Full name : Sine Steven M
First name : Steven M
Mail : Mayo Clinic 200, 1st Street SW - Rm. 1-135 MSB, Rochester, MN 55905
Zip Code :
City :
Country : USA
Email : sine@mayo.edu
Phone : 15072849404
Fax : 15072849420
Website :
Directory :
| Title : Nicotinic receptor transduction zone: invariant arginine couples to multiple electron-rich residues - Mukhtasimova_2013_Biophys.J_104_355 |
| Author(s) : Mukhtasimova N , Sine SM |
| Ref : Biophysical Journal , 104 :355 , 2013 |
| Abstract : Mukhtasimova_2013_Biophys.J_104_355 |
| ESTHER : Mukhtasimova_2013_Biophys.J_104_355 |
| PubMedSearch : Mukhtasimova_2013_Biophys.J_104_355 |
| PubMedID: 23442857 |
| Title : Inter-residue coupling contributes to high-affinity subtype-selective binding of alpha-bungarotoxin to nicotinic receptors - Sine_2013_Biochem.J_454_311 |
| Author(s) : Sine SM , Huang S , Li SX , daCosta CJ , Chen L |
| Ref : Biochemical Journal , 454 :311 , 2013 |
| Abstract : Sine_2013_Biochem.J_454_311 |
| ESTHER : Sine_2013_Biochem.J_454_311 |
| PubMedSearch : Sine_2013_Biochem.J_454_311 |
| PubMedID: 23802200 |
| Title : Stoichiometry for drug potentiation of a pentameric ion channel - daCosta_2013_Proc.Natl.Acad.Sci.U.S.A_110_6595 |
| Author(s) : daCosta CJ , Sine SM |
| Ref : Proc Natl Acad Sci U S A , 110 :6595 , 2013 |
| Abstract : daCosta_2013_Proc.Natl.Acad.Sci.U.S.A_110_6595 |
| ESTHER : daCosta_2013_Proc.Natl.Acad.Sci.U.S.A_110_6595 |
| PubMedSearch : daCosta_2013_Proc.Natl.Acad.Sci.U.S.A_110_6595 |
| PubMedID: 23576748 |
| Title : Stoichiometry for activation of neuronal alpha7 nicotinic receptors - Andersen_2013_Proc.Natl.Acad.Sci.U.S.A_110_20819 |
| Author(s) : Andersen N , Corradi J , Sine SM , Bouzat C |
| Ref : Proc Natl Acad Sci U S A , 110 :20819 , 2013 |
| Abstract : Andersen_2013_Proc.Natl.Acad.Sci.U.S.A_110_20819 |
| ESTHER : Andersen_2013_Proc.Natl.Acad.Sci.U.S.A_110_20819 |
| PubMedSearch : Andersen_2013_Proc.Natl.Acad.Sci.U.S.A_110_20819 |
| PubMedID: 24297903 |
| Title : Complex between alpha-bungarotoxin and an alpha7 nicotinic receptor ligand-binding domain chimaera - Huang_2013_Biochem.J_454_303 |
| Author(s) : Huang S , Li SX , Bren N , Cheng K , Gomoto R , Chen L , Sine SM |
| Ref : Biochemical Journal , 454 :303 , 2013 |
| Abstract : Huang_2013_Biochem.J_454_303 |
| ESTHER : Huang_2013_Biochem.J_454_303 |
| PubMedSearch : Huang_2013_Biochem.J_454_303 |
| PubMedID: 23800261 |
| Title : Highly fatal fast-channel syndrome caused by AChR epsilon subunit mutation at the agonist binding site - Shen_2012_Neurology_79_449 |
| Author(s) : Shen XM , Brengman JM , Edvardson S , Sine SM , Engel AG |
| Ref : Neurology , 79 :449 , 2012 |
| Abstract : Shen_2012_Neurology_79_449 |
| ESTHER : Shen_2012_Neurology_79_449 |
| PubMedSearch : Shen_2012_Neurology_79_449 |
| PubMedID: 22592360 |
| Title : Myasthenic syndrome AChRalpha C-loop mutant disrupts initiation of channel gating - Shen_2012_J.Clin.Invest_122_2613 |
| Author(s) : Shen XM , Brengman JM , Sine SM , Engel AG |
| Ref : J Clinical Investigation , 122 :2613 , 2012 |
| Abstract : Shen_2012_J.Clin.Invest_122_2613 |
| ESTHER : Shen_2012_J.Clin.Invest_122_2613 |
| PubMedSearch : Shen_2012_J.Clin.Invest_122_2613 |
| PubMedID: 22728938 |
| Title : End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease - Sine_2012_Physiol.Rev_92_1189 |
| Author(s) : Sine SM |
| Ref : Physiol Rev , 92 :1189 , 2012 |
| Abstract : Sine_2012_Physiol.Rev_92_1189 |
| ESTHER : Sine_2012_Physiol.Rev_92_1189 |
| PubMedSearch : Sine_2012_Physiol.Rev_92_1189 |
| PubMedID: 22811427 |
| Title : Intramembrane proton binding site linked to activation of bacterial pentameric ion channel - Wang_2012_J.Biol.Chem_287_6482 |
| Author(s) : Wang HL , Cheng X , Sine SM |
| Ref : Journal of Biological Chemistry , 287 :6482 , 2012 |
| Abstract : Wang_2012_J.Biol.Chem_287_6482 |
| ESTHER : Wang_2012_J.Biol.Chem_287_6482 |
| PubMedSearch : Wang_2012_J.Biol.Chem_287_6482 |
| PubMedID: 22084238 |
| Title : Functional relationships between agonist binding sites and coupling regions of homomeric Cys-loop receptors - Andersen_2011_J.Neurosci_31_3662 |
| Author(s) : Andersen N , Corradi J , Bartos M , Sine SM , Bouzat C |
| Ref : Journal of Neuroscience , 31 :3662 , 2011 |
| Abstract : Andersen_2011_J.Neurosci_31_3662 |
| ESTHER : Andersen_2011_J.Neurosci_31_3662 |
| PubMedSearch : Andersen_2011_J.Neurosci_31_3662 |
| PubMedID: 21389221 |
| Title : Ligand-binding domain of an alpha7-nicotinic receptor chimera and its complex with agonist - Li_2011_Nat.Neurosci_14_1253 |
| Author(s) : Li SX , Huang S , Bren N , Noridomi K , Dellisanti CD , Sine SM , Chen L |
| Ref : Nat Neurosci , 14 :1253 , 2011 |
| Abstract : Li_2011_Nat.Neurosci_14_1253 |
| ESTHER : Li_2011_Nat.Neurosci_14_1253 |
| PubMedSearch : Li_2011_Nat.Neurosci_14_1253 |
| PubMedID: 21909087 |
| Title : Single-channel and structural foundations of neuronal alpha7 acetylcholine receptor potentiation - daCosta_2011_J.Neurosci_31_13870 |
| Author(s) : daCosta CJ , Free CR , Corradi J , Bouzat C , Sine SM |
| Ref : Journal of Neuroscience , 31 :13870 , 2011 |
| Abstract : daCosta_2011_J.Neurosci_31_13870 |
| ESTHER : daCosta_2011_J.Neurosci_31_13870 |
| PubMedSearch : daCosta_2011_J.Neurosci_31_13870 |
| PubMedID: 21957249 |
| Title : On the origin of ion selectivity in the Cys-loop receptor family - Sine_2010_J.Mol.Neurosci_40_70 |
| Author(s) : Sine SM , Wang HL , Hansen S , Taylor P |
| Ref : Journal of Molecular Neuroscience , 40 :70 , 2010 |
| Abstract : Sine_2010_J.Mol.Neurosci_40_70 |
| ESTHER : Sine_2010_J.Mol.Neurosci_40_70 |
| PubMedSearch : Sine_2010_J.Mol.Neurosci_40_70 |
| PubMedID: 19728176 |
| Title : What have we learned from the congenital myasthenic syndromes - Engel_2010_J.Mol.Neurosci_40_143 |
| Author(s) : Engel AG , Shen XM , Selcen D , Sine SM |
| Ref : Journal of Molecular Neuroscience , 40 :143 , 2010 |
| Abstract : Engel_2010_J.Mol.Neurosci_40_143 |
| ESTHER : Engel_2010_J.Mol.Neurosci_40_143 |
| PubMedSearch : Engel_2010_J.Mol.Neurosci_40_143 |
| PubMedID: 19688192 |
| Title : Number and locations of agonist binding sites required to activate homomeric Cys-loop receptors - Rayes_2009_J.Neurosci_29_6022 |
| Author(s) : Rayes D , De Rosa MJ , Sine SM , Bouzat C |
| Ref : Journal of Neuroscience , 29 :6022 , 2009 |
