Full name : Spalding Tracy A
First name : Tracy A
Mail : ACADIA Pharmaceuticals Inc., 3911 Sorrento Valley Blvd., San Diego, CA 92129
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Country : USA
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| Title : AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model - Bradley_2010_Neuropharmacol_58_365 |
| Author(s) : Bradley SR , Lameh J , Ohrmund L , Son T , Bajpai A , Nguyen D , Friberg M , Burstein ES , Spalding TA , Ott TR , Schiffer HH , Tabatabaei A , McFarland K , Davis RE , Bonhaus DW |
| Ref : Neuropharmacology , 58 :365 , 2010 |
| Abstract : Bradley_2010_Neuropharmacol_58_365 |
| ESTHER : Bradley_2010_Neuropharmacol_58_365 |
| PubMedSearch : Bradley_2010_Neuropharmacol_58_365 |
| PubMedID: 19835892 |
| Title : Structural requirements of transmembrane domain 3 for activation by the M1 muscarinic receptor agonists AC-42, AC-260584, clozapine, and N-desmethylclozapine: evidence for three distinct modes of receptor activation - Spalding_2006_Mol.Pharmacol_70_1974 |
| Author(s) : Spalding TA , Ma JN , Ott TR , Friberg M , Bajpai A , Bradley SR , Davis RE , Brann MR , Burstein ES |
| Ref : Molecular Pharmacology , 70 :1974 , 2006 |
| Abstract : Spalding_2006_Mol.Pharmacol_70_1974 |
| ESTHER : Spalding_2006_Mol.Pharmacol_70_1974 |
| PubMedSearch : Spalding_2006_Mol.Pharmacol_70_1974 |
| PubMedID: 16959945 |
| Title : The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine - Weiner_2004_Psychopharmacology.(Berl)_177_207 |
| Author(s) : Weiner DM , Meltzer HY , Veinbergs I , Donohue EM , Spalding TA , Smith TT , Mohell N , Harvey SC , Lameh J , Nash N , Vanover KE , Olsson R , Jayathilake K , Lee M , Levey AI , Hacksell U , Burstein ES , Davis RE , Brann MR |
| Ref : Psychopharmacology (Berl) , 177 :207 , 2004 |
| Abstract : Weiner_2004_Psychopharmacology.(Berl)_177_207 |
| ESTHER : Weiner_2004_Psychopharmacology.(Berl)_177_207 |
| PubMedSearch : Weiner_2004_Psychopharmacology.(Berl)_177_207 |
| PubMedID: 15258717 |
| Title : Constitutively active muscarinic receptors - Spalding_2001_Life.Sci_68(22-23)_2511 |
| Author(s) : Spalding TA , Burstein ES |
| Ref : Life Sciences , 68 :2511 , 2001 |
| Abstract : Spalding_2001_Life.Sci_68(22-23)_2511 |
| ESTHER : Spalding_2001_Life.Sci_68(22-23)_2511 |
| PubMedSearch : Spalding_2001_Life.Sci_68(22-23)_2511 |
| PubMedID: 11392620 |
| Title : Exploring the potential for subtype-selective muscarinic agonists in glaucoma - Gil_2001_Life.Sci_68(22-23)_2601 |
| Author(s) : Gil DW , Spalding TA , Kharlamb A , Skjaerbaek N , Uldam A , Trotter C , Li D , WoldeMussie E , Wheeler L , Brann M |
| Ref : Life Sciences , 68 :2601 , 2001 |
| Abstract : Gil_2001_Life.Sci_68(22-23)_2601 |
| ESTHER : Gil_2001_Life.Sci_68(22-23)_2601 |
| PubMedSearch : Gil_2001_Life.Sci_68(22-23)_2601 |
| PubMedID: 11392632 |
| Title : Constitutive activation of the m5 muscarinic receptor by a series of mutations at the extracellular end of transmembrane 6 - Spalding_1997_Biochemistry_36_10109 |
| Author(s) : Spalding TA , Burstein ES , Wells JW , Brann MR |
| Ref : Biochemistry , 36 :10109 , 1997 |
| Abstract : Spalding_1997_Biochemistry_36_10109 |
| ESTHER : Spalding_1997_Biochemistry_36_10109 |
| PubMedSearch : Spalding_1997_Biochemistry_36_10109 |
| PubMedID: 9254607 |
| Title : Interactions of muscarinic receptors with the heterotrimeric G proteins Gq and G12: transduction of proliferative signals - Burstein_1997_J.Neurochem_68_525 |
| Author(s) : Burstein ES , Brauner-Osborne H , Spalding TA , Conklin BR , Brann MR |
| Ref : Journal of Neurochemistry , 68 :525 , 1997 |
| Abstract : Burstein_1997_J.Neurochem_68_525 |
| ESTHER : Burstein_1997_J.Neurochem_68_525 |
| PubMedSearch : Burstein_1997_J.Neurochem_68_525 |
| PubMedID: 9003037 |
| Title : Poster: Structure\/function of muscarinic receptor coupling to G proteins: random-saturation mutagenesis identifies a critical determinant of receptor affinity for G proteins - |
| Author(s) : Burstein ES , Spalding TA , Jorgensen HB , Hill-Eubanks D , Brann MR |
| Ref : Life Sciences , 56(11-12) :1029 , 1995 |
| PubMedID: |
| Title : Poster: Pharmacology of a constitutively activated m5 muscarinic receptor - |
| Author(s) : Spalding TA , Burstein ES , Jorgensen HB , Hill-Eubanks D , Brann MR |
| Ref : Life Sciences , 56(11-12) :1021 , 1995 |
| PubMedID: |
| Title : Acetylcholine mustard labels the binding site aspartate in muscarinic acetylcholine receptors - Spalding_1994_J.Biol.Chem_269_4092 |
| Author(s) : Spalding TA , Birdsall NJ , Curtis CA , Hulme EC |
| Ref : Journal of Biological Chemistry , 269 :4092 , 1994 |
| Abstract : Spalding_1994_J.Biol.Chem_269_4092 |
| ESTHER : Spalding_1994_J.Biol.Chem_269_4092 |
| PubMedSearch : Spalding_1994_J.Biol.Chem_269_4092 |
| PubMedID: 8307968 |
| Title : Poster: Studies on muscarinic receptors using nitrogen mustards - |
| Author(s) : Birdsall NJ , Spalding TA , Corrie JE , Curtis CA , Hulme EC |
| Ref : Life Sciences , 52(5-6) :561 , 1993 |
| PubMedID: |
| Title : Studies of the pharmacology, localization, and structure of muscarinic acetylcholine receptors - |
| Author(s) : Brann MR , Jorgensen HB , Burstein ES , Spalding TA , Ellis J , Jones SV , Hill-Eubanks D |
| Ref : Annals of the New York Academy of Sciences , 707 :225 , 1993 |
| PubMedID: 9137555 |
| Title : Blockade of muscarinic receptors by alkylating agonist analogues - |
| Author(s) : Hulme EC , Spalding TA , Curtis CA , Birdsall NJ , Corrie JE |
| Ref : Biochemical Society Transactions , 18 :440 , 1990 |
| PubMedID: 2373233 |