Interpro : IPR002018 Carboxylesterase, type B
PIRSF : PIRSF005676 COesterase
Pdoc : PDOC00112
Pfam : PF00135 COesterase
Prints : No Print
EC Number : 3.1.1.1
Title : Carboxylesterases in lipid metabolism: from mouse to human - Lian_2018_Protein.Cell_9_178 |
Author(s) : Lian J , Nelson R , Lehner R |
Ref : Protein Cell , 9 :178 , 2018 |
Abstract : Lian_2018_Protein.Cell_9_178 |
ESTHER : Lian_2018_Protein.Cell_9_178 |
PubMedSearch : Lian_2018_Protein.Cell_9_178 |
PubMedID: 28677105 |
Gene_locus related to this paper: human-CES1 |
Title : Nomenclature for alleles of the human carboxylesterase 1 gene - |
Author(s) : Rasmussen HB , Madsen MB , Hansen PR |
Ref : Pharmacogenet Genomics , 27 :78 , 2017 |
PubMedID: 27831961 |
Gene_locus related to this paper: human-CES1 |
Title : Comparison of substrate specificity among human arylacetamide deacetylase and carboxylesterases - Fukami_2015_Eur.J.Pharm.Sci_78_47 |
Author(s) : Fukami T , Kariya M , Kurokawa T , Iida A , Nakajima M |
Ref : Eur J Pharm Sci , 78 :47 , 2015 |
Abstract : Fukami_2015_Eur.J.Pharm.Sci_78_47 |
ESTHER : Fukami_2015_Eur.J.Pharm.Sci_78_47 |
PubMedSearch : Fukami_2015_Eur.J.Pharm.Sci_78_47 |
PubMedID: 26164127 |
Gene_locus related to this paper: human-AADAC , human-CES1 , human-CES2 |
Title : Carboxylesterases: structure, function and polymorphism in mammals - Satoh_2010_J.Pestic.Sci_35_218 |
Author(s) : Satoh T , Hosokawa M |
Ref : Journal of Pesticide Science , 35 :218 , 2010 |
Abstract : Satoh_2010_J.Pestic.Sci_35_218 |
ESTHER : Satoh_2010_J.Pestic.Sci_35_218 |
PubMedSearch : Satoh_2010_J.Pestic.Sci_35_218 |
PubMedID: |
Title : Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins - Holmes_2010_Mamm.Genome_21_427 |
Author(s) : Holmes RS , Wright MW , Laulederkind SJ , Cox LA , Hosokawa M , Imai T , Ishibashi S , Lehner R , Miyazaki M , Perkins EJ , Potter PM , Redinbo MR , Robert J , Satoh T , Yamashita T , Yan B , Yokoi T , Zechner R , Maltais LJ |
Ref : Mamm Genome , 21 :427 , 2010 |
Abstract : Holmes_2010_Mamm.Genome_21_427 |
ESTHER : Holmes_2010_Mamm.Genome_21_427 |
PubMedSearch : Holmes_2010_Mamm.Genome_21_427 |
PubMedID: 20931200 |
Gene_locus related to this paper: human-CES1 , human-CES2 , human-CES3 , human-CES4A , human-CES5A |
Title : Genomic analysis of the carboxylesterases: identification and classification of novel forms - Williams_2010_Mol.Phylogenet.Evol_57_23 |
Author(s) : Williams ET , Wang H , Wrighton SA , Qian YW , Perkins EJ |
Ref : Mol Phylogenet Evol , 57 :23 , 2010 |
Abstract : Williams_2010_Mol.Phylogenet.Evol_57_23 |
ESTHER : Williams_2010_Mol.Phylogenet.Evol_57_23 |
PubMedSearch : Williams_2010_Mol.Phylogenet.Evol_57_23 |
PubMedID: 20510380 |
Gene_locus related to this paper: macfa-a0a2k5uar1 |
Title : Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin - Hemmert_2010_Mol.Pharmacol_77_508 |
Author(s) : Hemmert AC , Otto TC , Wierdl M , Edwards CC , Fleming CD , MacDonald M , Cashman JR , Potter PM , Cerasoli DM , Redinbo MR |
Ref : Molecular Pharmacology , 77 :508 , 2010 |
Abstract : Hemmert_2010_Mol.Pharmacol_77_508 |
ESTHER : Hemmert_2010_Mol.Pharmacol_77_508 |
PubMedSearch : Hemmert_2010_Mol.Pharmacol_77_508 |
PubMedID: 20051531 |
Gene_locus related to this paper: human-CES1 |
Title : Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs - Hosokawa_2008_Molecules_13_412 |
Author(s) : Hosokawa M |
Ref : Molecules , 13 :412 , 2008 |
Abstract : Hosokawa_2008_Molecules_13_412 |
