Full name : Rosini Michela
First name : Michela
Mail : University of Bologna\; Dipartimento di Farmacia e Biotecnologie\; via Belmeloro 6\; 40126 Bologna
Zip Code :
City :
Country : Italy
Email : michela.rosini@unibo.it
Phone :
Fax :
Website :
Directory :
| Title : Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties - Basagni_2023_Eur.J.Med.Chem_261_115803 |
| Author(s) : Basagni F , Ortega JA , Bertozzi SM , Armirotti A , Summa M , Bertorelli R , Bartolini M , Mellor IR , Bedeschi M , Bottegoni G , Lembo V , Minarini A , Cavalli A , Rosini M |
| Ref : Eur Journal of Medicinal Chemistry , 261 :115803 , 2023 |
| Abstract : Basagni_2023_Eur.J.Med.Chem_261_115803 |
| ESTHER : Basagni_2023_Eur.J.Med.Chem_261_115803 |
| PubMedSearch : Basagni_2023_Eur.J.Med.Chem_261_115803 |
| PubMedID: 37734258 |
| Title : Functionalized Cannabinoid Subtype 2 Receptor Ligands: Fluorescent, PET, Photochromic and Covalent Molecular Probes - Basagni_2020_ChemMedChem_15_1374 |
| Author(s) : Basagni F , Rosini M , Decker M |
| Ref : ChemMedChem , 15 :1374 , 2020 |
| Abstract : Basagni_2020_ChemMedChem_15_1374 |
| ESTHER : Basagni_2020_ChemMedChem_15_1374 |
| PubMedSearch : Basagni_2020_ChemMedChem_15_1374 |
| PubMedID: 32578963 |
| Title : Memantine Derivatives as Multitarget Agents in Alzheimer's Disease - Marotta_2020_Molecules_25_ |
| Author(s) : Marotta G , Basagni F , Rosini M , Minarini A |
| Ref : Molecules , 25 : , 2020 |
| Abstract : Marotta_2020_Molecules_25_ |
| ESTHER : Marotta_2020_Molecules_25_ |
| PubMedSearch : Marotta_2020_Molecules_25_ |
| PubMedID: 32887400 |
| Title : Controlled Iontophoretic Delivery in Vitro and in Vivo of ARN14140-A Multitarget Compound for Alzheimer's Disease - Singhal_2019_Mol.Pharm_16_3460 |
| Author(s) : Singhal M , Merino V , Rosini M , Cavalli A , Kalia YN |
| Ref : Mol Pharm , 16 :3460 , 2019 |
| Abstract : Singhal_2019_Mol.Pharm_16_3460 |
| ESTHER : Singhal_2019_Mol.Pharm_16_3460 |
| PubMedSearch : Singhal_2019_Mol.Pharm_16_3460 |
| PubMedID: 31241959 |
| Title : Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-beta peptide in Alzheimer's disease - Rosini_2019_Eur.J.Med.Chem_180_111 |
| Author(s) : Rosini M , Simoni E , Caporaso R , Basagni F , Catanzaro M , Abu IF , Fagiani F , Fusco F , Masuzzo S , Albani D , Lanni C , Mellor IR , Minarini A |
| Ref : Eur Journal of Medicinal Chemistry , 180 :111 , 2019 |
| Abstract : Rosini_2019_Eur.J.Med.Chem_180_111 |
| ESTHER : Rosini_2019_Eur.J.Med.Chem_180_111 |
| PubMedSearch : Rosini_2019_Eur.J.Med.Chem_180_111 |
| PubMedID: 31301562 |
| Title : Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-beta aggregation - Simoni_2017_Future.Med.Chem_9_953 |
| Author(s) : Simoni E , Bartolini M , Abu IF , Blockley A , Gotti C , Bottegoni G , Caporaso R , Bergamini C , Andrisano V , Cavalli A , Mellor IR , Minarini A , Rosini M |
| Ref : Future Med Chem , 9 :953 , 2017 |
| Abstract : Simoni_2017_Future.Med.Chem_9_953 |
| ESTHER : Simoni_2017_Future.Med.Chem_9_953 |
| PubMedSearch : Simoni_2017_Future.Med.Chem_9_953 |
| PubMedID: 28632446 |
