Full name : Sher Emanuele
First name : Emanuele
Mail : Lilly Research Centre, Eli Lilly and Company Limited, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey GU20 6PH
Zip Code :
City :
Country : United Kingdom
Email :
Phone :
Fax :
Website :
Directory :
| Title : Forebrain-selective AMPA-receptor antagonism guided by TARP gamma-8 as an antiepileptic mechanism - Kato_2016_Nat.Med_22_1496 |
| Author(s) : Kato AS , Burris KD , Gardinier KM , Gernert DL , Porter WJ , Reel J , Ding C , Tu Y , Schober DA , Lee MR , Heinz BA , Fitch TE , Gleason SD , Catlow JT , Yu H , Fitzjohn SM , Pasqui F , Wang H , Qian Y , Sher E , Zwart R , Wafford KA , Rasmussen K , Ornstein PL , Isaac JT , Nisenbaum ES , Bredt DS , Witkin JM |
| Ref : Nat Med , 22 :1496 , 2016 |
| Abstract : Kato_2016_Nat.Med_22_1496 |
| ESTHER : Kato_2016_Nat.Med_22_1496 |
| PubMedSearch : Kato_2016_Nat.Med_22_1496 |
| PubMedID: 27820603 |
| Title : alpha7 and beta2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties - Thomsen_2015_PLoS.One_10_e0130572 |
| Author(s) : Thomsen MS , Zwart R , Ursu D , Jensen MM , Pinborg LH , Gilmour G , Wu J , Sher E , Mikkelsen JD |
| Ref : PLoS ONE , 10 :e0130572 , 2015 |
| Abstract : Thomsen_2015_PLoS.One_10_e0130572 |
| ESTHER : Thomsen_2015_PLoS.One_10_e0130572 |
| PubMedSearch : Thomsen_2015_PLoS.One_10_e0130572 |
| PubMedID: 26086615 |
| Title : Unique pharmacology of heteromeric alpha7beta2 nicotinic acetylcholine receptors expressed in Xenopus laevis oocytes - Zwart_2014_Eur.J.Pharmacol_726C_77 |
| Author(s) : Zwart R , Strotton M , Ching J , Astles PC , Sher E |
| Ref : European Journal of Pharmacology , 726C :77 , 2014 |
| Abstract : Zwart_2014_Eur.J.Pharmacol_726C_77 |
| ESTHER : Zwart_2014_Eur.J.Pharmacol_726C_77 |
| PubMedSearch : Zwart_2014_Eur.J.Pharmacol_726C_77 |
| PubMedID: 24485886 |
| Title : Contrasting properties of alpha7-selective orthosteric and allosteric agonists examined on native nicotinic acetylcholine receptors - Gill_2013_PLoS.One_8_e55047 |
| Author(s) : Gill JK , Chatzidaki A , Ursu D , Sher E , Millar NS |
| Ref : PLoS ONE , 8 :e55047 , 2013 |
| Abstract : Gill_2013_PLoS.One_8_e55047 |
| ESTHER : Gill_2013_PLoS.One_8_e55047 |
| PubMedSearch : Gill_2013_PLoS.One_8_e55047 |
| PubMedID: 23383051 |
| Title : A series of alpha7 nicotinic acetylcholine receptor allosteric modulators with close chemical similarity but diverse pharmacological properties - Gill_2012_Mol.Pharmacol_81_710 |
| Author(s) : Gill JK , Dhankher P , Sheppard TD , Sher E , Millar NS |
| Ref : Molecular Pharmacology , 81 :710 , 2012 |
| Abstract : Gill_2012_Mol.Pharmacol_81_710 |
| ESTHER : Gill_2012_Mol.Pharmacol_81_710 |
| PubMedSearch : Gill_2012_Mol.Pharmacol_81_710 |
| PubMedID: 22328718 |
| Title : Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site - Gill_2011_Proc.Natl.Acad.Sci.U.S.A_108_5867 |
