Full name : Shannon Harlan E
First name : Harlan E
Mail : Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285
Zip Code :
City :
Country : USA
Email : h.shannon@lilly.com
Phone :
Fax :
Website :
Directory :
| Title : Effects of antiepileptic drugs on learning as assessed by a repeated acquisition of response sequences task in rats - Shannon_2007_Epilepsy.Behav_10_16 |
| Author(s) : Shannon HE , Love PL |
| Ref : Epilepsy Behav , 10 :16 , 2007 |
| Abstract : Shannon_2007_Epilepsy.Behav_10_16 |
| ESTHER : Shannon_2007_Epilepsy.Behav_10_16 |
| PubMedSearch : Shannon_2007_Epilepsy.Behav_10_16 |
| PubMedID: 17174158 |
| Title : A non-spatial, stimulus-comparison working memory task in rats and disruption by scopolamine - Shannon_2007_Neurosci_145_955 |
| Author(s) : Shannon HE , Yang L |
| Ref : Neuroscience , 145 :955 , 2007 |
| Abstract : Shannon_2007_Neurosci_145_955 |
| ESTHER : Shannon_2007_Neurosci_145_955 |
| PubMedSearch : Shannon_2007_Neurosci_145_955 |
| PubMedID: 17303343 |
| Title : Effects of biasing the location of stimulus presentation, and the muscarinic cholinergic receptor antagonist scopolamine, on performance of a 5-choice serial reaction time attention task in rats - Shannon_2006_Behav.Pharmacol_17_71 |
| Author(s) : Shannon HE , Eberle EL |
| Ref : Behav Pharmacol , 17 :71 , 2006 |
| Abstract : Shannon_2006_Behav.Pharmacol_17_71 |
| ESTHER : Shannon_2006_Behav.Pharmacol_17_71 |
| PubMedSearch : Shannon_2006_Behav.Pharmacol_17_71 |
| PubMedID: 16377965 |
| Title : The seizure-related phenotype of brain-derived neurotrophic factor knockdown mice - Barton_2005_Neurosci_136_563 |
| Author(s) : Barton ME , Shannon HE |
| Ref : Neuroscience , 136 :563 , 2005 |
| Abstract : Barton_2005_Neurosci_136_563 |
| ESTHER : Barton_2005_Neurosci_136_563 |
| PubMedSearch : Barton_2005_Neurosci_136_563 |
| PubMedID: 16198489 |
| Title : Effects of antiepileptic drugs on attention as assessed by a five-choice serial reaction time task in rats - Shannon_2005_Epilepsy.Behav_7_620 |
| Author(s) : Shannon HE , Love PL |
| Ref : Epilepsy Behav , 7 :620 , 2005 |
| Abstract : Shannon_2005_Epilepsy.Behav_7_620 |
| ESTHER : Shannon_2005_Epilepsy.Behav_7_620 |
| PubMedSearch : Shannon_2005_Epilepsy.Behav_7_620 |
| PubMedID: 16253568 |
| Title : Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats - Jones_2005_J.Pharmacol.Exp.Ther_312_1055 |
| Author(s) : Jones CK , Eberle EL , Shaw DB , McKinzie DL , Shannon HE |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 312 :1055 , 2005 |
| Abstract : Jones_2005_J.Pharmacol.Exp.Ther_312_1055 |
| ESTHER : Jones_2005_J.Pharmacol.Exp.Ther_312_1055 |
| PubMedSearch : Jones_2005_J.Pharmacol.Exp.Ther_312_1055 |
| PubMedID: 15574685 |
| Title : Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in rats - Shannon_2004_Epilepsy.Behav_5_857 |
| Author(s) : Shannon HE , Love PL |
| Ref : Epilepsy Behav , 5 :857 , 2004 |
| Abstract : Shannon_2004_Epilepsy.Behav_5_857 |
| ESTHER : Shannon_2004_Epilepsy.Behav_5_857 |
| PubMedSearch : Shannon_2004_Epilepsy.Behav_5_857 |
| PubMedID: 15582833 |
| Title : Within-session repeated acquisition behavior in rats as a potential model of executive function - Shannon_2004_Eur.J.Pharmacol_498_125 |
| Author(s) : Shannon HE , Love PL |
| Ref : European Journal of Pharmacology , 498 :125 , 2004 |
| Abstract : Shannon_2004_Eur.J.Pharmacol_498_125 |
| ESTHER : Shannon_2004_Eur.J.Pharmacol_498_125 |
| PubMedSearch : Shannon_2004_Eur.J.Pharmacol_498_125 |
| PubMedID: 15363986 |
| Title : Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models - Shannon_2004_Epilepsy.Res_61_49 |
| Author(s) : Shannon HE , Yang L |
| Ref : Epilepsy Research , 61 :49 , 2004 |
| Abstract : Shannon_2004_Epilepsy.Res_61_49 |
| ESTHER : Shannon_2004_Epilepsy.Res_61_49 |
| PubMedSearch : Shannon_2004_Epilepsy.Res_61_49 |
| PubMedID: 15451008 |
| Title : Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice - Bymaster_2001_Life.Sci_68(22-23)_2473 |
| Author(s) : Bymaster FP , Carter PA , Zhang L , Falcone JF , Stengel PW , Cohen ML , Shannon HE , Gomeza J , Wess J , Felder CC |
| Ref : Life Sciences , 68 :2473 , 2001 |
| Abstract : Bymaster_2001_Life.Sci_68(22-23)_2473 |
| ESTHER : Bymaster_2001_Life.Sci_68(22-23)_2473 |