| Title : In Vivo Characterization of ARN14140, a Memantine\/Galantamine-Based Multi-Target Compound for Alzheimer's Disease - Reggiani_2016_Sci.Rep_6_33172 |
| Author(s) : Reggiani AM , Simoni E , Caporaso R , Meunier J , Keller E , Maurice T , Minarini A , Rosini M , Cavalli A |
| Ref : Sci Rep , 6 :33172 , 2016 |
| Abstract : Reggiani_2016_Sci.Rep_6_33172 |
| ESTHER : Reggiani_2016_Sci.Rep_6_33172 |
| PubMedSearch : Reggiani_2016_Sci.Rep_6_33172 |
| PubMedID: 27609215 |
| Title : Multitarget strategies in Alzheimer's disease: benefits and challenges on the road to therapeutics - Rosini_2016_Future.Med.Chem_8_697 |
| Author(s) : Rosini M , Simoni E , Caporaso R , Minarini A |
| Ref : Future Med Chem , 8 :697 , 2016 |
| Abstract : Rosini_2016_Future.Med.Chem_8_697 |
| ESTHER : Rosini_2016_Future.Med.Chem_8_697 |
| PubMedSearch : Rosini_2016_Future.Med.Chem_8_697 |
| PubMedID: 27079260 |
| Title : Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces - Rosini_2014_Neurochem.Res_39_1914 |
| Author(s) : Rosini M , Simoni E , Minarini A , Melchiorre C |
| Ref : Neurochem Res , 39 :1914 , 2014 |
| Abstract : Rosini_2014_Neurochem.Res_39_1914 |
| ESTHER : Rosini_2014_Neurochem.Res_39_1914 |
| PubMedSearch : Rosini_2014_Neurochem.Res_39_1914 |
| PubMedID: 24493627 |
| Title : The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti-Alzheimer Multitarget Profile of Dimebon - Rosini_2013_ChemMedChem_8_1276 |
| Author(s) : Rosini M , Simoni E , Bartolini M , Soriano E , Marco-Contelles J , Andrisano V , Monti B , Windisch M , Hutter-Paier B , McClymont DW , Mellor IR , Bolognesi ML |
| Ref : ChemMedChem , 8 :1276 , 2013 |
| Abstract : Rosini_2013_ChemMedChem_8_1276 |
| ESTHER : Rosini_2013_ChemMedChem_8_1276 |
| PubMedSearch : Rosini_2013_ChemMedChem_8_1276 |
| PubMedID: 23824986 |
| Title : Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment - Minarini_2012_Neuropharmacol_62_997 |
| Author(s) : Minarini A , Milelli A , Tumiatti V , Rosini M , Simoni E , Bolognesi ML , Andrisano V , Bartolini M , Motori E , Angeloni C , Hrelia S |
| Ref : Neuropharmacology , 62 :997 , 2012 |
| Abstract : Minarini_2012_Neuropharmacol_62_997 |
| ESTHER : Minarini_2012_Neuropharmacol_62_997 |
| PubMedSearch : Minarini_2012_Neuropharmacol_62_997 |
| PubMedID: 22032870 |
| Title : Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease - Simoni_2012_J.Med.Chem_55_9708 |
| Author(s) : Simoni E , Daniele S , Bottegoni G , Pizzirani D , Trincavelli ML , Goldoni L , Tarozzo G , Reggiani A , Martini C , Piomelli D , Melchiorre C , Rosini M , Cavalli A |
| Ref : Journal of Medicinal Chemistry , 55 :9708 , 2012 |
| Abstract : Simoni_2012_J.Med.Chem_55_9708 |
| ESTHER : Simoni_2012_J.Med.Chem_55_9708 |
| PubMedSearch : Simoni_2012_J.Med.Chem_55_9708 |
| PubMedID: 23033965 |
| Title : Reversible human serum albumin binding of lipocrine: a circular dichroism study - Bertucci_2011_Chirality_23_827 |
| Author(s) : Bertucci C , De Simone A , Pistolozzi M , Rosini M |
| Ref : Chirality , 23 :827 , 2011 |
| Abstract : Bertucci_2011_Chirality_23_827 |
| ESTHER : Bertucci_2011_Chirality_23_827 |
| PubMedSearch : Bertucci_2011_Chirality_23_827 |
| PubMedID: 21919078 |