| Abstract : Rayes_2009_J.Neurosci_29_6022 |
| ESTHER : Rayes_2009_J.Neurosci_29_6022 |
| PubMedSearch : Rayes_2009_J.Neurosci_29_6022 |
| PubMedID: 19420269 |
| Title : Detection and trapping of intermediate states priming nicotinic receptor channel opening - Mukhtasimova_2009_Nature_459_451 |
| Author(s) : Mukhtasimova N , Lee WY , Wang HL , Sine SM |
| Ref : Nature , 459 :451 , 2009 |
| Abstract : Mukhtasimova_2009_Nature_459_451 |
| ESTHER : Mukhtasimova_2009_Nature_459_451 |
| PubMedSearch : Mukhtasimova_2009_Nature_459_451 |
| PubMedID: 19339970 |
| Title : Binding to gating transduction in nicotinic receptors: Cys-loop energetically couples to pre-M1 and M2-M3 regions - Lee_2009_J.Neurosci_29_3189 |
| Author(s) : Lee WY , Free CR , Sine SM |
| Ref : Journal of Neuroscience , 29 :3189 , 2009 |
| Abstract : Lee_2009_J.Neurosci_29_3189 |
| ESTHER : Lee_2009_J.Neurosci_29_3189 |
| PubMedSearch : Lee_2009_J.Neurosci_29_3189 |
| PubMedID: 19279256 |
| Title : Molecular-dynamics simulations of ELIC-a prokaryotic homologue of the nicotinic acetylcholine receptor - Cheng_2009_Biophys.J_96_4502 |
| Author(s) : Cheng X , Ivanov I , Wang H , Sine SM , McCammon JA |
| Ref : Biophysical Journal , 96 :4502 , 2009 |
| Abstract : Cheng_2009_Biophys.J_96_4502 |
| ESTHER : Cheng_2009_Biophys.J_96_4502 |
| PubMedSearch : Cheng_2009_Biophys.J_96_4502 |
| PubMedID: 19486673 |
| Title : Single-channel current through nicotinic receptor produced by closure of binding site C-loop - Wang_2009_Biophys.J_96_3582 |
| Author(s) : Wang HL , Toghraee R , Papke D , Cheng XL , McCammon JA , Ravaioli U , Sine SM |
| Ref : Biophysical Journal , 96 :3582 , 2009 |
| Abstract : Wang_2009_Biophys.J_96_3582 |
| ESTHER : Wang_2009_Biophys.J_96_3582 |
| PubMedSearch : Wang_2009_Biophys.J_96_3582 |
| PubMedID: 19413963 |
| Title : Further observations in congenital myasthenic syndromes - Engel_2008_Ann.N.Y.Acad.Sci_1132_104 |
| Author(s) : Engel AG , Shen XM , Selcen D , Sine SM |
| Ref : Annals of the New York Academy of Sciences , 1132 :104 , 2008 |
| Abstract : Engel_2008_Ann.N.Y.Acad.Sci_1132_104 |
| ESTHER : Engel_2008_Ann.N.Y.Acad.Sci_1132_104 |
| PubMedSearch : Engel_2008_Ann.N.Y.Acad.Sci_1132_104 |
| PubMedID: 18567859 |
| Title : Nicotinic receptor interloop proline anchors beta1-beta2 and Cys loops in coupling agonist binding to channel gating - Lee_2008_J.Gen.Physiol_132_265 |
| Author(s) : Lee WY , Free CR , Sine SM |
| Ref : Journal of General Physiology , 132 :265 , 2008 |
| Abstract : Lee_2008_J.Gen.Physiol_132_265 |
| ESTHER : Lee_2008_J.Gen.Physiol_132_265 |
| PubMedSearch : Lee_2008_J.Gen.Physiol_132_265 |
| PubMedID: 18663134 |
| Title : An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance - Hansen_2008_J.Biol.Chem_283_36066 |
| Author(s) : Hansen SB , Wang HL , Taylor P , Sine SM |
| Ref : Journal of Biological Chemistry , 283 :36066 , 2008 |
| Abstract : Hansen_2008_J.Biol.Chem_283_36066 |
| ESTHER : Hansen_2008_J.Biol.Chem_283_36066 |
| PubMedSearch : Hansen_2008_J.Biol.Chem_283_36066 |
| PubMedID: 18940802 |
| Title : Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating - Shen_2008_J.Clin.Invest_118_1867 |
| Author(s) : Shen XM , Fukuda T , Ohno K , Sine SM , Engel AG |
| Ref : J Clinical Investigation , 118 :1867 , 2008 |
| Abstract : Shen_2008_J.Clin.Invest_118_1867 |
| ESTHER : Shen_2008_J.Clin.Invest_118_1867 |
| PubMedSearch : Shen_2008_J.Clin.Invest_118_1867 |
| PubMedID: 18398509 |
| Title : Recent structural and mechanistic insights into endplate acetylcholine receptors - Sine_2008_Ann.N.Y.Acad.Sci_1132_53 |
| Author(s) : Sine SM , Gao F , Lee WY , Mukhtasimova N , Wang HL , Engel AG |
| Ref : Annals of the New York Academy of Sciences , 1132 :53 , 2008 |
| Abstract : Sine_2008_Ann.N.Y.Acad.Sci_1132_53 |
| ESTHER : Sine_2008_Ann.N.Y.Acad.Sci_1132_53 |
| PubMedSearch : Sine_2008_Ann.N.Y.Acad.Sci_1132_53 |
| PubMedID: 18567853 |
| Title : Control of cation permeation through the nicotinic receptor channel - Wang_2008_PLoS.Comput.Biol_4_e41 |
| Author(s) : Wang HL , Cheng X , Taylor P , McCammon JA , Sine SM |
| Ref : PLoS Comput Biol , 4 :e41 , 2008 |
| Abstract : Wang_2008_PLoS.Comput.Biol_4_e41 |
| ESTHER : Wang_2008_PLoS.Comput.Biol_4_e41 |
| PubMedSearch : Wang_2008_PLoS.Comput.Biol_4_e41 |
| PubMedID: 18282090 |
| Title : Morantel allosterically enhances channel gating of neuronal nicotinic acetylcholine alpha 3 beta 2 receptors - Wu_2008_Mol.Pharmacol_74_466 |
| Author(s) : Wu TY , Smith CM , Sine SM , Levandoski MM |
| Ref : Molecular Pharmacology , 74 :466 , 2008 |
| Abstract : Wu_2008_Mol.Pharmacol_74_466 |
| ESTHER : Wu_2008_Mol.Pharmacol_74_466 |
| PubMedSearch : Wu_2008_Mol.Pharmacol_74_466 |
| PubMedID: 18458055 |
| Title : The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization - Bouzat_2008_J.Neurosci_28_7808 |
| Author(s) : Bouzat C , Bartos M , Corradi J , Sine SM |
| Ref : Journal of Neuroscience , 28 :7808 , 2008 |
| Abstract : Bouzat_2008_J.Neurosci_28_7808 |
| ESTHER : Bouzat_2008_J.Neurosci_28_7808 |
| PubMedSearch : Bouzat_2008_J.Neurosci_28_7808 |
| PubMedID: 18667613 |
| Title : An intersubunit trigger of channel gating in the muscle nicotinic receptor - Mukhtasimova_2007_J.Neurosci_27_4110 |
| Author(s) : Mukhtasimova N , Sine SM |
| Ref : Journal of Neuroscience , 27 :4110 , 2007 |
| Abstract : Mukhtasimova_2007_J.Neurosci_27_4110 |
| ESTHER : Mukhtasimova_2007_J.Neurosci_27_4110 |
| PubMedSearch : Mukhtasimova_2007_J.Neurosci_27_4110 |
| PubMedID: 17428989 |
| Title : Nanosecond-timescale conformational dynamics of the human alpha7 nicotinic acetylcholine receptor - Cheng_2007_Biophys.J_93_2622 |
| Author(s) : Cheng X , Ivanov I , Wang H , Sine SM , McCammon JA |
| Ref : Biophysical Journal , 93 :2622 , 2007 |
| Abstract : Cheng_2007_Biophys.J_93_2622 |
| ESTHER : Cheng_2007_Biophys.J_93_2622 |
| PubMedSearch : Cheng_2007_Biophys.J_93_2622 |
| PubMedID: 17573436 |
| Title : Barriers to ion translocation in cationic and anionic receptors from the Cys-loop family - Ivanov_2007_J.Am.Chem.Soc_129_8217 |
| Author(s) : Ivanov I , Cheng X , Sine SM , McCammon JA |
| Ref : J Am Chem Soc , 129 :8217 , 2007 |
| Abstract : Ivanov_2007_J.Am.Chem.Soc_129_8217 |
| ESTHER : Ivanov_2007_J.Am.Chem.Soc_129_8217 |