| PubMedSearch : Bymaster_2001_Life.Sci_68(22-23)_2473 |
| PubMedID: 11392615 |
| Title : The muscarinic agonist xanomeline increases monoamine release and immediate early gene expression in the rat prefrontal cortex - Perry_2001_Biol.Psychiatry_49_716 |
| Author(s) : Perry KW , Nisenbaum LK , George CA , Shannon HE , Felder CC , Bymaster FP |
| Ref : Biological Psychiatry , 49 :716 , 2001 |
| Abstract : Perry_2001_Biol.Psychiatry_49_716 |
| ESTHER : Perry_2001_Biol.Psychiatry_49_716 |
| PubMedSearch : Perry_2001_Biol.Psychiatry_49_716 |
| PubMedID: 11313039 |
| Title : Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice - Gomeza_2001_Life.Sci_68(22-23)_2457 |
| Author(s) : Gomeza J , Zhang L , Kostenis E , Felder CC , Bymaster FP , Brodkin J , Shannon HE , Xia B , Duttaroy A , Deng CX , Wess J |
| Ref : Life Sciences , 68 :2457 , 2001 |
| Abstract : Gomeza_2001_Life.Sci_68(22-23)_2457 |
| ESTHER : Gomeza_2001_Life.Sci_68(22-23)_2457 |
| PubMedSearch : Gomeza_2001_Life.Sci_68(22-23)_2457 |
| PubMedID: 11392613 |
| Title : Antihyperalgesic effects of the muscarinic receptor ligand vedaclidine in models involving central sensitization in rats - Shannon_2001_Pain_93_221 |
| Author(s) : Shannon HE , Jones CK , Li DL , Peters SC , Simmons RM , Iyengar S |
| Ref : Pain , 93 :221 , 2001 |
| Abstract : Shannon_2001_Pain_93_221 |
| ESTHER : Shannon_2001_Pain_93_221 |
| PubMedSearch : Shannon_2001_Pain_93_221 |
| PubMedID: 11514081 |
| Title : The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance - Rasmussen_2001_Schizophr.Res_49_193 |
| Author(s) : Rasmussen T , Fink-Jensen A , Sauerberg P , Swedberg MD , Thomsen C , Sheardown MJ , Jeppesen L , Calligaro DO , DeLapp NW , Whitesitt CA , Ward JS , Shannon HE , Bymaster FP |
| Ref : Schizophr Res , 49 :193 , 2001 |
| Abstract : Rasmussen_2001_Schizophr.Res_49_193 |
| ESTHER : Rasmussen_2001_Schizophr.Res_49_193 |
| PubMedSearch : Rasmussen_2001_Schizophr.Res_49_193 |
| PubMedID: 11343877 |
| Title : Xanomeline, an M(1)\/M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice - Shannon_2000_Schizophr.Res_42_249 |
| Author(s) : Shannon HE , Rasmussen K , Bymaster FP , Hart JC , Peters SC , Swedberg MD , Jeppesen L , Sheardown MJ , Sauerberg P , Fink-Jensen A |
| Ref : Schizophr Res , 42 :249 , 2000 |
| Abstract : Shannon_2000_Schizophr.Res_42_249 |
| ESTHER : Shannon_2000_Schizophr.Res_42_249 |
| PubMedSearch : Shannon_2000_Schizophr.Res_42_249 |
| PubMedID: 10785583 |
| Title : Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice - Rasmussen_2000_Eur.J.Pharmacol_402_241 |
| Author(s) : Rasmussen T , Sauerberg P , Nielsen EB , Swedberg MD , Thomsen C , Sheardown MJ , Jeppesen L , Calligaro DO , DeLapp NW , Whitesitt CA , Ward JS , Shannon HE , Bymaster FP , Fink-Jensen A |
| Ref : European Journal of Pharmacology , 402 :241 , 2000 |
| Abstract : Rasmussen_2000_Eur.J.Pharmacol_402_241 |
| ESTHER : Rasmussen_2000_Eur.J.Pharmacol_402_241 |
| PubMedSearch : Rasmussen_2000_Eur.J.Pharmacol_402_241 |
| PubMedID: 10958890 |
| Title : Effects of scopolamine in comparison with apomorphine and phencyclidine on prepulse inhibition in rats - Jones_2000_Eur.J.Pharmacol_391_105 |
| Author(s) : Jones CK , Shannon HE |
| Ref : European Journal of Pharmacology , 391 :105 , 2000 |
| Abstract : Jones_2000_Eur.J.Pharmacol_391_105 |
| ESTHER : Jones_2000_Eur.J.Pharmacol_391_105 |
| PubMedSearch : Jones_2000_Eur.J.Pharmacol_391_105 |
| PubMedID: 10720641 |
| Title : Reversal of pertussis toxin-induced thermal allodynia by muscarinic cholinergic agonists in mice - Womer_2000_Neuropharmacol_39_2499 |
| Author(s) : Womer DE , Shannon HE |
| Ref : Neuropharmacology , 39 :2499 , 2000 |
| Abstract : Womer_2000_Neuropharmacol_39_2499 |
| ESTHER : Womer_2000_Neuropharmacol_39_2499 |
| PubMedSearch : Womer_2000_Neuropharmacol_39_2499 |
| PubMedID: 10974334 |
| Title : Muscarinic cholinergic modulation of prepulse inhibition of the acoustic startle reflex - Jones_2000_J.Pharmacol.Exp.Ther_294_1017 |
| Author(s) : Jones CK , Shannon HE |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 294 :1017 , 2000 |
| Abstract : Jones_2000_J.Pharmacol.Exp.Ther_294_1017 |
| ESTHER : Jones_2000_J.Pharmacol.Exp.Ther_294_1017 |
| PubMedSearch : Jones_2000_J.Pharmacol.Exp.Ther_294_1017 |
