PhoPQ_related
Relationship
Comment
IPR009199 PIRSF014728 PhoPQ-activated pathogenicity-related protein, PqaA type. Proteins in this entry are believed to play a role in virulence/pathogenicity in Salmonella. Salmonella typhi PqaA has been shown to be activated by PhoP/Q two-component regulatory system, which regulates many virulence genes Baker et al 1997. It has been also shown to confer resistance to antimicrobial peptides (melittin).
Autocrine proliferation repressor protein A (AprA, CfaD) is a protein secreted by Dictyostelium discoideum cells. AprA has DPPIV-like protease activity MEROPS ClanSC family S82 Database
Interpro : IPR009199 PhoPQ-activated pathogenicity-related protein, PqaA type
PIRSF : PIRSF014728 PhoPQ-activated pathogenicity-related protein, PqaA type
Pdoc : No Pdoc
Pfam : PF10142 PhoPQ_related
Prints : No Print
EC Number : No EC Number
References (6)
| Title : Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl-peptidase IV - Herlihy_2017_Protein.Sci_26_578 |
| Author(s) : Herlihy SE , Tang Y , Phillips JE , Gomer RH |
| Ref : Protein Science , 26 :578 , 2017 |
| Abstract : Herlihy_2017_Protein.Sci_26_578 |
| ESTHER : Herlihy_2017_Protein.Sci_26_578 |
| PubMedSearch : Herlihy_2017_Protein.Sci_26_578 |
| PubMedID: 28028841 |
| Gene_locus related to this paper: dicdi-apra |
| Title : Dictyostelium cells bind a secreted autocrine factor that represses cell proliferation - Choe_2009_BMC.Biochem_10_4 |
| Author(s) : Choe JM , Bakthavatsalam D , Phillips JE , Gomer RH |
| Ref : BMC Biochem , 10 :4 , 2009 |
| Abstract : Choe_2009_BMC.Biochem_10_4 |
| ESTHER : Choe_2009_BMC.Biochem_10_4 |
| PubMedSearch : Choe_2009_BMC.Biochem_10_4 |
| PubMedID: 19187549 |
| Gene_locus related to this paper: dicdi-apra |
| Title : The secreted Dictyostelium protein CfaD is a chalone - Bakthavatsalam_2008_J.Cell.Sci_121_2473 |
| Author(s) : Bakthavatsalam D , Brock DA , Nikravan NN , Houston KD , Hatton RD , Gomer RH |
| Ref : Journal of Cell Science , 121 :2473 , 2008 |
| Abstract : Bakthavatsalam_2008_J.Cell.Sci_121_2473 |
| ESTHER : Bakthavatsalam_2008_J.Cell.Sci_121_2473 |
| PubMedSearch : Bakthavatsalam_2008_J.Cell.Sci_121_2473 |
| PubMedID: 18611962 |
| Gene_locus related to this paper: dicdi-apra |
| Title : Rcs and PhoPQ regulatory overlap in the control of Salmonella enterica virulence. - Garcia-Calderon_2007_J.Bacteriol_189_6635 |
| Author(s) : Garcia-Calderon CB , Casadesus J , Ramos-Morales F |
| Ref : Journal of Bacteriology , 189 :6635 , 2007 |
| Abstract : Garcia-Calderon_2007_J.Bacteriol_189_6635 |
| ESTHER : Garcia-Calderon_2007_J.Bacteriol_189_6635 |
| PubMedSearch : Garcia-Calderon_2007_J.Bacteriol_189_6635 |
| PubMedID: 17616593 |
| Title : A secreted factor represses cell proliferation in Dictyostelium - Brock_2005_Development_132_4553 |
| Author(s) : Brock DA , Gomer RH |
| Ref : Development , 132 :4553 , 2005 |
| Abstract : Brock_2005_Development_132_4553 |
| ESTHER : Brock_2005_Development_132_4553 |
| PubMedSearch : Brock_2005_Development_132_4553 |
| PubMedID: 16176950 |
| Gene_locus related to this paper: dicdi-apra |
| Title : PhoP\/Q regulated genes in Salmonella typhi identification of melittin sensitive mutants - Baker_1997_Microb.Pathog_22_165 |
| Author(s) : Baker SJ , Daniels C , Morona R |
| Ref : Microb Pathog , 22 :165 , 1997 |
| Abstract : Baker_1997_Microb.Pathog_22_165 |
| ESTHER : Baker_1997_Microb.Pathog_22_165 |
| PubMedSearch : Baker_1997_Microb.Pathog_22_165 |
| PubMedID: 9075219 |
No structure scheme yet for this family
Genes Proteins in PhoPQ_related family (63)
Fragments of genes in PhoPQ_related family (3)
No fragment of genesNo substrate
No Inhibitor