| Author(s) : Gill JK , Savolainen M , Young GT , Zwart R , Sher E , Millar NS |
| Ref : Proc Natl Acad Sci U S A , 108 :5867 , 2011 |
| Abstract : Gill_2011_Proc.Natl.Acad.Sci.U.S.A_108_5867 |
| ESTHER : Gill_2011_Proc.Natl.Acad.Sci.U.S.A_108_5867 |
| PubMedSearch : Gill_2011_Proc.Natl.Acad.Sci.U.S.A_108_5867 |
| PubMedID: 21436053 |
| Title : Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors - Zwart_2008_Mol.Pharmacol_73_1838 |
| Author(s) : Zwart R , Carbone AL , Moroni M , Bermudez I , Mogg AJ , Folly EA , Broad LM , Williams AC , Zhang D , Ding C , Heinz BA , Sher E |
| Ref : Molecular Pharmacology , 73 :1838 , 2008 |
| Abstract : Zwart_2008_Mol.Pharmacol_73_1838 |
| ESTHER : Zwart_2008_Mol.Pharmacol_73_1838 |
| PubMedSearch : Zwart_2008_Mol.Pharmacol_73_1838 |
| PubMedID: 18367540 |
| Title : Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site - Young_2008_Proc.Natl.Acad.Sci.U.S.A_105_14686 |
| Author(s) : Young GT , Zwart R , Walker AS , Sher E , Millar NS |
| Ref : Proc Natl Acad Sci U S A , 105 :14686 , 2008 |
| Abstract : Young_2008_Proc.Natl.Acad.Sci.U.S.A_105_14686 |
| ESTHER : Young_2008_Proc.Natl.Acad.Sci.U.S.A_105_14686 |
| PubMedSearch : Young_2008_Proc.Natl.Acad.Sci.U.S.A_105_14686 |
| PubMedID: 18791069 |
| Title : Species selectivity of a nicotinic acetylcholine receptor agonist is conferred by two adjacent extracellular beta4 amino acids that are implicated in the coupling of binding to channel gating - Young_2007_Mol.Pharmacol_71_389 |
| Author(s) : Young GT , Broad LM , Zwart R , Astles PC , Bodkin M , Sher E , Millar NS |
| Ref : Molecular Pharmacology , 71 :389 , 2007 |
| Abstract : Young_2007_Mol.Pharmacol_71_389 |
| ESTHER : Young_2007_Mol.Pharmacol_71_389 |
| PubMedSearch : Young_2007_Mol.Pharmacol_71_389 |
| PubMedID: 17065235 |
| Title : Chaperone protein 14-3-3 and protein kinase A increase the relative abundance of low agonist sensitivity human alpha 4 beta 2 nicotinic acetylcholine receptors in Xenopus oocytes - Exley_2006_J.Neurochem_98_876 |
| Author(s) : Exley R , Moroni M , Sasdelli F , Houlihan LM , Lukas RJ , Sher E , Zwart R , Bermudez I |
| Ref : Journal of Neurochemistry , 98 :876 , 2006 |
| Abstract : Exley_2006_J.Neurochem_98_876 |
| ESTHER : Exley_2006_J.Neurochem_98_876 |
| PubMedSearch : Exley_2006_J.Neurochem_98_876 |
| PubMedID: 16787419 |
| Title : Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators - Broad_2006_J.Pharmacol.Exp.Ther_318_1108 |
| Author(s) : Broad LM , Zwart R , Pearson KH , Lee M , Wallace L , McPhie GI , Emkey R , Hollinshead SP , Dell CP , Baker SR , Sher E |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 318 :1108 , 2006 |
| Abstract : Broad_2006_J.Pharmacol.Exp.Ther_318_1108 |
| ESTHER : Broad_2006_J.Pharmacol.Exp.Ther_318_1108 |
| PubMedSearch : Broad_2006_J.Pharmacol.Exp.Ther_318_1108 |
| PubMedID: 16738207 |