| PubMedSearch : Ivanov_2007_J.Am.Chem.Soc_129_8217 |
| PubMedID: 17552523 |
| Title : Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors - Cheng_2006_PLoS.Comput.Biol_2_e134 |
| Author(s) : Cheng X , Wang H , Grant B , Sine SM , McCammon JA |
| Ref : PLoS Comput Biol , 2 :e134 , 2006 |
| Abstract : Cheng_2006_PLoS.Comput.Biol_2_e134 |
| ESTHER : Cheng_2006_PLoS.Comput.Biol_2_e134 |
| PubMedSearch : Cheng_2006_PLoS.Comput.Biol_2_e134 |
| PubMedID: 17009865 |
| Title : Slow-channel mutation in acetylcholine receptor alphaM4 domain and its efficient knockdown - Shen_2006_Ann.Neurol_60_128 |
| Author(s) : Shen XM , Deymeer F , Sine SM , Engel AG |
| Ref : Annals of Neurology , 60 :128 , 2006 |
| Abstract : Shen_2006_Ann.Neurol_60_128 |
| ESTHER : Shen_2006_Ann.Neurol_60_128 |
| PubMedSearch : Shen_2006_Ann.Neurol_60_128 |
| PubMedID: 16685696 |
| Title : Recent advances in Cys-loop receptor structure and function - Sine_2006_Nature_440_448 |
| Author(s) : Sine SM , Engel AG |
| Ref : Nature , 440 :448 , 2006 |
| Abstract : Sine_2006_Nature_440_448 |
| ESTHER : Sine_2006_Nature_440_448 |
| PubMedSearch : Sine_2006_Nature_440_448 |
| PubMedID: 16554804 |
| Title : Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop - Gao_2006_Mol.Pharmacol_70_1230 |
| Author(s) : Gao F , Mer G , Tonelli M , Hansen SB , Burghardt TP , Taylor P , Sine SM |
| Ref : Molecular Pharmacology , 70 :1230 , 2006 |
| Abstract : Gao_2006_Mol.Pharmacol_70_1230 |
| ESTHER : Gao_2006_Mol.Pharmacol_70_1230 |
| PubMedSearch : Gao_2006_Mol.Pharmacol_70_1230 |
| PubMedID: 16847142 |
| Title : Single-channel kinetic analysis of chimeric alpha7-5HT3A receptors - Rayes_2005_Mol.Pharmacol_68_1475 |
| Author(s) : Rayes D , Spitzmaul G , Sine SM , Bouzat C |
| Ref : Molecular Pharmacology , 68 :1475 , 2005 |
| Abstract : Rayes_2005_Mol.Pharmacol_68_1475 |
| ESTHER : Rayes_2005_Mol.Pharmacol_68_1475 |
| PubMedSearch : Rayes_2005_Mol.Pharmacol_68_1475 |
| PubMedID: 16118362 |
| Title : Initial coupling of binding to gating mediated by conserved residues in the muscle nicotinic receptor - Mukhtasimova_2005_J.Gen.Physiol_126_23 |
| Author(s) : Mukhtasimova N , Free C , Sine SM |
| Ref : Journal of General Physiology , 126 :23 , 2005 |
| Abstract : Mukhtasimova_2005_J.Gen.Physiol_126_23 |
| ESTHER : Mukhtasimova_2005_J.Gen.Physiol_126_23 |
| PubMedSearch : Mukhtasimova_2005_J.Gen.Physiol_126_23 |
| PubMedID: 15955875 |
| Title : Current understanding of congenital myasthenic syndromes - Engel_2005_Curr.Opin.Pharmacol_5_308 |
| Author(s) : Engel AG , Sine SM |
| Ref : Curr Opin Pharmacol , 5 :308 , 2005 |
| Abstract : Engel_2005_Curr.Opin.Pharmacol_5_308 |
| ESTHER : Engel_2005_Curr.Opin.Pharmacol_5_308 |
| PubMedSearch : Engel_2005_Curr.Opin.Pharmacol_5_308 |
| PubMedID: 15907919 |
| Title : Principal pathway coupling agonist binding to channel gating in nicotinic receptors - Lee_2005_Nature_438_243 |
| Author(s) : Lee WY , Sine SM |
| Ref : Nature , 438 :243 , 2005 |
| Abstract : Lee_2005_Nature_438_243 |
| ESTHER : Lee_2005_Nature_438_243 |
| PubMedSearch : Lee_2005_Nature_438_243 |
| PubMedID: 16281039 |
| Title : Subunit-specific contribution to agonist binding and channel gating revealed by inherited mutation in muscle acetylcholine receptor M3-M4 linker - Shen_2005_Brain_128_345 |
| Author(s) : Shen XM , Ohno K , Sine SM , Engel AG |
| Ref : Brain , 128 :345 , 2005 |
| Abstract : Shen_2005_Brain_128_345 |
| ESTHER : Shen_2005_Brain_128_345 |
| PubMedSearch : Shen_2005_Brain_128_345 |
| PubMedID: 15615813 |
| Title : Ligand-induced conformational change in the alpha7 nicotinic receptor ligand binding domain - Henchman_2005_Biophys.J_88_2564 |
| Author(s) : Henchman RH , Wang HL , Sine SM , Taylor P , McCammon JA |
| Ref : Biophysical Journal , 88 :2564 , 2005 |
| Abstract : Henchman_2005_Biophys.J_88_2564 |
| ESTHER : Henchman_2005_Biophys.J_88_2564 |
| PubMedSearch : Henchman_2005_Biophys.J_88_2564 |
| PubMedID: 15665135 |
| Title : Structural basis for epibatidine selectivity at desensitized nicotinic receptors - Pennington_2005_Mol.Pharmacol_67_123 |
| Author(s) : Pennington RA , Gao F , Sine SM , Prince RJ |
| Ref : Molecular Pharmacology , 67 :123 , 2005 |
| Abstract : Pennington_2005_Mol.Pharmacol_67_123 |
| ESTHER : Pennington_2005_Mol.Pharmacol_67_123 |
| PubMedSearch : Pennington_2005_Mol.Pharmacol_67_123 |
| PubMedID: 15496507 |
| Title : Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence - Gao_2005_J.Biol.Chem_280_8443 |
| Author(s) : Gao F , Bren N , Burghardt TP , Hansen S , Henchman RH , Taylor P , McCammon JA , Sine SM |
| Ref : Journal of Biological Chemistry , 280 :8443 , 2005 |
| Abstract : Gao_2005_J.Biol.Chem_280_8443 |
| ESTHER : Gao_2005_J.Biol.Chem_280_8443 |
| PubMedSearch : Gao_2005_J.Biol.Chem_280_8443 |
| PubMedID: 15591050 |
| Title : Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes - Ellison_2004_Biochemistry_43_16019 |
| Author(s) : Ellison M , Gao F , Wang HL , Sine SM , McIntosh JM , Olivera BM |
| Ref : Biochemistry , 43 :16019 , 2004 |
| Abstract : Ellison_2004_Biochemistry_43_16019 |
| ESTHER : Ellison_2004_Biochemistry_43_16019 |
| PubMedSearch : Ellison_2004_Biochemistry_43_16019 |
| PubMedID: 15609996 |
| Title : Invariant aspartic Acid in muscle nicotinic receptor contributes selectively to the kinetics of agonist binding - Lee_2004_J.Gen.Physiol_124_555 |
| Author(s) : Lee WY , Sine SM |
| Ref : Journal of General Physiology , 124 :555 , 2004 |
| Abstract : Lee_2004_J.Gen.Physiol_124_555 |
| ESTHER : Lee_2004_J.Gen.Physiol_124_555 |
| PubMedSearch : Lee_2004_J.Gen.Physiol_124_555 |
| PubMedID: 15504901 |
| Title : Toward atomic-scale understanding of ligand recognition in the muscle nicotinic receptor - Sine_2004_Curr.Med.Chem_11_559 |
| Author(s) : Sine SM , Wang HL , Gao F |
| Ref : Curr Med Chem , 11 :559 , 2004 |
| Abstract : Sine_2004_Curr.Med.Chem_11_559 |
| ESTHER : Sine_2004_Curr.Med.Chem_11_559 |
| PubMedSearch : Sine_2004_Curr.Med.Chem_11_559 |
| PubMedID: 15032604 |
| Title : Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel - Bouzat_2004_Nature_430_896 |
| Author(s) : Bouzat C , Gumilar F , Spitzmaul G , Wang HL , Rayes D , Hansen SB , Taylor P , Sine SM |
| Ref : Nature , 430 :896 , 2004 |
| Abstract : Bouzat_2004_Nature_430_896 |