| PubMedID: 10945854 |
| Title : Poster: Muscarinic receptor characterization and neurochemical effects of the antipsychotic-like muscarinic agonist PTAC - |
| Author(s) : Bymaster FP , Shannon HE , DeLapp NW , Calligaro DO , Perry KW , Zhang W , Rasmussen K , Ward JS , Fink-Jensen A , Olesen PH , Rasmussen T , Sheardown M , Swedberg MD , Jeppesen L , Sauerberg P |
| Ref : Life Sciences , 64 :579 , 1999 |
| PubMedID: |
| Title : Direct pharmacological comparison of the muscarinic receptors mediating relaxation and contraction in the rabbit thoracic aorta - Sawyer_1999_Gen.Pharmacol_32_445 |
| Author(s) : Sawyer BD , Bymaster FP , Calligaro DO , Falcone J , Mitch CH , Ward JS , Whitesitt CA , Shannon HE |
| Ref : General Pharmacology , 32 :445 , 1999 |
| Abstract : Sawyer_1999_Gen.Pharmacol_32_445 |
| ESTHER : Sawyer_1999_Gen.Pharmacol_32_445 |
| PubMedSearch : Sawyer_1999_Gen.Pharmacol_32_445 |
| PubMedID: 10323485 |
| Title : Poster: Behavioral and electrophysiological effects of the antipsychotic-like muscarinic agonist PTAC - |
| Author(s) : Shannon HE , Bymaster FP , Rasmussen K , DeLapp NW , Calligaro DO , Perry KW , Mitch CH , Ward JS , Fink-Jensen A , Olesen PH , Rasmussen T , Sheardown M , Swedberg MD , Jeppesen L , Sauerberg P |
| Ref : Life Sciences , 64 :587 , 1999 |
| PubMedID: |
| Title : Potential role of muscarinic receptors in schizophrenia - Bymaster_1999_Life.Sci_64(6-7)_527 |
| Author(s) : Bymaster FP , Shannon HE , Rasmussen K , DeLapp NW , Ward JS , Calligaro DO , Mitch CH , Whitesitt CA , Ludvigsen TS , Sheardown MJ , Swedberg MD , Rasmussen T , Olesen PH , Jeppesen L , Sauerberg P , Fink-Jensen A |
| Ref : Life Sciences , 64 :527 , 1999 |
| Abstract : Bymaster_1999_Life.Sci_64(6-7)_527 |
| ESTHER : Bymaster_1999_Life.Sci_64(6-7)_527 |
| PubMedSearch : Bymaster_1999_Life.Sci_64(6-7)_527 |
| PubMedID: 10069519 |
| Title : Poster: Determination of the intrinsic functional muscarinic activity of xanomeline - |
| Author(s) : Falcone JF , Bymaster FP , Butler T , Thomsen C , Calligaro DO , Shannon HE , Whitesitt C , Ward J , Sheardown M , Fink-Jensen A , Jeppesen L , Sauerberg P , DeLapp NC |
| Ref : Life Sciences , 64 :579 , 1999 |
| PubMedID: |
| Title : Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats - Shannon_1999_J.Pharmacol.Exp.Ther_290_901 |
| Author(s) : Shannon HE , Hart JC , Bymaster FP , Calligaro DO , DeLapp NW , Mitch CH , Ward JS , Fink-Jensen A , Sauerberg P , Jeppesen L , Sheardown MJ , Swedberg MD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 290 :901 , 1999 |
| Abstract : Shannon_1999_J.Pharmacol.Exp.Ther_290_901 |
| ESTHER : Shannon_1999_J.Pharmacol.Exp.Ther_290_901 |
| PubMedSearch : Shannon_1999_J.Pharmacol.Exp.Ther_290_901 |
| PubMedID: 10411607 |
| Title : Poster: Muscarinic agonists with antipsychotic-like activity. Structure activity-relationships of 1,2,5-thiadiazole analogues with functioally dopamine antagonist activity - |
| Author(s) : Sauerberg P , Jeppesen L , Olesen PH , Rasmussen T , Swedberg MD , Sheardown MJ , Fink-Jensen A , Thomsen C , Thogersen H , Ward JS , Calligaro DO , DeLapp NW , Bymaster FP , Shannon HE |
| Ref : Life Sciences , 64 :555 , 1999 |
| PubMedID: |
| Title : 1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.0(2,6)]heptanes as new potent muscarinic M1 agonists: structure-activity relationship for 3-aryl-2-propyn-1-yloxy and 3-aryl-2-propyn-1-ylthio derivatives - Jeppesen_1999_J.Med.Chem_42_1999 |
| Author(s) : Jeppesen L , Olesen PH , Hansen L , Sheardown MJ , Thomsen C , Rasmussen T , Jensen AF , Christensen MS , Rimvall K , Ward JS , Whitesitt CA , Calligaro DO , Bymaster FP , DeLapp NW , Felder CC , Shannon HE , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 42 :1999 , 1999 |
| Abstract : Jeppesen_1999_J.Med.Chem_42_1999 |
| ESTHER : Jeppesen_1999_J.Med.Chem_42_1999 |
| PubMedSearch : Jeppesen_1999_J.Med.Chem_42_1999 |
| PubMedID: 10354408 |
| Title : Poster: New potent muscarinic 1,2,5-thiadiazole-azacycles and dimers hereof - |
| Author(s) : Jeppesen L , Sauerberg P , Olesen PH , Sheardown MJ , Thomsen C , Rasmussen T , Fink-Jensen A , Christensen MS , Ward JS , Whitesitt C , Calligaro DO , Bymaster FP , DeLapp NW , Felder CC , Shannon HE |
| Ref : Life Sciences , 64 :555 , 1999 |
| PubMedID: |