| Title : Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease - Rosini_2011_Eur.J.Med.Chem_46_5435 |
| Author(s) : Rosini M , Simoni E , Bartolini M , Tarozzi A , Matera R , Milelli A , Hrelia P , Andrisano V , Bolognesi ML , Melchiorre C |
| Ref : Eur Journal of Medicinal Chemistry , 46 :5435 , 2011 |
| Abstract : Rosini_2011_Eur.J.Med.Chem_46_5435 |
| ESTHER : Rosini_2011_Eur.J.Med.Chem_46_5435 |
| PubMedSearch : Rosini_2011_Eur.J.Med.Chem_46_5435 |
| PubMedID: 21924801 |
| Title : Tacrine derivatives and Alzheimer's disease - Tumiatti_2010_Curr.Med.Chem_17_1825 |
| Author(s) : Tumiatti V , Minarini A , Bolognesi ML , Milelli A , Rosini M , Melchiorre C |
| Ref : Curr Med Chem , 17 :1825 , 2010 |
| Abstract : Tumiatti_2010_Curr.Med.Chem_17_1825 |
| ESTHER : Tumiatti_2010_Curr.Med.Chem_17_1825 |
| PubMedSearch : Tumiatti_2010_Curr.Med.Chem_17_1825 |
| PubMedID: 20345341 |
| Title : Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action - Bolognesi_2009_Bioorg.Med.Chem.Lett_19_4312 |
| Author(s) : Bolognesi ML , Bartolini M , Rosini M , Andrisano V , Melchiorre C |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4312 , 2009 |
| Abstract : Bolognesi_2009_Bioorg.Med.Chem.Lett_19_4312 |
| ESTHER : Bolognesi_2009_Bioorg.Med.Chem.Lett_19_4312 |
| PubMedSearch : Bolognesi_2009_Bioorg.Med.Chem.Lett_19_4312 |
| PubMedID: 19505825 |
| Title : MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond - Bolognesi_2009_Curr.Pharm.Des_15_601 |
| Author(s) : Bolognesi ML , Rosini M , Andrisano V , Bartolini M , Minarini A , Tumiatti V , Melchiorre C |
| Ref : Curr Pharm Des , 15 :601 , 2009 |
| Abstract : Bolognesi_2009_Curr.Pharm.Des_15_601 |
| ESTHER : Bolognesi_2009_Curr.Pharm.Des_15_601 |
| PubMedSearch : Bolognesi_2009_Curr.Pharm.Des_15_601 |
| PubMedID: 19199985 |
| Title : Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks - Bolognesi_2009_J.Med.Chem_52_7883 |
| Author(s) : Bolognesi ML , Cavalli A , Bergamini C , Fato R , Lenaz G , Rosini M , Bartolini M , Andrisano V , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 52 :7883 , 2009 |
| Abstract : Bolognesi_2009_J.Med.Chem_52_7883 |
| ESTHER : Bolognesi_2009_J.Med.Chem_52_7883 |
| PubMedSearch : Bolognesi_2009_J.Med.Chem_52_7883 |
| PubMedID: 19813747 |
| Title : Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush - Rosini_2008_J.Med.Chem_51_4381 |
| Author(s) : Rosini M , Simoni E , Bartolini M , Cavalli A , Ceccarini L , Pascu N , McClymont DW , Tarozzi A , Bolognesi ML , Minarini A , Tumiatti V , Andrisano V , Mellor IR , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 51 :4381 , 2008 |
| Abstract : Rosini_2008_J.Med.Chem_51_4381 |
| ESTHER : Rosini_2008_J.Med.Chem_51_4381 |
| PubMedSearch : Rosini_2008_J.Med.Chem_51_4381 |
| PubMedID: 18605718 |
| Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer - Tumiatti_2008_J.Med.Chem_51_7308 |
| Author(s) : Tumiatti V , Milelli A , Minarini A , Rosini M , Bolognesi ML , Micco M , Andrisano V , Bartolini M , Mancini F , Recanatini M , Cavalli A , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 51 :7308 , 2008 |
| Abstract : Tumiatti_2008_J.Med.Chem_51_7308 |