| ESTHER : Bouzat_2004_Nature_430_896 |
| PubMedSearch : Bouzat_2004_Nature_430_896 |
| PubMedID: 15318223 |
| Title : Congenital myasthenic syndromes: multiple molecular targets at the neuromuscular junction - Engel_2003_Ann.N.Y.Acad.Sci_998_138 |
| Author(s) : Engel AG , Ohno K , Shen XM , Sine SM |
| Ref : Annals of the New York Academy of Sciences , 998 :138 , 2003 |
| Abstract : Engel_2003_Ann.N.Y.Acad.Sci_998_138 |
| ESTHER : Engel_2003_Ann.N.Y.Acad.Sci_998_138 |
| PubMedSearch : Engel_2003_Ann.N.Y.Acad.Sci_998_138 |
| PubMedID: 14592871 |
| Title : Congenital myasthenic syndromes: A diverse array of molecular targets - Engel_2003_J.Neurocytol_32_1017 |
| Author(s) : Engel AG , Ohno K , Sine SM |
| Ref : Journal of Neurocytology , 32 :1017 , 2003 |
| Abstract : Engel_2003_J.Neurocytol_32_1017 |
| ESTHER : Engel_2003_J.Neurocytol_32_1017 |
| PubMedSearch : Engel_2003_J.Neurocytol_32_1017 |
| PubMedID: 15034283 |
| Title : Congenital myasthenic syndromes: progress over the past decade - Engel_2003_Muscle.Nerve_27_4 |
| Author(s) : Engel AG , Ohno K , Sine SM |
| Ref : Muscle & Nerve , 27 :4 , 2003 |
| Abstract : Engel_2003_Muscle.Nerve_27_4 |
| ESTHER : Engel_2003_Muscle.Nerve_27_4 |
| PubMedSearch : Engel_2003_Muscle.Nerve_27_4 |
| PubMedID: 12508290 |
| Title : Mutation causing severe myasthenia reveals functional asymmetry of AChR signature cystine loops in agonist binding and gating - Shen_2003_J.Clin.Invest_111_497 |
| Author(s) : Shen XM , Ohno K , Tsujino A , Brengman JM , Gingold M , Sine SM , Engel AG |
| Ref : J Clinical Investigation , 111 :497 , 2003 |
| Abstract : Shen_2003_J.Clin.Invest_111_497 |
| ESTHER : Shen_2003_J.Clin.Invest_111_497 |
| PubMedSearch : Shen_2003_J.Clin.Invest_111_497 |
| PubMedID: 12588888 |
| Title : Asymmetric structural motions of the homomeric alpha7 nicotinic receptor ligand binding domain revealed by molecular dynamics simulation - Henchman_2003_Biophys.J_85_3007 |
| Author(s) : Henchman RH , Wang HL , Sine SM , Taylor P , McCammon JA |
| Ref : Biophysical Journal , 85 :3007 , 2003 |
| Abstract : Henchman_2003_Biophys.J_85_3007 |
| ESTHER : Henchman_2003_Biophys.J_85_3007 |
| PubMedSearch : Henchman_2003_Biophys.J_85_3007 |
| PubMedID: 14581202 |
| Title : Curariform antagonists bind in different orientations to the nicotinic receptor ligand binding domain - Wang_2003_J.Biol.Chem_278_32284 |
| Author(s) : Wang HL , Gao F , Bren N , Sine SM |
| Ref : Journal of Biological Chemistry , 278 :32284 , 2003 |
| Abstract : Wang_2003_J.Biol.Chem_278_32284 |
| ESTHER : Wang_2003_J.Biol.Chem_278_32284 |
| PubMedSearch : Wang_2003_J.Biol.Chem_278_32284 |
| PubMedID: 12799358 |
| Title : Mechanistic diversity underlying fast channel congenital myasthenic syndromes - Sine_2003_Ann.N.Y.Acad.Sci_998_128 |
| Author(s) : Sine SM , Wang HL , Ohno K , Shen XM , Lee WY , Engel AG |
| Ref : Annals of the New York Academy of Sciences , 998 :128 , 2003 |
| Abstract : Sine_2003_Ann.N.Y.Acad.Sci_998_128 |
| ESTHER : Sine_2003_Ann.N.Y.Acad.Sci_998_128 |
| PubMedSearch : Sine_2003_Ann.N.Y.Acad.Sci_998_128 |
| PubMedID: 14592870 |
| Title : Curariform antagonists bind in different orientations to acetylcholine-binding protein - Gao_2003_J.Biol.Chem_278_23020 |
| Author(s) : Gao F , Bern N , Little A , Wang HL , Hansen SB , Talley TT , Taylor P , Sine SM |
| Ref : Journal of Biological Chemistry , 278 :23020 , 2003 |
| Abstract : Gao_2003_J.Biol.Chem_278_23020 |
| ESTHER : Gao_2003_J.Biol.Chem_278_23020 |
| PubMedSearch : Gao_2003_J.Biol.Chem_278_23020 |
| PubMedID: 12682067 |
| Title : Identification of residues at the alpha and epsilon subunit interfaces mediating species selectivity of Waglerin-1 for nicotinic acetylcholine receptors - Molles_2002_J.Biol.Chem_277_5433 |
| Author(s) : Molles BE , Rezai P , Kline EF , McArdle JJ , Sine SM , Taylor P |
| Ref : Journal of Biological Chemistry , 277 :5433 , 2002 |
| Abstract : Molles_2002_J.Biol.Chem_277_5433 |
| ESTHER : Molles_2002_J.Biol.Chem_277_5433 |
| PubMedSearch : Molles_2002_J.Biol.Chem_277_5433 |
| PubMedID: 11724791 |
| Title : Residues in the epsilon subunit of the nicotinic acetylcholine receptor interact to confer selectivity of waglerin-1 for the alpha-epsilon subunit interface site - Molles_2002_Biochemistry_41_7895 |
| Author(s) : Molles BE , Tsigelny I , Nguyen PD , Gao SX , Sine SM , Taylor P |
| Ref : Biochemistry , 41 :7895 , 2002 |
| Abstract : Molles_2002_Biochemistry_41_7895 |
| ESTHER : Molles_2002_Biochemistry_41_7895 |
| PubMedSearch : Molles_2002_Biochemistry_41_7895 |
| PubMedID: 12069578 |
| Title : The nicotinic receptor ligand binding domain - Sine_2002_J.Neurobiol_53_431 |
| Author(s) : Sine SM |
| Ref : Journal of Neurobiology , 53 :431 , 2002 |
| Abstract : Sine_2002_J.Neurobiol_53_431 |
| ESTHER : Sine_2002_J.Neurobiol_53_431 |
| PubMedSearch : Sine_2002_J.Neurobiol_53_431 |
| PubMedID: 12436411 |
| Title : Naturally occurring mutations at the acetylcholine receptor binding site independently alter ACh binding and channel gating - Sine_2002_J.Gen.Physiol_120_483 |
| Author(s) : Sine SM , Shen XM , Wang HL , Ohno K , Lee WY , Tsujino A , Brengmann J , Bren N , Vajsar J , Engel AG |
| Ref : Journal of General Physiology , 120 :483 , 2002 |
| Abstract : Sine_2002_J.Gen.Physiol_120_483 |
| ESTHER : Sine_2002_J.Gen.Physiol_120_483 |
| PubMedSearch : Sine_2002_J.Gen.Physiol_120_483 |
| PubMedID: 12356851 |
| Title : Mechanism of tacrine block at adult human muscle nicotinic acetylcholine receptors - Prince_2002_J.Gen.Physiol_120_369 |
| Author(s) : Prince RJ , Pennington RA , Sine SM |
| Ref : Journal of General Physiology , 120 :369 , 2002 |
| Abstract : Prince_2002_J.Gen.Physiol_120_369 |
| ESTHER : Prince_2002_J.Gen.Physiol_120_369 |
| PubMedSearch : Prince_2002_J.Gen.Physiol_120_369 |
| PubMedID: 12198092 |
| Title : Lysine scanning mutagenesis delineates structural model of the nicotinic receptor ligand binding domain - Sine_2002_J.Biol.Chem_277_29210 |
| Author(s) : Sine SM , Wang HL , Bren N |
| Ref : Journal of Biological Chemistry , 277 :29210 , 2002 |
| Abstract : Sine_2002_J.Biol.Chem_277_29210 |
| ESTHER : Sine_2002_J.Biol.Chem_277_29210 |
| PubMedSearch : Sine_2002_J.Biol.Chem_277_29210 |
| PubMedID: 12011092 |
| Title : The spectrum of congenital myasthenic syndromes - Engel_2002_Mol.Neurobiol_26_347 |
