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Avian-virus_vlip

Relationship

Family: Avian-virus_vlip

Block: L

Parent Family: No family

Comment

This family has been recognized as alpha/beta hydrolase by Kamil et al. Previously associated with Lipoprotein_lipase family but is also close to phospholipase. vLIP may not serve as a traditional lipase enzyme, but the serine nucleophile position is essential in vivo for the viral functions of vLIP. Could be example of repurposing alpha/beta hydrolase fold toward a nonenzymatic role, possibly in lipid bonding

Database

Interpro : IPR000734 Lipase

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF00151 Lipase , IPR013818 Lipase

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

References (1)

Title : vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus - Kamil_2005_J.Virol_79_6984
Author(s) : Kamil JP , Tischer BK , Trapp S , Nair VK , Osterrieder N , Kung HJ
Ref : J Virol , 79 :6984 , 2005
Abstract : Kamil_2005_J.Virol_79_6984
ESTHER : Kamil_2005_J.Virol_79_6984
PubMedSearch : Kamil_2005_J.Virol_79_6984
PubMedID: 15890938
Gene_locus related to this paper: mardi-ORF1

No structure scheme yet for this family

Genes Proteins in Avian-virus_vlip family (7)

No fragment of genes

No fragment of genes

No substrate

No Inhibitor