| Title : Poster: Reversal of pertussis toxin-induced thermal allodynia by muscarinic cholinergic agonists in mice - |
| Author(s) : Zhang L , Shannon HE , Bymaster FP , DeLapp NW , Womer DE , Mitch CH , Ward JS , Olesen PH , Sheardown M , Swedberg MD , Jeppesen L , Sauerberg P |
| Ref : Life Sciences , 64 :587 , 1999 |
| PubMedID: |
| Title : Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats - Fink-Jensen_1998_Neuroreport_9_3481 |
| Author(s) : Fink-Jensen A , Kristensen P , Shannon HE , Calligaro DO , DeLapp NW , Whitesitt CA , Ward JS , Thomsen C , Rasmusseen T , Sheardown MJ , Jeppesen L , Sauerberg P , Bymaster FP |
| Ref : Neuroreport , 9 :3481 , 1998 |
| Abstract : Fink-Jensen_1998_Neuroreport_9_3481 |
| ESTHER : Fink-Jensen_1998_Neuroreport_9_3481 |
| PubMedSearch : Fink-Jensen_1998_Neuroreport_9_3481 |
| PubMedID: 9855303 |
| Title : Muscarinic agonists with antipsychotic-like activity: structure-activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity - Sauerberg_1998_J.Med.Chem_41_4378 |
| Author(s) : Sauerberg P , Jeppesen L , Olesen PH , Rasmussen T , Swedberg MD , Sheardown MJ , Fink-Jensen A , Thomsen C , Thogersen H , Rimvall K , Ward JS , Calligaro DO , DeLapp NW , Bymaster FP , Shannon HE |
| Ref : Journal of Medicinal Chemistry , 41 :4378 , 1998 |
| Abstract : Sauerberg_1998_J.Med.Chem_41_4378 |
| ESTHER : Sauerberg_1998_J.Med.Chem_41_4378 |
| PubMedSearch : Sauerberg_1998_J.Med.Chem_41_4378 |
| PubMedID: 9784113 |
| Title : Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic m1 receptor activation - Sauerberg_1998_Bioorg.Med.Chem.Lett_8_2897 |
| Author(s) : Sauerberg P , Jeppesen L , Olesen PH , Sheardown MJ , Fink-Jensen A , Rasmussen T , Rimvall K , Shannon HE , Bymaster FP , DeLapp NW , Calligaro DO , Ward JS , Whitesitt CA , Thomsen C |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :2897 , 1998 |
| Abstract : Sauerberg_1998_Bioorg.Med.Chem.Lett_8_2897 |
| ESTHER : Sauerberg_1998_Bioorg.Med.Chem.Lett_8_2897 |
| PubMedSearch : Sauerberg_1998_Bioorg.Med.Chem.Lett_8_2897 |
| PubMedID: 9873644 |
| Title : Conformationally constrained analogues of the muscarinic agonist 3-(4-(methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyr idine. Synthesis, receptor affinity, and antinociceptive activity - Sauerberg_1998_J.Med.Chem_41_109 |
| Author(s) : Sauerberg P , Olesen PH , Sheardown MJ , Rimvall K , Thogersen H , Shannon HE , Sawyer BD , Ward JS , Bymaster FP , DeLapp NW , Calligaro DO , Swedberg MD |
| Ref : Journal of Medicinal Chemistry , 41 :109 , 1998 |
| Abstract : Sauerberg_1998_J.Med.Chem_41_109 |
| ESTHER : Sauerberg_1998_J.Med.Chem_41_109 |
| PubMedSearch : Sauerberg_1998_J.Med.Chem_41_109 |
| PubMedID: 9438027 |
| Title : Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects - Bymaster_1998_Brain.Res_795_179 |
| Author(s) : Bymaster FP , Carter PA , Peters SC , Zhang W , Ward JS , Mitch CH , Calligaro DO , Whitesitt CA , DeLapp NC , Shannon HE , Rimvall K , Jeppesen L , Sheardown MJ , Fink-Jensen A , Sauerberg P |
| Ref : Brain Research , 795 :179 , 1998 |
| Abstract : Bymaster_1998_Brain.Res_795_179 |
| ESTHER : Bymaster_1998_Brain.Res_795_179 |
| PubMedSearch : Bymaster_1998_Brain.Res_795_179 |
| PubMedID: 9622623 |
| Title : 1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists - Ward_1998_J.Med.Chem_41_379 |
| Author(s) : Ward JS , Merritt L , Calligaro DO , Bymaster FP , Shannon HE , Mitch CH , Whitesitt CA , Brunsting D , Sheardown MJ , Olesen PH , Swedberg MD , Jeppesen L , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 41 :379 , 1998 |
| Abstract : Ward_1998_J.Med.Chem_41_379 |
| ESTHER : Ward_1998_J.Med.Chem_41_379 |
| PubMedSearch : Ward_1998_J.Med.Chem_41_379 |
| PubMedID: 9464368 |
| Title : Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane - Bymaster_1998_Eur.J.Pharmacol_356_109 |
| Author(s) : Bymaster FP , Shannon HE , Rasmussen K , DeLapp NW , Mitch CH , Ward JS , Calligaro DO , Ludvigsen TS , Sheardown MJ , Olesen PH , Swedberg MD , Sauerberg P , Fink-Jensen A |
| Ref : European Journal of Pharmacology , 356 :109 , 1998 |
| Abstract : Bymaster_1998_Eur.J.Pharmacol_356_109 |
| ESTHER : Bymaster_1998_Eur.J.Pharmacol_356_109 |
| PubMedSearch : Bymaster_1998_Eur.J.Pharmacol_356_109 |