| Author(s) : Engel AG , Ohno K , Sine SM |
| Ref : Molecular Neurobiology , 26 :347 , 2002 |
| Abstract : Engel_2002_Mol.Neurobiol_26_347 |
| ESTHER : Engel_2002_Mol.Neurobiol_26_347 |
| PubMedSearch : Engel_2002_Mol.Neurobiol_26_347 |
| PubMedID: 12428764 |
| Title : Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1 - Ibanez-Tallon_2002_Neuron_33_893 |
| Author(s) : Ibanez-Tallon I , Miwa JM , Wang HL , Adams NC , Crabtree GW , Sine SM , Heintz N |
| Ref : Neuron , 33 :893 , 2002 |
| Abstract : Ibanez-Tallon_2002_Neuron_33_893 |
| ESTHER : Ibanez-Tallon_2002_Neuron_33_893 |
| PubMedSearch : Ibanez-Tallon_2002_Neuron_33_893 |
| PubMedID: 11906696 |
| Title : Subunit-selective contribution to channel gating of the M4 domain of the nicotinic receptor - Bouzat_2002_Biophys.J_82_1920 |
| Author(s) : Bouzat C , Gumilar F , del Carmen Esandi M , Sine SM |
| Ref : Biophysical Journal , 82 :1920 , 2002 |
| Abstract : Bouzat_2002_Biophys.J_82_1920 |
| ESTHER : Bouzat_2002_Biophys.J_82_1920 |
| PubMedSearch : Bouzat_2002_Biophys.J_82_1920 |
| PubMedID: 11916850 |
| Title : Hydrophobic pairwise interactions stabilize alpha-conotoxin MI in the muscle acetylcholine receptor binding site - Bren_2000_J.Biol.Chem_275_12692 |
| Author(s) : Bren N , Sine SM |
| Ref : Journal of Biological Chemistry , 275 :12692 , 2000 |
| Abstract : Bren_2000_J.Biol.Chem_275_12692 |
| ESTHER : Bren_2000_J.Biol.Chem_275_12692 |
| PubMedSearch : Bren_2000_J.Biol.Chem_275_12692 |
| PubMedID: 10777563 |
| Title : The extracellular linker of muscle acetylcholine receptor channels is a gating control element - Grosman_2000_J.Gen.Physiol_116_327 |
| Author(s) : Grosman C , Salamone FN , Sine SM , Auerbach A |
| Ref : Journal of General Physiology , 116 :327 , 2000 |
| Abstract : Grosman_2000_J.Gen.Physiol_116_327 |
| ESTHER : Grosman_2000_J.Gen.Physiol_116_327 |
| PubMedSearch : Grosman_2000_J.Gen.Physiol_116_327 |
| PubMedID: 10962011 |
| Title : Pairwise electrostatic interactions between alpha-neurotoxins and gamma, delta, and epsilon subunits of the nicotinic acetylcholine receptor - Osaka_2000_J.Biol.Chem_275_5478 |
| Author(s) : Osaka H , Malany S , Molles BE , Sine SM , Taylor P |
| Ref : Journal of Biological Chemistry , 275 :5478 , 2000 |
| Abstract : Osaka_2000_J.Biol.Chem_275_5478 |
| ESTHER : Osaka_2000_J.Biol.Chem_275_5478 |
| PubMedSearch : Osaka_2000_J.Biol.Chem_275_5478 |
| PubMedID: 10681526 |
| Title : Orientation of alpha-neurotoxin at the subunit interfaces of the nicotinic acetylcholine receptor - Malany_2000_Biochemistry_39_15388 |
| Author(s) : Malany S , Osaka H , Sine SM , Taylor P |
| Ref : Biochemistry , 39 :15388 , 2000 |
| Abstract : Malany_2000_Biochemistry_39_15388 |
| ESTHER : Malany_2000_Biochemistry_39_15388 |
| PubMedSearch : Malany_2000_Biochemistry_39_15388 |
| PubMedID: 11112524 |
| Title : Fundamental gating mechanism of nicotinic receptor channel revealed by mutation causing a congenital myasthenic syndrome - Wang_2000_J.Gen.Physiol_116_449 |
| Author(s) : Wang HL , Ohno K , Milone M , Brengman JM , Evoli A , Batocchi AP , Middleton LT , Christodoulou K , Engel AG , Sine SM |
| Ref : Journal of General Physiology , 116 :449 , 2000 |
| Abstract : Wang_2000_J.Gen.Physiol_116_449 |
| ESTHER : Wang_2000_J.Gen.Physiol_116_449 |
| PubMedSearch : Wang_2000_J.Gen.Physiol_116_449 |
| PubMedID: 10962020 |
| Title : Pairwise interactions between neuronal alpha(7) acetylcholine receptors and alpha-conotoxin PnIB - Quiram_2000_J.Biol.Chem_275_4889 |
| Author(s) : Quiram PA , McIntosh JM , Sine SM |
| Ref : Journal of Biological Chemistry , 275 :4889 , 2000 |
| Abstract : Quiram_2000_J.Biol.Chem_275_4889 |
| ESTHER : Quiram_2000_J.Biol.Chem_275_4889 |
| PubMedSearch : Quiram_2000_J.Biol.Chem_275_4889 |
| PubMedID: 10671525 |
| Title : Subunit interface selectivity of the alpha-neurotoxins for the nicotinic acetylcholine receptor - Osaka_1999_J.Biol.Chem_274_9581 |
| Author(s) : Osaka H , Malany S , Kanter J , Sine SM , Taylor P |
| Ref : Journal of Biological Chemistry , 274 :9581 , 1999 |
| Abstract : Osaka_1999_J.Biol.Chem_274_9581 |
| ESTHER : Osaka_1999_J.Biol.Chem_274_9581 |
| PubMedSearch : Osaka_1999_J.Biol.Chem_274_9581 |
| PubMedID: 10092644 |
| Title : Mutation causing congenital myasthenia reveals acetylcholine receptor beta\/delta subunit interaction essential for assembly - Quiram_1999_J.Clin.Invest_104_1403 |
| Author(s) : Quiram PA , Ohno K , Milone M , Patterson MC , Pruitt NJ , Brengman JM , Sine SM , Engel AG |
| Ref : J Clinical Investigation , 104 :1403 , 1999 |
| Abstract : Quiram_1999_J.Clin.Invest_104_1403 |
| ESTHER : Quiram_1999_J.Clin.Invest_104_1403 |
| PubMedSearch : Quiram_1999_J.Clin.Invest_104_1403 |
| PubMedID: 10562302 |
| Title : Congenital myasthenic syndromes: recent advances - Engel_1999_Arch.Neurol_56_163 |
| Author(s) : Engel AG , Ohno K , Sine SM |
| Ref : Archives of Neurology , 56 :163 , 1999 |
| Abstract : Engel_1999_Arch.Neurol_56_163 |
| ESTHER : Engel_1999_Arch.Neurol_56_163 |
| PubMedSearch : Engel_1999_Arch.Neurol_56_163 |
| PubMedID: 10025421 |
| Title : Acetylcholine receptor M3 domain: stereochemical and volume contributions to channel gating - Wang_1999_Nat.Neurosci_2_226 |
| Author(s) : Wang HL , Milone M , Ohno K , Shen XM , Tsujino A , Batocchi AP , Tonali P , Brengman J , Engel AG , Sine SM |
| Ref : Nat Neurosci , 2 :226 , 1999 |
| Abstract : Wang_1999_Nat.Neurosci_2_226 |
| ESTHER : Wang_1999_Nat.Neurosci_2_226 |
| PubMedSearch : Wang_1999_Nat.Neurosci_2_226 |
| PubMedID: 10195214 |
| Title : Acetylcholine and epibatidine binding to muscle acetylcholine receptors distinguish between concerted and uncoupled models - Prince_1999_J.Biol.Chem_274_19623 |
| Author(s) : Prince RJ , Sine SM |
| Ref : Journal of Biological Chemistry , 274 :19623 , 1999 |
| Abstract : Prince_1999_J.Biol.Chem_274_19623 |
| ESTHER : Prince_1999_J.Biol.Chem_274_19623 |
| PubMedSearch : Prince_1999_J.Biol.Chem_274_19623 |
| PubMedID: 10391899 |
| Title : Pairwise interactions between neuronal alpha7 acetylcholine receptors and alpha-conotoxin ImI - Quiram_1999_J.Biol.Chem_274_19517 |
| Author(s) : Quiram PA , Jones JJ , Sine SM |
| Ref : Journal of Biological Chemistry , 274 :19517 , 1999 |