ESTHER : Hosokawa_2008_Molecules_13_412 |
PubMedSearch : Hosokawa_2008_Molecules_13_412 |
PubMedID: 18305428 |
Title : Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun - Fleming_2007_Biochemistry_46_5063 |
Author(s) : Fleming CD , Edwards CC , Kirby SD , Maxwell DM , Potter PM , Cerasoli DM , Redinbo MR |
Ref : Biochemistry , 46 :5063 , 2007 |
Abstract : Fleming_2007_Biochemistry_46_5063 |
ESTHER : Fleming_2007_Biochemistry_46_5063 |
PubMedSearch : Fleming_2007_Biochemistry_46_5063 |
PubMedID: 17407327 |
Gene_locus related to this paper: human-CES1 |
Title : Structure, function and regulation of carboxylesterases - Satoh_2006_Chem.Biol.Interact_162_195 |
Author(s) : Satoh T , Hosokawa M |
Ref : Chemico-Biological Interactions , 162 :195 , 2006 |
Abstract : Satoh_2006_Chem.Biol.Interact_162_195 |
ESTHER : Satoh_2006_Chem.Biol.Interact_162_195 |
PubMedSearch : Satoh_2006_Chem.Biol.Interact_162_195 |
PubMedID: 16919614 |
Title : Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1 - Bencharit_2006_J.Mol.Biol_363_201 |
Author(s) : Bencharit S , Edwards CC , Morton CL , Howard-Williams EL , Kuhn P , Potter PM , Redinbo MR |
Ref : Journal of Molecular Biology , 363 :201 , 2006 |
Abstract : Bencharit_2006_J.Mol.Biol_363_201 |
ESTHER : Bencharit_2006_J.Mol.Biol_363_201 |
PubMedSearch : Bencharit_2006_J.Mol.Biol_363_201 |
PubMedID: 16962139 |
Gene_locus related to this paper: human-CES1 |
Title : Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil - Fleming_2005_J.Mol.Biol_352_165 |
Author(s) : Fleming CD , Bencharit S , Edwards CC , Hyatt JL , Tsurkan L , Bai F , Fraga C , Morton CL , Howard-Williams EL , Potter PM , Redinbo MR |
Ref : Journal of Molecular Biology , 352 :165 , 2005 |
Abstract : Fleming_2005_J.Mol.Biol_352_165 |
ESTHER : Fleming_2005_J.Mol.Biol_352_165 |
PubMedSearch : Fleming_2005_J.Mol.Biol_352_165 |
PubMedID: 16081098 |
Gene_locus related to this paper: human-CES1 |
Title : Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition - Bencharit_2003_Chem.Biol_10_341 |
Author(s) : Bencharit S , Morton CL , Hyatt JL , Kuhn P , Danks MK , Potter PM , Redinbo MR |
Ref : Chemical Biology , 10 :341 , 2003 |
Abstract : Bencharit_2003_Chem.Biol_10_341 |
ESTHER : Bencharit_2003_Chem.Biol_10_341 |
PubMedSearch : Bencharit_2003_Chem.Biol_10_341 |
PubMedID: 12725862 |
Gene_locus related to this paper: human-CES1 |
Title : Structural insights into CPT-11 activation by mammalian carboxylesterases - Bencharit_2002_Nat.Struct.Biol_9_337 |
Author(s) : Bencharit S , Morton CL , Howard-Williams EL , Danks MK , Potter PM , Redinbo MR |
Ref : Nat Struct Biol , 9 :337 , 2002 |
Abstract : Bencharit_2002_Nat.Struct.Biol_9_337 |
ESTHER : Bencharit_2002_Nat.Struct.Biol_9_337 |
PubMedSearch : Bencharit_2002_Nat.Struct.Biol_9_337 |
PubMedID: 11967565 |
Gene_locus related to this paper: rabit-1cxes |
Title : On the origins of esterases - Myers_1988_Mol.Biol.Evol_5_113 |
Author(s) : Myers M , Richmond RC , Oakeshott JG |
Ref : Molecular Biology Evolution , 5 :113 , 1988 |
Abstract : Myers_1988_Mol.Biol.Evol_5_113 |
ESTHER : Myers_1988_Mol.Biol.Evol_5_113 |
PubMedSearch : Myers_1988_Mol.Biol.Evol_5_113 |
PubMedID: 3163407 |
Structures (22)
Genes Proteins in Carb_B_Chordata family (543)
Fragments of genes in Carb_B_Chordata family (295)
Structures in Carb_B_Chordata family (22)Substrates in Carb_B_Chordata family (144)
Inhibitors in Carb_B_Chordata family (67)