| ESTHER : Tumiatti_2008_J.Med.Chem_51_7308 |
| PubMedSearch : Tumiatti_2008_J.Med.Chem_51_7308 |
| PubMedID: 18954037 |
| Title : From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease - Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| Author(s) : Bolognesi ML , Minarini A , Rosini M , Tumiatti V , Melchiorre C |
| Ref : Mini Rev Med Chem , 8 :960 , 2008 |
| Abstract : Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| ESTHER : Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| PubMedSearch : Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| PubMedID: 18782050 |
| Title : Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease - Bolognesi_2007_J.Med.Chem_50_6446 |
| Author(s) : Bolognesi ML , Cavalli A , Valgimigli L , Bartolini M , Rosini M , Andrisano V , Recanatini M , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 50 :6446 , 2007 |
| Abstract : Bolognesi_2007_J.Med.Chem_50_6446 |
| ESTHER : Bolognesi_2007_J.Med.Chem_50_6446 |
| PubMedSearch : Bolognesi_2007_J.Med.Chem_50_6446 |
| PubMedID: 18047264 |
| Title : Rational approach to discover multipotent anti-Alzheimer drugs - Rosini_2005_J.Med.Chem_48_360 |
| Author(s) : Rosini M , Andrisano V , Bartolini M , Bolognesi ML , Hrelia P , Minarini A , Tarozzi A , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 48 :360 , 2005 |
| Abstract : Rosini_2005_J.Med.Chem_48_360 |
| ESTHER : Rosini_2005_J.Med.Chem_48_360 |
| PubMedSearch : Rosini_2005_J.Med.Chem_48_360 |
| PubMedID: 15658850 |
| Title : Heterocyclic inhibitors of AChE acylation and peripheral sites - Bolognesi_2005_Farmaco_60_465 |
| Author(s) : Bolognesi ML , Andrisano V , Bartolini M , Cavalli A , Minarini A , Recanatini M , Rosini M , Tumiatti V , Melchiorre C |
| Ref : Farmaco , 60 :465 , 2005 |
| Abstract : Bolognesi_2005_Farmaco_60_465 |
| ESTHER : Bolognesi_2005_Farmaco_60_465 |
| PubMedSearch : Bolognesi_2005_Farmaco_60_465 |
| PubMedID: 15878569 |
| Title : Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues - Bolognesi_2004_J.Med.Chem_47_5945 |
| Author(s) : Bolognesi ML , Bartolini M , Cavalli A , Andrisano V , Rosini M , Minarini A , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 47 :5945 , 2004 |
| Abstract : Bolognesi_2004_J.Med.Chem_47_5945 |
| ESTHER : Bolognesi_2004_J.Med.Chem_47_5945 |
| PubMedSearch : Bolognesi_2004_J.Med.Chem_47_5945 |
| PubMedID: 15537349 |
| Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties - Tumiatti_2004_J.Med.Chem_47_6490 |
| Author(s) : Tumiatti V , Andrisano V , Banzi R , Bartolini M , Minarini A , Rosini M , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 47 :6490 , 2004 |
| Abstract : Tumiatti_2004_J.Med.Chem_47_6490 |
| ESTHER : Tumiatti_2004_J.Med.Chem_47_6490 |
| PubMedSearch : Tumiatti_2004_J.Med.Chem_47_6490 |
| PubMedID: 15588084 |
| Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine - Tumiatti_2003_J.Med.Chem_46_954 |
| Author(s) : Tumiatti V , Rosini M , Bartolini M , Cavalli A , Marucci G , Andrisano V , Angeli P , Banzi R , Minarini A , Recanatini M , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 46 :954 , 2003 |
| Abstract : Tumiatti_2003_J.Med.Chem_46_954 |
