Full name : Jung Young-Sik
First name : Young-Sik
Mail : Medicinal Science Division, Korea Research Institute of Chemical Technology, PO Box 107, Yusong, Daejeon 305-606
Zip Code :
City :
Country : Korea
Email : ysjung@krict.re.kr
Phone :
Fax :
Website :
Directory :
| Title : Discovery of (E)-2-(Hydroxyimino)-N-(2 ((4methylpentyl)amino)ethyl)acetamide (KR-27425) as a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase - Vishakantegowda_2023_Bioorg.Med.Chem.Lett__129504 |
| Author(s) : Vishakantegowda AG , Solomon Girmay B , Soo Shin J , Lee JY , Ahn S , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , :129504 , 2023 |
| Abstract : Vishakantegowda_2023_Bioorg.Med.Chem.Lett__129504 |
| ESTHER : Vishakantegowda_2023_Bioorg.Med.Chem.Lett__129504 |
| PubMedSearch : Vishakantegowda_2023_Bioorg.Med.Chem.Lett__129504 |
| PubMedID: 37838342 |
| Title : Neuroprotective effects of ethanolic extract from dry Rhodiola rosea L. rhizomes - Kim_2021_Food.Sci.Biotechnol_30_287 |
| Author(s) : Kim KJ , Jung YS , You DM , Lee SH , Lee G , Kwon KB , Kim DO |
| Ref : Food Sci Biotechnol , 30 :287 , 2021 |
| Abstract : Kim_2021_Food.Sci.Biotechnol_30_287 |
| ESTHER : Kim_2021_Food.Sci.Biotechnol_30_287 |
| PubMedSearch : Kim_2021_Food.Sci.Biotechnol_30_287 |
| PubMedID: 33732519 |
| Title : Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase - Jonczyk_2021_Biomolecules_11_ |
| Author(s) : Jonczyk J , Kukulowicz J , Aatka K , Malawska B , Jung YS , Musilek K , Bajda M |
| Ref : Biomolecules , 11 : , 2021 |
| Abstract : Jonczyk_2021_Biomolecules_11_ |
| ESTHER : Jonczyk_2021_Biomolecules_11_ |
| PubMedSearch : Jonczyk_2021_Biomolecules_11_ |
| PubMedID: 33513955 |
| Title : Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates - Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| Author(s) : Lee HM , Andrys R , Jonczyk J , Kim K , Vishakantegowda AG , Malinak D , Skarka A , Schmidt M , Vaskova M , Latka K , Bajda M , Jung YS , Malawska B , Musilek K |
| Ref : J Enzyme Inhib Med Chem , 36 :437 , 2021 |
| Abstract : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| ESTHER : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| PubMedSearch : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| PubMedID: 33467931 |
| Title : Pharmacokinetics of K117 and K127, two novel antidote candidates to treat Tabun poisoning - Tekes_2019_Chem.Biol.Interact_13ChEPon_310_108737 |
| Author(s) : Tekes K , Karvaly G , Nurulain S , Kuca K , Musilek K , Adeghate E , Jung YS , Kalasz H |
| Ref : Chemico-Biological Interactions , 310 :108737 , 2019 |
| Abstract : Tekes_2019_Chem.Biol.Interact_13ChEPon_310_108737 |
| ESTHER : Tekes_2019_Chem.Biol.Interact_13ChEPon_310_108737 |
| PubMedSearch : Tekes_2019_Chem.Biol.Interact_13ChEPon_310_108737 |
| PubMedID: 31279792 |
| Title : Anti-Oxidant Activity of Gallotannin-Enriched Extract of Galla Rhois Can Associate with the Protection of the Cognitive Impairment through the Regulation of BDNF Signaling Pathway and Neuronal Cell Function in the Scopolamine-Treated ICR Mice - Park_2019_Antioxidants.(Basel)_8_ |
| Author(s) : Park JW , Kim JE , Kang MJ , Choi HJ , Bae SJ , Kim SH , Jung YS , Hong JT , Hwang DY |