| Abstract : Quiram_1999_J.Biol.Chem_274_19517 |
| ESTHER : Quiram_1999_J.Biol.Chem_274_19517 |
| PubMedSearch : Quiram_1999_J.Biol.Chem_274_19517 |
| PubMedID: 10391883 |
| Title : Residues at the subunit interfaces of the nicotinic acetylcholine receptor that contribute to alpha-conotoxin M1 binding - Sugiyama_1998_Mol.Pharmacol_53_787 |
| Author(s) : Sugiyama N , Marchot P , Kawanishi C , Osaka H , Molles BE , Sine SM , Taylor P |
| Ref : Molecular Pharmacology , 53 :787 , 1998 |
| Abstract : Sugiyama_1998_Mol.Pharmacol_53_787 |
| ESTHER : Sugiyama_1998_Mol.Pharmacol_53_787 |
| PubMedSearch : Sugiyama_1998_Mol.Pharmacol_53_787 |
| PubMedID: 9547372 |
| Title : Congenital myasthenic syndromes: experiments of nature - Engel_1998_J.Physiol.Paris_92_113 |
| Author(s) : Engel AG , Ohno K , Sine SM |
| Ref : Journal de Physiologie (Paris) , 92 :113 , 1998 |
| Abstract : Engel_1998_J.Physiol.Paris_92_113 |
| ESTHER : Engel_1998_J.Physiol.Paris_92_113 |
| PubMedSearch : Engel_1998_J.Physiol.Paris_92_113 |
| PubMedID: 9782453 |
| Title : Toxins selective for subunit interfaces as probes of nicotinic acetylcholine receptor structure - Taylor_1998_J.Physiol.Paris_92_79 |
| Author(s) : Taylor P , Osaka H , Molles BE , Sugiyama N , Marchot P , Ackermann EJ , Malany S , McArdle JJ , Sine SM , Tsigelny I |
| Ref : Journal de Physiologie (Paris) , 92 :79 , 1998 |
| Abstract : Taylor_1998_J.Physiol.Paris_92_79 |
| ESTHER : Taylor_1998_J.Physiol.Paris_92_79 |
| PubMedSearch : Taylor_1998_J.Physiol.Paris_92_79 |
| PubMedID: 9782448 |
| Title : Probing the structure of the ligand binding site on the muscle nicotinic receptor with Waglerin peptides - |
| Author(s) : Molles BE , Kline EF , Sine SM , McArdle JJ , Taylor P |
| Ref : Journal de Physiologie (Paris) , 92 :470 , 1998 |
| PubMedID: |
| Title : Binding orientation of thealpha-neurotoxins with the nicotinic acetylcholine receptor - |
| Author(s) : Osaka H , Ackermann EJ , Kanter J , Tsigelny I , Sine SM , Taylor P |
| Ref : Journal de Physiologie (Paris) , 92 :476 , 1998 |
| PubMedID: |
| Title : Molecular dissection of subunit interfaces in the nicotinic acetylcholine receptor - Sine_1998_J.Physiol.Paris_92_101 |
| Author(s) : Sine SM , Bren N , Quiram PA |
| Ref : Journal de Physiologie (Paris) , 92 :101 , 1998 |
| Abstract : Sine_1998_J.Physiol.Paris_92_101 |
| ESTHER : Sine_1998_J.Physiol.Paris_92_101 |
| PubMedSearch : Sine_1998_J.Physiol.Paris_92_101 |
| PubMedID: 9782451 |
| Title : Epibatidine activates muscle acetylcholine receptors with unique site selectivity - Prince_1998_Biophys.J_75_1817 |
| Author(s) : Prince RJ , Sine SM |
| Ref : Biophysical Journal , 75 :1817 , 1998 |
| Abstract : Prince_1998_Biophys.J_75_1817 |
| ESTHER : Prince_1998_Biophys.J_75_1817 |
| PubMedSearch : Prince_1998_Biophys.J_75_1817 |
| PubMedID: 9746523 |
| Title : Epibatidine binds with unique site and state selectivity to muscle nicotinic acetylcholine receptors - Prince_1998_J.Biol.Chem_273_7843 |
| Author(s) : Prince RJ , Sine SM |
| Ref : Journal of Biological Chemistry , 273 :7843 , 1998 |
| Abstract : Prince_1998_J.Biol.Chem_273_7843 |
| ESTHER : Prince_1998_J.Biol.Chem_273_7843 |
| PubMedSearch : Prince_1998_J.Biol.Chem_273_7843 |
| PubMedID: 9525877 |
| Title : Identification of residues in the neuronal alpha7 acetylcholine receptor that confer selectivity for conotoxin ImI - Quiram_1998_J.Biol.Chem_273_11001 |
| Author(s) : Quiram PA , Sine SM |
| Ref : Journal of Biological Chemistry , 273 :11001 , 1998 |
| Abstract : Quiram_1998_J.Biol.Chem_273_11001 |
| ESTHER : Quiram_1998_J.Biol.Chem_273_11001 |
| PubMedSearch : Quiram_1998_J.Biol.Chem_273_11001 |
| PubMedID: 9556580 |
| Title : Structural elements in alpha-conotoxin ImI essential for binding to neuronal alpha7 receptors - Quiram_1998_J.Biol.Chem_273_11007 |
| Author(s) : Quiram PA , Sine SM |
| Ref : Journal of Biological Chemistry , 273 :11007 , 1998 |
| Abstract : Quiram_1998_J.Biol.Chem_273_11007 |
| ESTHER : Quiram_1998_J.Biol.Chem_273_11007 |
| PubMedSearch : Quiram_1998_J.Biol.Chem_273_11007 |
| PubMedID: 9556581 |
| Title : Mode switching kinetics produced by a naturally occurring mutation in the cytoplasmic loop of the human acetylcholine receptor epsilon subunit - Milone_1998_Neuron_20_575 |
| Author(s) : Milone M , Wang HL , Ohno K , Prince R , Fukudome T , Shen XM , Brengman JM , Griggs RC , Sine SM , Engel AG |
| Ref : Neuron , 20 :575 , 1998 |
| Abstract : Milone_1998_Neuron_20_575 |
| ESTHER : Milone_1998_Neuron_20_575 |
| PubMedSearch : Milone_1998_Neuron_20_575 |
| PubMedID: 9539130 |
| Title : Congenital myasthenic syndromes due to heteroallelic nonsense\/missense mutations in the acetylcholine receptor epsilon subunit gene: identification and functional characterization of six new mutations - Ohno_1997_Hum.Mol.Genet_6_753 |
| Author(s) : Ohno K , Quiram PA , Milone M , Wang HL , Harper MC , Pruitt JN, 2nd , Brengman JM , Pao L , Fischbeck KH , Crawford TO , Sine SM , Engel AG |
| Ref : Hum Mol Genet , 6 :753 , 1997 |
| Abstract : Ohno_1997_Hum.Mol.Genet_6_753 |
| ESTHER : Ohno_1997_Hum.Mol.Genet_6_753 |
| PubMedSearch : Ohno_1997_Hum.Mol.Genet_6_753 |
| PubMedID: 9158150 |
| Title : A model of the nicotinic receptor extracellular domain based on sequence identity and residue location - Tsigelny_1997_Biophys.J_73_52 |
| Author(s) : Tsigelny I , Sugiyama N , Sine SM , Taylor P |
| Ref : Biophysical Journal , 73 :52 , 1997 |
| Abstract : Tsigelny_1997_Biophys.J_73_52 |
| ESTHER : Tsigelny_1997_Biophys.J_73_52 |
| PubMedSearch : Tsigelny_1997_Biophys.J_73_52 |
| PubMedID: 9199771 |
| Title : Identification of equivalent residues in the gamma, delta, and epsilon subunits of the nicotinic receptor that contribute to alpha-bungarotoxin binding - Sine_1997_J.Biol.Chem_272_23521 |
| Author(s) : Sine SM |
| Ref : Journal of Biological Chemistry , 272 :23521 , 1997 |
| Abstract : Sine_1997_J.Biol.Chem_272_23521 |
| ESTHER : Sine_1997_J.Biol.Chem_272_23521 |
| PubMedSearch : Sine_1997_J.Biol.Chem_272_23521 |
| PubMedID: 9295287 |
| Title : Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation - Wang_1997_J.Gen.Physiol_109_757 |
| Author(s) : Wang HL , Auerbach A , Bren N , Ohno K , Engel AG , Sine SM |
| Ref : Journal of General Physiology , 109 :757 , 1997 |