| Title : Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation - Gotti_2006_Neurobiol.Dis_23_481 |
| Author(s) : Gotti C , Moretti M , Bohr I , Ziabreva I , Vailati S , Longhi R , Riganti L , Gaimarri A , McKeith IG , Perry RH , Aarsland D , Larsen JP , Sher E , Beattie R , Clementi F , Court JA |
| Ref : Neurobiol Dis , 23 :481 , 2006 |
| Abstract : Gotti_2006_Neurobiol.Dis_23_481 |
| ESTHER : Gotti_2006_Neurobiol.Dis_23_481 |
| PubMedSearch : Gotti_2006_Neurobiol.Dis_23_481 |
| PubMedID: 16759874 |
| Title : alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine - Moroni_2006_Mol.Pharmacol_70_755 |
| Author(s) : Moroni M , Zwart R , Sher E , Cassels BK , Bermudez I |
| Ref : Molecular Pharmacology , 70 :755 , 2006 |
| Abstract : Moroni_2006_Mol.Pharmacol_70_755 |
| ESTHER : Moroni_2006_Mol.Pharmacol_70_755 |
| PubMedSearch : Moroni_2006_Mol.Pharmacol_70_755 |
| PubMedID: 16720757 |
| Title : 5-I A-85380 and TC-2559 differentially activate heterologously expressed alpha4beta2 nicotinic receptors - Zwart_2006_Eur.J.Pharmacol_539_10 |
| Author(s) : Zwart R , Broad LM , Xi Q , Lee M , Moroni M , Bermudez I , Sher E |
| Ref : European Journal of Pharmacology , 539 :10 , 2006 |
| Abstract : Zwart_2006_Eur.J.Pharmacol_539_10 |
| ESTHER : Zwart_2006_Eur.J.Pharmacol_539_10 |
| PubMedSearch : Zwart_2006_Eur.J.Pharmacol_539_10 |
| PubMedID: 16674940 |
| Title : Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors - Exley_2005_Br.J.Pharmacol_146_15 |
| Author(s) : Exley R , Iturriaga-Vasquez P , Lukas RJ , Sher E , Cassels BK , Bermudez I |
| Ref : British Journal of Pharmacology , 146 :15 , 2005 |
| Abstract : Exley_2005_Br.J.Pharmacol_146_15 |
| ESTHER : Exley_2005_Br.J.Pharmacol_146_15 |
| PubMedSearch : Exley_2005_Br.J.Pharmacol_146_15 |
| PubMedID: 15980871 |
| Title : Pharmacological properties of alpha 9 alpha 10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras - Baker_2004_Mol.Pharmacol_65_453 |
| Author(s) : Baker ER , Zwart R , Sher E , Millar NS |
| Ref : Molecular Pharmacology , 65 :453 , 2004 |
| Abstract : Baker_2004_Mol.Pharmacol_65_453 |
| ESTHER : Baker_2004_Mol.Pharmacol_65_453 |
| PubMedSearch : Baker_2004_Mol.Pharmacol_65_453 |
| PubMedID: 14742688 |
| Title : Brain penetration and behavioral properties of a potent alpha7 nicotinic acetylcholine receptor agonist in the rat. - |
| Author(s) : Moore NA , McKinzie DL , Mitchell SN , Keenan M , Dobson DR , Wishart G , Neill MO , Murray TK , Tree B , Iyengar S , Hart J , Shaw D , Simmons RMA , Kalra AB , Miles C , Conway M , Boot JR , Baker SR , Sher E , Tricklebank MD , O'Neill M |
| Ref : Cholinergic Mechanisms, CRC Press :649 , 2004 |
| PubMedID: |
| Title : Stable expression and characterisation of a human alpha 7 nicotinic subunit chimera: a tool for functional high-throughput screening - Craig_2004_Eur.J.Pharmacol_502_31 |