| PubMedID: 9774240 |
| Title : Butylthio[2.2.2] (NNC 11-1053\/LY297802): an orally active muscarinic agonist analgesic - Swedberg_1997_J.Pharmacol.Exp.Ther_281_876 |
| Author(s) : Swedberg MD , Sheardown MJ , Sauerberg P , Olesen PH , Suzdak PD , Hansen KT , Bymaster FP , Ward JS , Mitch CH , Calligaro DO , DeLapp NW , Shannon HE |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 281 :876 , 1997 |
| Abstract : Swedberg_1997_J.Pharmacol.Exp.Ther_281_876 |
| ESTHER : Swedberg_1997_J.Pharmacol.Exp.Ther_281_876 |
| PubMedSearch : Swedberg_1997_J.Pharmacol.Exp.Ther_281_876 |
| PubMedID: 9152397 |
| Title : Poster: Conformationally constrained analogs of the muscarinic agonist methylthio-TZTP. Synthesis, receptor affinity and analgesic activity - |
| Author(s) : Sauerberg P , Olesen PH , Thogersen H , Nielsen S , Sheardown MJ , Rimvall K , Shannon HE , Ward JS , Mitch CH , Bymaster FP , Swedberg MD |
| Ref : Life Sciences , 60 :1164 , 1997 |
| PubMedID: |
| Title : Poster: Stimulation of phosphoinositide hydrolysis in vivo by xanomeline and other muscarinic agents - |
| Author(s) : Bymaster FP , Carter PA , Shannon HE , DeLapp NC , Whitesitt CA , Ward JS , Calligaro DO , Mitch CH , Sheardown MJ , Swedberg MD , Rimvall K , Fink-Jensen A , Jeppesen L , Sauerberg P |
| Ref : Life Sciences , 60 :1165 , 1997 |
| PubMedID: |
| Title : Poster: The tetrahydropyridine ring confers optimal M-1 selectivity and blood brain barrier penetration among hexyloxy-1,2,5-thiadiazole azacycles - |
| Author(s) : Ward JS , Merritt L , Stratford R , Brown TJ , Wijayaratne R , Szewczyk SP , Calligaro DO , Bymaster FP , Shannon HE , Mitch CH , Johnson DW , Wikel JH , Olesen PH , Sheardown MJ , Swedberg MD , Sauerberg P |
| Ref : Life Sciences , 60 :1165 , 1997 |
| PubMedID: |
| Title : Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice - Gleason_1997_Psychopharmacology.(Berl)_129_79 |
| Author(s) : Gleason SD , Shannon HE |
| Ref : Psychopharmacology (Berl) , 129 :79 , 1997 |
| Abstract : Gleason_1997_Psychopharmacology.(Berl)_129_79 |
| ESTHER : Gleason_1997_Psychopharmacology.(Berl)_129_79 |
| PubMedSearch : Gleason_1997_Psychopharmacology.(Berl)_129_79 |
| PubMedID: 9122367 |
| Title : Muscarinic analgesics with potent and selective effects on the gastrointestinal tract: potential application for the treatment of irritable bowel syndrome - Mitch_1997_J.Med.Chem_40_538 |
| Author(s) : Mitch CH , Brown TJ , Bymaster FP , Calligaro DO , Dieckman D , Merrit L , Peters SC , Quimby SJ , Shannon HE , Shipley LA , Ward JS , Hansen K , Olesen PH , Sauerberg P , Sheardown MJ , Swedberg MD , Suzdak P , Greenwood B |
| Ref : Journal of Medicinal Chemistry , 40 :538 , 1997 |
| Abstract : Mitch_1997_J.Med.Chem_40_538 |
| ESTHER : Mitch_1997_J.Med.Chem_40_538 |
| PubMedSearch : Mitch_1997_J.Med.Chem_40_538 |
| PubMedID: 9046345 |
| Title : Poster: An immunoblot assay for PTX ADP-ribosylation of brain and spinal cord Gi\/0 proteins - |
| Author(s) : DeLapp NW , Womer DE , Shannon HE |
| Ref : Life Sciences , 60 :1179 , 1997 |
| PubMedID: |
| Title : Pharmacology of butylthio[2.2.2] (LY297802\/NNC11-1053): a novel analgesic with mixed muscarinic receptor agonist and antagonist activity - Shannon_1997_J.Pharmacol.Exp.Ther_281_884 |
| Author(s) : Shannon HE , Sheardown MJ , Bymaster FP , Calligaro DO , DeLapp NW , Gidda J , Mitch CH , Sawyer BD , Stengel PW , Ward JS , Wong DT , Olesen PH , Suzdak PD , Sauerberg P , Swedberg MD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 281 :884 , 1997 |
| Abstract : Shannon_1997_J.Pharmacol.Exp.Ther_281_884 |
| ESTHER : Shannon_1997_J.Pharmacol.Exp.Ther_281_884 |
| PubMedSearch : Shannon_1997_J.Pharmacol.Exp.Ther_281_884 |
| PubMedID: 9152398 |
| Title : In vivo pharmacology of butylthio[2.2.2] (LY297802 \/ NNC11-1053), an orally acting antinociceptive muscarinic agonist - Shannon_1997_Life.Sci_60(13-14)_969 |
| Author(s) : Shannon HE , Womer DE , Bymaster FP , Calligaro DO , DeLapp NC , Mitch CH , Ward JS , Whitesitt CA , Swedberg MD , Sheardown MJ , Fink-Jensen A , Olesen PH , Rimvall K , Sauerberg P |
| Ref : Life Sciences , 60 :969 , 1997 |
| Abstract : Shannon_1997_Life.Sci_60(13-14)_969 |
| ESTHER : Shannon_1997_Life.Sci_60(13-14)_969 |
| PubMedSearch : Shannon_1997_Life.Sci_60(13-14)_969 |