| Abstract : Wang_1997_J.Gen.Physiol_109_757 |
| ESTHER : Wang_1997_J.Gen.Physiol_109_757 |
| PubMedSearch : Wang_1997_J.Gen.Physiol_109_757 |
| PubMedID: 9222901 |
| Title : Slow-channel myasthenic syndrome caused by enhanced activation, desensitization, and agonist binding affinity attributable to mutation in the M2 domain of the acetylcholine receptor alpha subunit - Milone_1997_J.Neurosci_17_5651 |
| Author(s) : Milone M , Wang HL , Ohno K , Fukudome T , Pruitt JN , Bren N , Sine SM , Engel AG |
| Ref : Journal of Neuroscience , 17 :5651 , 1997 |
| Abstract : Milone_1997_J.Neurosci_17_5651 |
| ESTHER : Milone_1997_J.Neurosci_17_5651 |
| PubMedSearch : Milone_1997_J.Neurosci_17_5651 |
| PubMedID: 9221765 |
| Title : Identification of residues in the adult nicotinic acetylcholine receptor that confer selectivity for curariform antagonists - Bren_1997_J.Biol.Chem_272_30793 |
| Author(s) : Bren N , Sine SM |
| Ref : Journal of Biological Chemistry , 272 :30793 , 1997 |
| Abstract : Bren_1997_J.Biol.Chem_272_30793 |
| ESTHER : Bren_1997_J.Biol.Chem_272_30793 |
| PubMedSearch : Bren_1997_J.Biol.Chem_272_30793 |
| PubMedID: 9388220 |
| Title : End-plate acetylcholine receptor deficiency due to nonsense mutations in the epsilon subunit - Engel_1996_Ann.Neurol_40_810 |
| Author(s) : Engel AG , Ohno K , Bouzat C , Sine SM , Griggs RC |
| Ref : Annals of Neurology , 40 :810 , 1996 |
| Abstract : Engel_1996_Ann.Neurol_40_810 |
| ESTHER : Engel_1996_Ann.Neurol_40_810 |
| PubMedSearch : Engel_1996_Ann.Neurol_40_810 |
| PubMedID: 8957026 |
| Title : New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome - Engel_1996_Hum.Mol.Genet_5_1217 |
| Author(s) : Engel AG , Ohno K , Milone M , Wang HL , Nakano S , Bouzat C , Pruitt JN, 2nd , Hutchinson DO , Brengman JM , Bren N , Sieb JP , Sine SM |
| Ref : Hum Mol Genet , 5 :1217 , 1996 |
| Abstract : Engel_1996_Hum.Mol.Genet_5_1217 |
| ESTHER : Engel_1996_Hum.Mol.Genet_5_1217 |
| PubMedSearch : Engel_1996_Hum.Mol.Genet_5_1217 |
| PubMedID: 8872460 |
| Title : Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor epsilon subunit - Ohno_1996_Neuron_17_157 |
| Author(s) : Ohno K , Wang HL , Milone M , Bren N , Brengman JM , Nakano S , Quiram P , Pruitt JN , Sine SM , Engel AG |
| Ref : Neuron , 17 :157 , 1996 |
| Abstract : Ohno_1996_Neuron_17_157 |
| ESTHER : Ohno_1996_Neuron_17_157 |
| PubMedSearch : Ohno_1996_Neuron_17_157 |
| PubMedID: 8755487 |
| Title : Molecular dissection of subunit interfaces in the acetylcholine receptor. Identification of residues that determine agonist selectivity - Prince_1996_J.Biol.Chem_271_25770 |
| Author(s) : Prince RJ , Sine SM |
| Ref : Journal of Biological Chemistry , 271 :25770 , 1996 |
| Abstract : Prince_1996_J.Biol.Chem_271_25770 |
| ESTHER : Prince_1996_J.Biol.Chem_271_25770 |
| PubMedSearch : Prince_1996_J.Biol.Chem_271_25770 |
| PubMedID: 8824205 |
| Title : Asymmetric contribution of the conserved disulfide loop to subunit oligomerization and assembly of the nicotinic acetylcholine receptor - Fu_1996_J.Biol.Chem_271_31479 |
| Author(s) : Fu DX , Sine SM |
| Ref : Journal of Biological Chemistry , 271 :31479 , 1996 |
| Abstract : Fu_1996_J.Biol.Chem_271_31479 |
| ESTHER : Fu_1996_J.Biol.Chem_271_31479 |
| PubMedSearch : Fu_1996_J.Biol.Chem_271_31479 |
| PubMedID: 8940161 |
| Title : Intersubunit contacts governing assembly of the mammalian nicotinic acetylcholine receptor - Kreienkamp_1995_Neuron_14_635 |
| Author(s) : Kreienkamp HJ , Maeda RK , Sine SM , Taylor P |
| Ref : Neuron , 14 :635 , 1995 |
| Abstract : Kreienkamp_1995_Neuron_14_635 |
| ESTHER : Kreienkamp_1995_Neuron_14_635 |
| PubMedSearch : Kreienkamp_1995_Neuron_14_635 |
| PubMedID: 7695910 |
| Title : Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit - Ohno_1995_Proc.Natl.Acad.Sci.U.S.A_92_758 |
| Author(s) : Ohno K , Hutchinson DO , Milone M , Brengman JM , Bouzat C , Sine SM , Engel AG |
| Ref : Proc Natl Acad Sci U S A , 92 :758 , 1995 |
| Abstract : Ohno_1995_Proc.Natl.Acad.Sci.U.S.A_92_758 |
| ESTHER : Ohno_1995_Proc.Natl.Acad.Sci.U.S.A_92_758 |
| PubMedSearch : Ohno_1995_Proc.Natl.Acad.Sci.U.S.A_92_758 |
| PubMedID: 7531341 |
| Title : Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity - Sine_1995_Neuron_15_205 |
| Author(s) : Sine SM , Kreienkamp HJ , Bren N , Maeda RK , Taylor P |
| Ref : Neuron , 15 :205 , 1995 |
| Abstract : Sine_1995_Neuron_15_205 |
| ESTHER : Sine_1995_Neuron_15_205 |
| PubMedSearch : Sine_1995_Neuron_15_205 |
| PubMedID: 7619523 |
| Title : Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity - Sine_1995_Neuron_15_229 |
| Author(s) : Sine SM , Ohno K , Bouzat C , Auerbach A , Milone M , Pruitt JN , Engel AG |
| Ref : Neuron , 15 :229 , 1995 |
| Abstract : Sine_1995_Neuron_15_229 |
| ESTHER : Sine_1995_Neuron_15_229 |
| PubMedSearch : Sine_1995_Neuron_15_229 |
| PubMedID: 7619526 |
| Title : Glycosylation sites selectively interfere with alpha-toxin binding to the nicotinic acetylcholine receptor - Kreienkamp_1994_J.Biol.Chem_269_8108 |
| Author(s) : Kreienkamp HJ , Sine SM , Maeda RK , Taylor P |
| Ref : Journal of Biological Chemistry , 269 :8108 , 1994 |
| Abstract : Kreienkamp_1994_J.Biol.Chem_269_8108 |
| ESTHER : Kreienkamp_1994_J.Biol.Chem_269_8108 |
| PubMedSearch : Kreienkamp_1994_J.Biol.Chem_269_8108 |
| PubMedID: 7907588 |
| Title : Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists - Sine_1994_J.Biol.Chem_269_8808 |
| Author(s) : Sine SM , Quiram P , Papanikolaou F , Kreienkamp HJ , Taylor P |
| Ref : Journal of Biological Chemistry , 269 :8808 , 1994 |
| Abstract : Sine_1994_J.Biol.Chem_269_8808 |
| ESTHER : Sine_1994_J.Biol.Chem_269_8808 |
| PubMedSearch : Sine_1994_J.Biol.Chem_269_8808 |
| PubMedID: 8132615 |
| Title : Competitive antagonists bridge the alpha-gamma subunit interface of the acetylcholine receptor through quaternary ammonium-aromatic interactions - Fu_1994_J.Biol.Chem_269_26152 |
| Author(s) : Fu DX , Sine SM |
| Ref : Journal of Biological Chemistry , 269 :26152 , 1994 |
| Abstract : Fu_1994_J.Biol.Chem_269_26152 |
| ESTHER : Fu_1994_J.Biol.Chem_269_26152 |
| PubMedSearch : Fu_1994_J.Biol.Chem_269_26152 |
| PubMedID: 7929328 |
| Title : Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors - Bouzat_1994_Neuron_13_1395 |
| Author(s) : Bouzat C , Bren N , Sine SM |