| Author(s) : Craig PJ , Bose S , Zwart R , Beattie RE , Folly EA , Johnson LR , Bell E , Evans NM , Benedetti G , Pearson KH , McPhie GI , Volsen SG , Millar NS , Sher E , Broad LM |
| Ref : European Journal of Pharmacology , 502 :31 , 2004 |
| Abstract : Craig_2004_Eur.J.Pharmacol_502_31 |
| ESTHER : Craig_2004_Eur.J.Pharmacol_502_31 |
| PubMedSearch : Craig_2004_Eur.J.Pharmacol_502_31 |
| PubMedID: 15464087 |
| Title : Common structural and pharmacological properties of serotonin 5-HT3 receptors and alpha7 nicotinic acetylcholine receptors. - |
| Author(s) : Zwart R , Bodkin M , Broad LM , De Filippi G , Craig PJ , Baldwinson T , Benedetti G , Felthouse C , McPhie GI , Pearson KH , Sher E |
| Ref : Cholinergic Mechanisms, CRC Press :309 , 2004 |
| PubMedID: |
| Title : Expression and functional characterisation of a human chimeric nicotinic receptor with alpha6beta4 properties - Evans_2003_Eur.J.Pharmacol_466_31 |
| Author(s) : Evans NM , Bose S , Benedetti G , Zwart R , Pearson KH , McPhie GI , Craig PJ , Benton JP , Volsen SG , Sher E , Broad LM |
| Ref : European Journal of Pharmacology , 466 :31 , 2003 |
| Abstract : Evans_2003_Eur.J.Pharmacol_466_31 |
| ESTHER : Evans_2003_Eur.J.Pharmacol_466_31 |
| PubMedSearch : Evans_2003_Eur.J.Pharmacol_466_31 |
| PubMedID: 12679139 |
| Title : PSAB-OFP, a selective alpha 7 nicotinic receptor agonist, is also a potent agonist of the 5-HT3 receptor - Broad_2002_Eur.J.Pharmacol_452_137 |
| Author(s) : Broad LM , Felthouse C , Zwart R , McPhie GI , Pearson KH , Craig PJ , Wallace L , Broadmore RJ , Boot JR , Keenan M , Baker SR , Sher E |
| Ref : European Journal of Pharmacology , 452 :137 , 2002 |
| Abstract : Broad_2002_Eur.J.Pharmacol_452_137 |
| ESTHER : Broad_2002_Eur.J.Pharmacol_452_137 |
| PubMedSearch : Broad_2002_Eur.J.Pharmacol_452_137 |
| PubMedID: 12354563 |
| Title : Regulation of GABA release by nicotinic acetylcholine receptors in the neonatal rat hippocampus - Maggi_2001_J.Physiol_536_89 |
| Author(s) : Maggi L , Sher E , Cherubini E |
| Ref : The Journal of Physiology , 536 :89 , 2001 |
| Abstract : Maggi_2001_J.Physiol_536_89 |
| ESTHER : Maggi_2001_J.Physiol_536_89 |
| PubMedSearch : Maggi_2001_J.Physiol_536_89 |
| PubMedID: 11579159 |
| Title : Distribution of the voltage-dependent calcium channel alpha1G subunit mRNA and protein throughout the mature rat brain - Craig_1999_Eur.J.Neurosci_11_2949 |
| Author(s) : Craig PJ , Beattie RE , Folly EA , Banerjee MD , Reeves MB , Priestley JV , Carney SL , Sher E , Perez-Reyes E , Volsen SG |
| Ref : European Journal of Neuroscience , 11 :2949 , 1999 |
| Abstract : Craig_1999_Eur.J.Neurosci_11_2949 |
| ESTHER : Craig_1999_Eur.J.Neurosci_11_2949 |
| PubMedSearch : Craig_1999_Eur.J.Neurosci_11_2949 |
| PubMedID: 10457190 |
| Title : Acetylcholine nicotinic receptor: a key molecule for the pathogenesis of myasthenia gravis - |