| ESTHER : Tumiatti_2003_J.Med.Chem_46_954 |
| PubMedSearch : Tumiatti_2003_J.Med.Chem_46_954 |
| PubMedID: 12620072 |
| Title : Polymethylene tetraamine backbone as template for the development of biologically active polyamines - Melchiorre_2003_Med.Res.Rev_23_200 |
| Author(s) : Melchiorre C , Antonello A , Banzi R , Bolognesi ML , Minarini A , Rosini M , Tumiatti V |
| Ref : Med Res Rev , 23 :200 , 2003 |
| Abstract : Melchiorre_2003_Med.Res.Rev_23_200 |
| ESTHER : Melchiorre_2003_Med.Res.Rev_23_200 |
| PubMedSearch : Melchiorre_2003_Med.Res.Rev_23_200 |
| PubMedID: 12500289 |
| Title : Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure - Bolognesi_2002_J.Med.Chem_45_3286 |
| Author(s) : Bolognesi ML , Bixel MG , Marucci G , Bartolini M , Krauss M , Angeli P , Antonello A , Rosini M , Tumiatti V , Hucho F , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 45 :3286 , 2002 |
| Abstract : Bolognesi_2002_J.Med.Chem_45_3286 |
| ESTHER : Bolognesi_2002_J.Med.Chem_45_3286 |
| PubMedSearch : Bolognesi_2002_J.Med.Chem_45_3286 |
| PubMedID: 12109912 |
| Title : Hexahydrochromeno[4,3-b]pyrrole derivatives as acetylcholinesterase inhibitors - Bolognesi_2001_J.Med.Chem_44_105 |
| Author(s) : Bolognesi ML , Andrisano V , Bartolini M , Minarini A , Rosini M , Tumiatti V , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 44 :105 , 2001 |
| Abstract : Bolognesi_2001_J.Med.Chem_44_105 |
| ESTHER : Bolognesi_2001_J.Med.Chem_44_105 |
| PubMedSearch : Bolognesi_2001_J.Med.Chem_44_105 |
| PubMedID: 11141093 |
| Title : [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]-trimethylammonium (McN-A-343)-related compounds. Effect of the butynyl chain inclusion into an aromatic unit on the potency for muscarinic receptors - Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| Author(s) : Tumiatti V , Angeli P , Andrisano V , Bolognesi ML , Cavalli A , Marucci G , Minarini A , Recanatini M , Rosini M , Melchiorre C |
| Ref : Bioorganic & Medicinal Chemistry , 8 :681 , 2000 |
| Abstract : Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| ESTHER : Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| PubMedSearch : Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| PubMedID: 10819156 |
| Title : Design, synthesis, and biological evaluation of symmetrically and unsymmetrically substituted methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists - Rosini_1999_J.Med.Chem_42_5212 |
| Author(s) : Rosini M , Budriesi R , Bixel MG , Bolognesi ML , Chiarini A , Hucho F , Krogsgaard-Larsen P , Mellor IR , Minarini A , Tumiatti V , Usherwood PN , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 42 :5212 , 1999 |
| Abstract : Rosini_1999_J.Med.Chem_42_5212 |
| ESTHER : Rosini_1999_J.Med.Chem_42_5212 |
| PubMedSearch : Rosini_1999_J.Med.Chem_42_5212 |
| PubMedID: 10602706 |
| Title : Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone for Potential Use against Alzheimer's Disease - |
| Author(s) : Melchiorre C , Andrisano V , Bolognesi ML , Budriesi R , Cavalli A , Cavrini V , Rosini M , Tumiatti V , Recanatini M |
| Ref : Journal of Medicinal Chemistry , 41 :4186 , 1998 |
| PubMedID: 9784091 |