| Ref : Neuron , 13 :1395 , 1994 |
| Abstract : Bouzat_1994_Neuron_13_1395 |
| ESTHER : Bouzat_1994_Neuron_13_1395 |
| PubMedSearch : Bouzat_1994_Neuron_13_1395 |
| PubMedID: 7993630 |
| Title : Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity - Sine_1993_Proc.Natl.Acad.Sci.U.S.A_90_9436 |
| Author(s) : Sine SM |
| Ref : Proc Natl Acad Sci U S A , 90 :9436 , 1993 |
| Abstract : Sine_1993_Proc.Natl.Acad.Sci.U.S.A_90_9436 |
| ESTHER : Sine_1993_Proc.Natl.Acad.Sci.U.S.A_90_9436 |
| PubMedSearch : Sine_1993_Proc.Natl.Acad.Sci.U.S.A_90_9436 |
| PubMedID: 8415719 |
| Title : Gamma- and delta-subunits regulate the affinity and the cooperativity of ligand binding to the acetylcholine receptor - Sine_1991_J.Biol.Chem_266_19369 |
| Author(s) : Sine SM , Claudio T |
| Ref : Journal of Biological Chemistry , 266 :19369 , 1991 |
| Abstract : Sine_1991_J.Biol.Chem_266_19369 |
| ESTHER : Sine_1991_J.Biol.Chem_266_19369 |
| PubMedSearch : Sine_1991_J.Biol.Chem_266_19369 |
| PubMedID: 1680865 |
| Title : Stable expression of the mouse nicotinic acetylcholine receptor in mouse fibroblasts. Comparison of receptors in native and transfected cells - Sine_1991_J.Biol.Chem_266_13679 |
| Author(s) : Sine SM , Claudio T |
| Ref : Journal of Biological Chemistry , 266 :13679 , 1991 |
| Abstract : Sine_1991_J.Biol.Chem_266_13679 |
| ESTHER : Sine_1991_J.Biol.Chem_266_13679 |
| PubMedSearch : Sine_1991_J.Biol.Chem_266_13679 |
| PubMedID: 1713208 |
| Title : Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities - Sine_1990_J.Gen.Physiol_96_395 |
| Author(s) : Sine SM , Claudio T , Sigworth FJ |
| Ref : Journal of General Physiology , 96 :395 , 1990 |
| Abstract : Sine_1990_J.Gen.Physiol_96_395 |
| ESTHER : Sine_1990_J.Gen.Physiol_96_395 |
| PubMedSearch : Sine_1990_J.Gen.Physiol_96_395 |
| PubMedID: 1698917 |
| Title : Functional properties of human skeletal muscle acetylcholine receptors expressed by the TE671 cell line - Sine_1988_J.Biol.Chem_263_18052 |
| Author(s) : Sine SM |
| Ref : Journal of Biological Chemistry , 263 :18052 , 1988 |
| Abstract : Sine_1988_J.Biol.Chem_263_18052 |
| ESTHER : Sine_1988_J.Biol.Chem_263_18052 |
| PubMedSearch : Sine_1988_J.Biol.Chem_263_18052 |
| PubMedID: 2461364 |
| Title : Function of nicotinic acetylcholine receptors - Steinbach_1987_Soc.Gen.Physiol.Ser_41_19 |
| Author(s) : Steinbach JH , Sine SM |
| Ref : Soc Gen Physiol Ser , 41 :19 , 1987 |
| Abstract : Steinbach_1987_Soc.Gen.Physiol.Ser_41_19 |
| ESTHER : Steinbach_1987_Soc.Gen.Physiol.Ser_41_19 |
| PubMedSearch : Steinbach_1987_Soc.Gen.Physiol.Ser_41_19 |
| PubMedID: 2436310 |
| Title : Genetic reconstitution of functional acetylcholine receptor channels in mouse fibroblasts - Claudio_1987_Science_238_1688 |
| Author(s) : Claudio T , Green WN , Hartman DS , Hayden D , Paulson HL , Sigworth FJ , Sine SM , Swedlund A |
| Ref : Science , 238 :1688 , 1987 |
| Abstract : Claudio_1987_Science_238_1688 |
| ESTHER : Claudio_1987_Science_238_1688 |
| PubMedSearch : Claudio_1987_Science_238_1688 |
| PubMedID: 3686008 |
| Title : Data transformations for improved display and fitting of single-channel dwell time histograms - Sigworth_1987_Biophys.J_52_1047 |
| Author(s) : Sigworth FJ , Sine SM |
| Ref : Biophysical Journal , 52 :1047 , 1987 |
| Abstract : Sigworth_1987_Biophys.J_52_1047 |
| ESTHER : Sigworth_1987_Biophys.J_52_1047 |
| PubMedSearch : Sigworth_1987_Biophys.J_52_1047 |
| PubMedID: 2447968 |
| Title : Activation of acetylcholine receptors on clonal mammalian BC3H-1 cells by high concentrations of agonist - Sine_1987_J.Physiol_385_325 |
| Author(s) : Sine SM , Steinbach JH |
| Ref : The Journal of Physiology , 385 :325 , 1987 |
| Abstract : Sine_1987_J.Physiol_385_325 |
| ESTHER : Sine_1987_J.Physiol_385_325 |
| PubMedSearch : Sine_1987_J.Physiol_385_325 |
| PubMedID: 2443668 |
| Title : Acetylcholine receptor activation by a site-selective ligand: nature of brief open and closed states in BC3H-1 cells - Sine_1986_J.Physiol_370_357 |
| Author(s) : Sine SM , Steinbach JH |
| Ref : The Journal of Physiology , 370 :357 , 1986 |
| Abstract : Sine_1986_J.Physiol_370_357 |
| ESTHER : Sine_1986_J.Physiol_370_357 |
| PubMedSearch : Sine_1986_J.Physiol_370_357 |
| PubMedID: 2420977 |
| Title : Activation of acetylcholine receptors on clonal mammalian BC3H-1 cells by low concentrations of agonist - Sine_1986_J.Physiol_373_129 |
| Author(s) : Sine SM , Steinbach JH |
| Ref : The Journal of Physiology , 373 :129 , 1986 |
| Abstract : Sine_1986_J.Physiol_373_129 |
| ESTHER : Sine_1986_J.Physiol_373_129 |
| PubMedSearch : Sine_1986_J.Physiol_373_129 |
| PubMedID: 2427693 |
| Title : Activation of a nicotinic acetylcholine receptor - Sine_1984_Biophys.J_45_175 |
| Author(s) : Sine SM , Steinbach JH |
| Ref : Biophysical Journal , 45 :175 , 1984 |
| Abstract : Sine_1984_Biophys.J_45_175 |
| ESTHER : Sine_1984_Biophys.J_45_175 |
| PubMedSearch : Sine_1984_Biophys.J_45_175 |
| PubMedID: 6324901 |
| Title : Agonists block currents through acetylcholine receptor channels - Sine_1984_Biophys.J_46_277 |
| Author(s) : Sine SM , Steinbach JH |
| Ref : Biophysical Journal , 46 :277 , 1984 |
| Abstract : Sine_1984_Biophys.J_46_277 |
| ESTHER : Sine_1984_Biophys.J_46_277 |
| PubMedSearch : Sine_1984_Biophys.J_46_277 |
| PubMedID: 6478036 |
| Title : The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin - Sine_1980_J.Biol.Chem_255_10144 |
| Author(s) : Sine SM , Taylor P |
| Ref : Journal of Biological Chemistry , 255 :10144 , 1980 |
| Abstract : Sine_1980_J.Biol.Chem_255_10144 |
| ESTHER : Sine_1980_J.Biol.Chem_255_10144 |
| PubMedSearch : Sine_1980_J.Biol.Chem_255_10144 |
| PubMedID: 7430118 |
| Title : Studies on vitamin D and its analogs. VI. 3-deoxy-A-homovitamin D3, a model synthesis - |
| Author(s) : Sine SM , Conklin TE , Okamura WH |
| Ref : J Org Chem , 39 :3797 , 1974 |
| PubMedID: 4377157 |
| Title : Vitamin D in solution: conformations of vitamin D3, 1alpha,25-dihydroxyvitamin D3, and dihydrotachysterol3 - Wing_1974_Science_186_939 |
| Author(s) : Wing RM , Okamura WH , Pirio MR , Sine SM , Norman AW |
| Ref : Science , 186 :939 , 1974 |
| Abstract : Wing_1974_Science_186_939 |
| ESTHER : Wing_1974_Science_186_939 |
| PubMedSearch : Wing_1974_Science_186_939 |
| PubMedID: 4377759 |