| Author(s) : Sher E , Gotti C , Clementi F |
| Ref : Annali dell Istituto Superiore di Sanita , 24 :103 , 1988 |
| PubMedID: 3289434 |
| Title : Intracellular calcium homeostasis in a human neuroblastoma cell line: modulation by depolarization, cholinergic receptors, and alpha-latrotoxin - Sher_1988_J.Neurochem_50_1708 |
| Author(s) : Sher E , Gotti C , Pandiella A , Madeddu L , Clementi F |
| Ref : Journal of Neurochemistry , 50 :1708 , 1988 |
| Abstract : Sher_1988_J.Neurochem_50_1708 |
| ESTHER : Sher_1988_J.Neurochem_50_1708 |
| PubMedSearch : Sher_1988_J.Neurochem_50_1708 |
| PubMedID: 2453611 |
| Title : The nicotinic receptors in the nervous system - |
| Author(s) : Gotti C , Sher E , Chini B , Fornasari D , Esparis Ogando A , Clementi F |
| Ref : Pharmacol Res Commun , 20 :637 , 1988 |
| PubMedID: 3062640 |
| Title : Effects of long-term in vitro exposure to aluminum, cadmium or lead on differentiation and cholinergic receptor expression in a human neuroblastoma cell line - Gotti_1987_Cell.Biol.Toxicol_3_431 |
| Author(s) : Gotti C , Cabrini D , Sher E , Clementi F |
| Ref : Cell Biol Toxicol , 3 :431 , 1987 |
| Abstract : Gotti_1987_Cell.Biol.Toxicol_3_431 |
| ESTHER : Gotti_1987_Cell.Biol.Toxicol_3_431 |
| PubMedSearch : Gotti_1987_Cell.Biol.Toxicol_3_431 |
| PubMedID: 3507265 |
| Title : Cholinergic receptors, ion channels, neurotransmitter synthesis, and neurite outgrowth are independently regulated during the in vitro differentiation of a human neuroblastoma cell line - Gotti_1987_Differentiation_34_144 |
| Author(s) : Gotti C , Sher E , Cabrini D , Bondiolotti G , Wanke E , Mancinelli E , Clementi F |
| Ref : Differentiation , 34 :144 , 1987 |
| Abstract : Gotti_1987_Differentiation_34_144 |
| ESTHER : Gotti_1987_Differentiation_34_144 |
| PubMedSearch : Gotti_1987_Differentiation_34_144 |
| PubMedID: 2442054 |
| Title : Acetylcholine operated ion channel and alpha-bungarotoxin binding site in a human neuroblastoma cell line reside on different molecules - Gotti_1986_Biochem.Biophys.Res.Commun_137_1141 |
| Author(s) : Gotti C , Wanke E , Sher E , Fornasari D , Cabrini D , Clementi F |
| Ref : Biochemical & Biophysical Research Communications , 137 :1141 , 1986 |
| Abstract : Gotti_1986_Biochem.Biophys.Res.Commun_137_1141 |
| ESTHER : Gotti_1986_Biochem.Biophys.Res.Commun_137_1141 |
| PubMedSearch : Gotti_1986_Biochem.Biophys.Res.Commun_137_1141 |
| PubMedID: 2425806 |
| Title : Pharmacological characterization of cholinergic receptors in a human neuroblastoma cell line - Clementi_1986_J.Neurochem_47_291 |
| Author(s) : Clementi F , Cabrini D , Gotti C , Sher E |
| Ref : Journal of Neurochemistry , 47 :291 , 1986 |
| Abstract : Clementi_1986_J.Neurochem_47_291 |
| ESTHER : Clementi_1986_J.Neurochem_47_291 |
| PubMedSearch : Clementi_1986_J.Neurochem_47_291 |
| PubMedID: 3711905 |