| PubMedID: 9121363 |
| Title : Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease - Bodick_1997_Arch.Neurol_54_465 |
| Author(s) : Bodick NC , Offen WW , Levey AI , Cutler NR , Gauthier SG , Satlin A , Shannon HE , Tollefson GD , Rasmussen K , Bymaster FP , Hurley DJ , Potter WZ , Paul SM |
| Ref : Archives of Neurology , 54 :465 , 1997 |
| Abstract : Bodick_1997_Arch.Neurol_54_465 |
| ESTHER : Bodick_1997_Arch.Neurol_54_465 |
| PubMedSearch : Bodick_1997_Arch.Neurol_54_465 |
| PubMedID: 9109749 |
| Title : The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease - Bodick_1997_Alzheimer.Dis.Assoc.Disord_11 Suppl 4_S16 |
| Author(s) : Bodick NC , Offen WW , Shannon HE , Satterwhite J , Lucas R , van Lier R , Paul SM |
| Ref : Alzheimer Disease & Associated Disorders , 11 Suppl 4 :S16 , 1997 |
| Abstract : Bodick_1997_Alzheimer.Dis.Assoc.Disord_11 Suppl 4_S16 |
| ESTHER : Bodick_1997_Alzheimer.Dis.Assoc.Disord_11 Suppl 4_S16 |
| PubMedSearch : Bodick_1997_Alzheimer.Dis.Assoc.Disord_11 Suppl 4_S16 |
| PubMedID: 9339268 |
| Title : M1 receptor agonist activity is not a requirement for muscarinic antinociception - Sheardown_1997_J.Pharmacol.Exp.Ther_281_868 |
| Author(s) : Sheardown MJ , Shannon HE , Swedberg MD , Suzdak PD , Bymaster FP , Olesen PH , Mitch CH , Ward JS , Sauerberg P |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 281 :868 , 1997 |
| Abstract : Sheardown_1997_J.Pharmacol.Exp.Ther_281_868 |
| ESTHER : Sheardown_1997_J.Pharmacol.Exp.Ther_281_868 |
| PubMedSearch : Sheardown_1997_J.Pharmacol.Exp.Ther_281_868 |
| PubMedID: 9152396 |
| Title : Detrusor regeneration in the rat using porcine small intestinal submucosal grafts: functional innervation and receptor expression - Vaught_1996_J.Urol_155_374 |
| Author(s) : Vaught JD , Kropp BP , Sawyer BD , Rippy MK , Badylak SF , Shannon HE , Thor KB |
| Ref : J Urol , 155 :374 , 1996 |
| Abstract : Vaught_1996_J.Urol_155_374 |
| ESTHER : Vaught_1996_J.Urol_155_374 |
| PubMedSearch : Vaught_1996_J.Urol_155_374 |
| PubMedID: 7490890 |
| Title : Muscarinic agonist inhibition of rat striatal adenylate cyclase is enhanced by dopamine stimulation - DeLapp_1996_Life.Sci_59_565 |
| Author(s) : DeLapp NW , Eckols K , Shannon HE |
| Ref : Life Sciences , 59 :565 , 1996 |
| Abstract : DeLapp_1996_Life.Sci_59_565 |
| ESTHER : DeLapp_1996_Life.Sci_59_565 |
| PubMedSearch : DeLapp_1996_Life.Sci_59_565 |
| PubMedID: 8761345 |
| Title : PET study of the M1-agonists [11C]xanomeline and [11C]butylthio-TZTP in monkey and man - Farde_1996_Dementia_7_187 |
| Author(s) : Farde L , Suhara T , Halldin C , Nyback H , Nakashima Y , Swahn CG , Karlsson P , Ginovart N , Bymaster FP , Shannon HE , Foged C , Suzdak PD , Sauerberg P |
| Ref : Dementia , 7 :187 , 1996 |
| Abstract : Farde_1996_Dementia_7_187 |
| ESTHER : Farde_1996_Dementia_7_187 |
| PubMedSearch : Farde_1996_Dementia_7_187 |
| PubMedID: 8835881 |
| Title : Poster: The M1 agonist xanomeline potently stimulates APPs release from CHO-m1 cells - |
| Author(s) : DeLapp NW , Eckols K , Bymaster FP , Mitch CH , Shannon HE , Ward JS |
| Ref : Life Sciences , 56(11-12) :1024 , 1995 |
| PubMedID: |
| Title : Muscarinic agonists as analgesics. Antinociceptive activity versus M1 activity: SAR of alkylthio-TZTP's and related 1,2,5-thiadiazole analogs - Sauerberg_1995_Life.Sci_56(11-12)_807 |
| Author(s) : Sauerberg P , Olesen PH , Sheardown MJ , Suzdak PD , Shannon HE , Bymaster FP , Calligaro DO , Mitch CH , Ward JS , Swedberg MD |
| Ref : Life Sciences , 56(11-12) :807 , 1995 |
| Abstract : Sauerberg_1995_Life.Sci_56(11-12)_807 |
| ESTHER : Sauerberg_1995_Life.Sci_56(11-12)_807 |
| PubMedSearch : Sauerberg_1995_Life.Sci_56(11-12)_807 |
| PubMedID: 10188779 |
| Title : Novel alkoxy-oxazolyl-tetrahydropyridine muscarinic cholinergic receptor antagonists - Shannon_1995_Psychopharmacology.(Berl)_117_208 |
| Author(s) : Shannon HE , Bymaster FP , Hendrix JC , Quimby SJ , Mitch CH |
| Ref : Psychopharmacology (Berl) , 117 :208 , 1995 |
| Abstract : Shannon_1995_Psychopharmacology.(Berl)_117_208 |
| ESTHER : Shannon_1995_Psychopharmacology.(Berl)_117_208 |
| PubMedSearch : Shannon_1995_Psychopharmacology.(Berl)_117_208 |
| PubMedID: 7753969 |
