Protein Protecting from Apoptosis - Walenta_2013_PLoS.One_8_e79134 |
Author(s) : Walenta E , Pessentheiner AR , Pelzmann HJ , Deutsch A , Goeritzer M , Kratky D , Hackl H , Oh da Y , Prokesch A , Bogner-Strauss JG |
Ref : PLoS ONE , 8 :e79134 , 2013 |
Abstract : Walenta_2013_PLoS.One_8_e79134 |
ESTHER : Walenta_2013_PLoS.One_8_e79134 |
PubMedSearch : Walenta_2013_PLoS.One_8_e79134 |
PubMedID: 24236098 |
Gene_locus related to this paper: human-ABHD15 |
Title : Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids - Long_2011_Nat.Chem.Biol_7_763 |
Author(s) : Long JZ , Cisar JS , Milliken D , Niessen S , Wang C , Trauger SA , Siuzdak G , Cravatt BF |
Ref : Nat Chemical Biology , 7 :763 , 2011 |
Abstract : Long_2011_Nat.Chem.Biol_7_763 |
ESTHER : Long_2011_Nat.Chem.Biol_7_763 |
PubMedSearch : Long_2011_Nat.Chem.Biol_7_763 |
PubMedID: 21926997 |
Gene_locus related to this paper: human-ABHD3 , mouse-abhd3 |
Title : Age-related pulmonary emphysema in mice lacking alpha\/beta hydrolase domain containing 2 gene - Jin_2009_Biochem.Biophys.Res.Commun_380_419 |
Author(s) : Jin S , Zhao G , Li Z , Nishimoto Y , Isohama Y , Shen J , Ito T , Takeya M , Araki K , He P , Yamamura K |
Ref : Biochemical & Biophysical Research Communications , 380 :419 , 2009 |
Abstract : Jin_2009_Biochem.Biophys.Res.Commun_380_419 |
ESTHER : Jin_2009_Biochem.Biophys.Res.Commun_380_419 |
PubMedSearch : Jin_2009_Biochem.Biophys.Res.Commun_380_419 |
PubMedID: 19250629 |
Gene_locus related to this paper: human-ABHD2 , mouse-ABHD2 |
Title : Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque - Miyata_2008_Biochem.Biophys.Res.Commun_365_207 |
Author(s) : Miyata K , Nakayama M , Mizuta S , Hokimoto S , Sugamura K , Oshima S , Oike Y , Sugiyama S , Ogawa H , Yamamura K |
Ref : Biochemical & Biophysical Research Communications , 365 :207 , 2008 |
Abstract : Miyata_2008_Biochem.Biophys.Res.Commun_365_207 |
ESTHER : Miyata_2008_Biochem.Biophys.Res.Commun_365_207 |
PubMedSearch : Miyata_2008_Biochem.Biophys.Res.Commun_365_207 |
PubMedID: 17980156 |
Gene_locus related to this paper: human-ABHD2 , mouse-ABHD2 |
Title : The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity - Saerens_2006_J.Biol.Chem_281_4446 |
Author(s) : Saerens SM , Verstrepen KJ , Van Laere SD , Voet AR , Van Dijck P , Delvaux FR , Thevelein JM |
Ref : Journal of Biological Chemistry , 281 :4446 , 2006 |
Abstract : Saerens_2006_J.Biol.Chem_281_4446 |
ESTHER : Saerens_2006_J.Biol.Chem_281_4446 |
PubMedSearch : Saerens_2006_J.Biol.Chem_281_4446 |
PubMedID: 16361250 |
Gene_locus related to this paper: yeast-MCFS1 , yeast-MCFS2 , yeast-ym60 |
Title : Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha\/beta hydrolase domain containing 2 gene - Miyata_2005_Biochem.Biophys.Res.Commun_329_296 |
Author(s) : Miyata K , Oike Y , Hoshii T , Maekawa H , Ogawa H , Suda T , Araki K , Yamamura K |
Ref : Biochemical & Biophysical Research Communications , 329 :296 , 2005 |
Abstract : Miyata_2005_Biochem.Biophys.Res.Commun_329_296 |
ESTHER : Miyata_2005_Biochem.Biophys.Res.Commun_329_296 |
PubMedSearch : Miyata_2005_Biochem.Biophys.Res.Commun_329_296 |
PubMedID: 15721306 |
Gene_locus related to this paper: human-ABHD2 , mouse-ABHD2 |
Title : Alpha\/beta hydrolase2, a predicated gene adjacent to mad in Drosophila melanogaster, belongs to a new global multigene family and is associated with obesity - Wisotzkey_2003_J.Mol.Evol_56_351 |
Author(s) : Wisotzkey RG , Johnson AN , Takaesu NT , Newfeld SJ |
Ref : Journal of Molecular Evolution , 56 :351 , 2003 |
Abstract : Wisotzkey_2003_J.Mol.Evol_56_351 |
ESTHER : Wisotzkey_2003_J.Mol.Evol_56_351 |
PubMedSearch : Wisotzkey_2003_J.Mol.Evol_56_351 |
PubMedID: 12612838 |
Gene_locus related to this paper: drome-abhd2 |
Title : Cloning and characterization of six embryogenesis-associated cDNAs from somatic embryos of Picea glauca and their comparative expression during zygotic embryogenesis - Dong_1999_Plant.Mol.Biol_39_859 |
Author(s) : Dong JZ , Dunstan DI |
Ref : Plant Mol Biol , 39 :859 , 1999 |
Abstract : Dong_1999_Plant.Mol.Biol_39_859 |
ESTHER : Dong_1999_Plant.Mol.Biol_39_859 |
PubMedSearch : Dong_1999_Plant.Mol.Biol_39_859 |
PubMedID: 10350098 |
Gene_locus related to this paper: picgl-emb8 |
Title : Functional analysis of the Escherichia coli genome for members of the alpha\/beta hydrolase family - Zhang_1998_Fold.Des_3_535 |
Author(s) : Zhang L , Godzik A , Skolnick J , Fetrow JS |
Ref : Fold Des , 3 :535 , 1998 |
Abstract : Zhang_1998_Fold.Des_3_535 |
ESTHER : Zhang_1998_Fold.Des_3_535 |
PubMedSearch : Zhang_1998_Fold.Des_3_535 |
PubMedID: 9889164 |
No structure scheme yet for this family
Genes Proteins in abh_upf0017 family (730)
Fragments of genes in abh_upf0017 family (50)
No fragment of genesSubstrates in abh_upf0017 family (9)
Inhibitors in abh_upf0017 family (5)