| Title : Poster: 3-(3-Hexyloxypyrazinyl)quinuclidine as a functionally selective M1 agonist - |
| Author(s) : Ward JS , Merritt L , Calligaro DO , Bymaster FP , Shannon HE , Sawyer BD , Mitch CH , Sheardown MJ , Olesen PH , Suzdak PD , Swedberg MD , Sauerberg P |
| Ref : Life Sciences , 56(11-12) :1003 , 1995 |
| PubMedID: |
| Title : Poster: Sidechain steric bulk and muscarinic agonist sar in alkoxy-TZTP's - |
| Author(s) : Mitch CH , Bymaster FP , Calligaro DO , Quimby SJ , Sawyer BD , Ward JS , Olesen PH , Sauerberg P , Sheardown MJ , Suzdak PD , Swedberg MD , Shannon HE |
| Ref : Life Sciences , 56(11-12) :1004 , 1995 |
| PubMedID: |
| Title : Poster: Muscarinic receptor characterization and evaluation of a series of novel muscarinic ligands in the isolated rabbit thoracic aorta - |
| Author(s) : Sawyer BD , Shannon HE , Ward JS , Mitch CH , Sheardown MJ , Olesen PH , Sauerberg P |
| Ref : Life Sciences , 56(11-12) :1004 , 1995 |
| PubMedID: |
| Title : Functionally selective M1 muscarinic agonists. 3. Side chains and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles - Ward_1995_J.Med.Chem_38_3469 |
| Author(s) : Ward JS , Merritt L , Calligaro DO , Bymaster FP , Shannon HE , Sawyer BD , Mitch CH , Deeter JB , Peters SC , Sheardown MJ , Olesen PH , Swedberg MD , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 38 :3469 , 1995 |
| Abstract : Ward_1995_J.Med.Chem_38_3469 |
| ESTHER : Ward_1995_J.Med.Chem_38_3469 |
| PubMedSearch : Ward_1995_J.Med.Chem_38_3469 |
| PubMedID: 7658434 |
| Title : The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells - Eckols_1995_Life.Sci_57_1183 |
| Author(s) : Eckols K , Bymaster FP , Mitch CH , Shannon HE , Ward JS , DeLapp NW |
| Ref : Life Sciences , 57 :1183 , 1995 |
| Abstract : Eckols_1995_Life.Sci_57_1183 |
| ESTHER : Eckols_1995_Life.Sci_57_1183 |
| PubMedSearch : Eckols_1995_Life.Sci_57_1183 |
| PubMedID: 7674807 |
| Title : Poster: Arachidonic acid release by muscarinic agents in cell lines transfected with muscarinic receptors - |
| Author(s) : Bymaster FP , Falcone JF , Shannon HE , Calligaro DO |
| Ref : Life Sciences , 56(11-12) :1016 , 1995 |
| PubMedID: |
| Title : Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708\/NNC11-0232) - Bymaster_1994_J.Pharmacol.Exp.Ther_269_282 |
| Author(s) : Bymaster FP , Wong DT , Mitch CH , Ward JS , Calligaro DO , Schoepp DD , Shannon HE , Sheardown MJ , Olesen PH , Suzdak PD , Swedberg MD , Sauerberg P , et al. |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 269 :282 , 1994 |
| Abstract : Bymaster_1994_J.Pharmacol.Exp.Ther_269_282 |
| ESTHER : Bymaster_1994_J.Pharmacol.Exp.Ther_269_282 |
| PubMedSearch : Bymaster_1994_J.Pharmacol.Exp.Ther_269_282 |
| PubMedID: 7909558 |
| Title : Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors - Shannon_1994_J.Pharmacol.Exp.Ther_269_271 |
| Author(s) : Shannon HE , Bymaster FP , Calligaro DO , Greenwood B , Mitch CH , Sawyer BD , Ward JS , Wong DT , Olesen PH , Sheardown MJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 269 :271 , 1994 |
| Abstract : Shannon_1994_J.Pharmacol.Exp.Ther_269_271 |
| ESTHER : Shannon_1994_J.Pharmacol.Exp.Ther_269_271 |
| PubMedSearch : Shannon_1994_J.Pharmacol.Exp.Ther_269_271 |
| PubMedID: 7909557 |
| Title : Poster: Alkoxy sar around the functionally M1 selective agonist hexyloxy-TZTP - |
| Author(s) : Sauerberg P , Olesen PH , Sheardown MJ , Suzdak PD , Swedberg MD , Mitch CH , Ward JS , Calligaro DO , Sawyer BD , Bymaster FP , Shannon HE |
| Ref : Life Sciences , 52(5-6) :549 , 1993 |
| PubMedID: |
| Title : Poster: Muscarinic analgesia is mediated by non-M1 muscarinic receptors - |
| Author(s) : Swedberg MD , Sheardown MJ , Sauerberg P , Olesen PH , Suzdak PD , Shannon HE , Bymaster FP , Ward JS , Mitch CH , Calligaro DO |
| Ref : Life Sciences , 52(5-6) :594 , 1993 |
| PubMedID: |
| Title : Comparative behavioral and neurochemical activities of cholinergic antagonists in rats - Bymaster_1993_J.Pharmacol.Exp.Ther_267_16 |
| Author(s) : Bymaster FP , Heath I , Hendrix JC , Shannon HE |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 267 :16 , 1993 |
| Abstract : Bymaster_1993_J.Pharmacol.Exp.Ther_267_16 |
| ESTHER : Bymaster_1993_J.Pharmacol.Exp.Ther_267_16 |
| PubMedSearch : Bymaster_1993_J.Pharmacol.Exp.Ther_267_16 |
| PubMedID: 7901390 |
| Title : Poster: Synthesis and structure-activity relationship of 3-(pyrazinyl)- 1, 2, 5, 6-tetrahydro-1-methylpyridines. Construction of a molecular model for the M-1 pharmacophore - |
| Author(s) : Ward JS , Merritt L , Klimkowski VJ , Lamb ML , Mitch CH , Bymaster FP , Sawyer BD , Shannon HE , Olesen PH , Honore T , Sheardown MJ , Sauerberg P |
| Ref : Life Sciences , 52(5-6) :549 , 1993 |
| PubMedID: |
| Title : Poster: 3-hexyloxy analogs of TZTP are potent and selective M1 agonists in brain of rat in vivo - |
| Author(s) : Bymaster FP , Wong DT , Mitch CH , Ward JS , Calligaro DO , Shannon HE , Sawyer BD , Quimby SJ , Sheardown MJ , Olesen PH , Suzdak PD , Sauerberg P |
| Ref : Life Sciences , 52(5-6) :593 , 1993 |
| PubMedID: |
| Title : Muscarinic M1 receptor agonist actions of muscarinic receptor agonists in rabbit vas deferens - Shannon_1993_Eur.J.Pharmacol_232_47 |
| Author(s) : Shannon HE , Sawyer BD , Bemis KG , Bymaster FP , Health I , Mitch CH , Ward JS |
| Ref : European Journal of Pharmacology , 232 :47 , 1993 |
| Abstract : Shannon_1993_Eur.J.Pharmacol_232_47 |
| ESTHER : Shannon_1993_Eur.J.Pharmacol_232_47 |
| PubMedSearch : Shannon_1993_Eur.J.Pharmacol_232_47 |
| PubMedID: 8458395 |
| Title : Poster: Hexyloxy-TZTP: A potent and selective M1 agonist in-vitro - |
| Author(s) : Mitch CH , Bymaster FP , Calligaro DO , Quimby SJ , Sawyer BD , Shannon HE , Ward JS , Olesen PH , Sauerberg P , Sheardown MJ , Suzdak PD |
| Ref : Life Sciences , 52(5-6) :550 , 1993 |
| PubMedID: |
| Title : Novel functional M1 selective muscarinic agonists. 2. Synthesis and structure-activity relationships of 3-pyrazinyl-1,2,5,6-tetrahydro-1-methylpyridines. Construction of a molecular model for the M1 pharmacophore - Ward_1992_J.Med.Chem_35_4011 |
| Author(s) : Ward JS , Merritt L , Klimkowski VJ , Lamb ML , Mitch CH , Bymaster FP , Sawyer BD , Shannon HE , Olesen PH , Honore T , Sheardown MJ , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 35 :4011 , 1992 |
| Abstract : Ward_1992_J.Med.Chem_35_4011 |
| ESTHER : Ward_1992_J.Med.Chem_35_4011 |
| PubMedSearch : Ward_1992_J.Med.Chem_35_4011 |
| PubMedID: 1433209 |
| Title : Interactions between scopolamine and muscarinic cholinergic agonists or cholinesterase inhibitors on spatial alternation performance in rats - Shannon_1990_J.Pharmacol.Exp.Ther_255_1071 |
| Author(s) : Shannon HE , Bemis KG , Hendrix JC , Ward JS |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 255 :1071 , 1990 |
| Abstract : Shannon_1990_J.Pharmacol.Exp.Ther_255_1071 |
| ESTHER : Shannon_1990_J.Pharmacol.Exp.Ther_255_1071 |
| PubMedSearch : Shannon_1990_J.Pharmacol.Exp.Ther_255_1071 |
| PubMedID: 2262893 |
| Title : A comparison of the effects of cholinergic and dopaminergic agents on scopolamine-induced hyperactivity in mice - Shannon_1990_J.Pharmacol.Exp.Ther_255_549 |
| Author(s) : Shannon HE , Peters SC |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 255 :549 , 1990 |
| Abstract : Shannon_1990_J.Pharmacol.Exp.Ther_255_549 |
| ESTHER : Shannon_1990_J.Pharmacol.Exp.Ther_255_549 |
| PubMedSearch : Shannon_1990_J.Pharmacol.Exp.Ther_255_549 |
| PubMedID: 2243341 |
| Title : Assessment of working memory in rats using spatial alternation behavior with variable retention intervals: effects of fixed-ratio size and scopolamine - Shannon_1990_Psychopharmacology.(Berl)_100_491 |
| Author(s) : Shannon HE , Bemis KG , Hart JC |
| Ref : Psychopharmacology (Berl) , 100 :491 , 1990 |
| Abstract : Shannon_1990_Psychopharmacology.(Berl)_100_491 |
| ESTHER : Shannon_1990_Psychopharmacology.(Berl)_100_491 |
| PubMedSearch : Shannon_1990_Psychopharmacology.(Berl)_100_491 |
| PubMedID: 2320710 |
| Title : Progress report from the NIDA Addiction Research Center (preclinical laboratory), Lexington, Kentucky - |
| Author(s) : Gorodetzky CW , Cone EJ , Goldberg SR , Herling S , Risner ME , Shannon HE , Vaupel DB |
| Ref : NIDA Res Monogr , 43 :85 , 1983 |
| PubMedID: 6135996 |
| Title : Progress report from the NIDA Addiction Research Center (Preclinical Laboratory), Lexington, Ky - |
| Author(s) : Gorodetzky CW , Cone EJ , Croughan JL , Goldberg SR , Risner ME , Shannon HE , Su TP , Yeh SY |
| Ref : NIDA Res Monogr , 41 :53 , 1982 |
| PubMedID: 6811942 |