| Ref : Antioxidants (Basel) , 8 : , 2019 |
| Abstract : Park_2019_Antioxidants.(Basel)_8_ |
| ESTHER : Park_2019_Antioxidants.(Basel)_8_ |
| PubMedSearch : Park_2019_Antioxidants.(Basel)_8_ |
| PubMedID: 31623364 |
| Title : Comparison of scopolamine-induced cognitive impairment responses in three different ICR stocks - Yoon_2018_Lab.Anim.Res_34_317 |
| Author(s) : Yoon WB , Choi HJ , Kim JE , Park JW , Kang MJ , Bae SJ , Lee YJ , Choi YS , Kim KS , Jung YS , Cho JY , Hwang DY , Song HK |
| Ref : Lab Anim Res , 34 :317 , 2018 |
| Abstract : Yoon_2018_Lab.Anim.Res_34_317 |
| ESTHER : Yoon_2018_Lab.Anim.Res_34_317 |
| PubMedSearch : Yoon_2018_Lab.Anim.Res_34_317 |
| PubMedID: 30671121 |
| Title : Novel tacrine-pyridinium hybrid reactivators of organophosphorus-inhibited acetylcholinesterase: Synthesis, molecular docking, and in vitro reactivation study - Kim_2018_Bioorg.Med.Chem.Lett_28_3784 |
| Author(s) : Kim J , Malpani YR , Lee J , Shin JS , Han SB , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 28 :3784 , 2018 |
| Abstract : Kim_2018_Bioorg.Med.Chem.Lett_28_3784 |
| ESTHER : Kim_2018_Bioorg.Med.Chem.Lett_28_3784 |
| PubMedSearch : Kim_2018_Bioorg.Med.Chem.Lett_28_3784 |
| PubMedID: 30301674 |
| Title : Neuroprotective Effects of Korean Red Pine (Pinus densiflora) Bark Extract and Its Phenolics - Kim_2018_J.Microbiol.Biotechnol_28_679 |
| Author(s) : Kim JW , Im S , Jeong HR , Jung YS , Lee I , Kim KJ , Park SK , Kim DO |
| Ref : J Microbiol Biotechnol , 28 :679 , 2018 |
| Abstract : Kim_2018_J.Microbiol.Biotechnol_28_679 |
| ESTHER : Kim_2018_J.Microbiol.Biotechnol_28_679 |
| PubMedSearch : Kim_2018_J.Microbiol.Biotechnol_28_679 |
| PubMedID: 29539881 |
| Title : Cognitive-Enhancing Effect of Dianthus superbus var. Longicalycinus on Scopolamine-Induced Memory Impairment in Mice - Weon_2016_Biomol.Ther.(Seoul)_24_298 |
| Author(s) : Weon JB , Jung YS , Ma CJ |
| Ref : Biomol Ther (Seoul) , 24 :298 , 2016 |
| Abstract : Weon_2016_Biomol.Ther.(Seoul)_24_298 |
| ESTHER : Weon_2016_Biomol.Ther.(Seoul)_24_298 |
| PubMedSearch : Weon_2016_Biomol.Ther.(Seoul)_24_298 |
| PubMedID: 27133261 |
| Title : Cognitive enhancing effect of the fermented Gumiganghwal-tang on scopolamine-induced memory impairment in mice - Weon_2016_Nutr.Neurosci_19_125 |
| Author(s) : Weon JB , Lee J , Eom MR , Jung YS , Ma CJ |
| Ref : Nutr Neurosci , 19 :125 , 2016 |
| Abstract : Weon_2016_Nutr.Neurosci_19_125 |
| ESTHER : Weon_2016_Nutr.Neurosci_19_125 |
| PubMedSearch : Weon_2016_Nutr.Neurosci_19_125 |
| PubMedID: 25216329 |
| Title : Steamed and Fermented Ethanolic Extract from Codonopsis lanceolata Attenuates Amyloid-beta-Induced Memory Impairment in Mice - Weon_2016_Evid.Based.Complement.Alternat.Med_2016_1473801 |
| Author(s) : Weon JB , Eom MR , Jung YS , Hong EH , Ko HJ , Lee HY , Park DS , Ma CJ |
| Ref : Evid Based Complement Alternat Med , 2016 :1473801 , 2016 |
| Abstract : Weon_2016_Evid.Based.Complement.Alternat.Med_2016_1473801 |
| ESTHER : Weon_2016_Evid.Based.Complement.Alternat.Med_2016_1473801 |
| PubMedSearch : Weon_2016_Evid.Based.Complement.Alternat.Med_2016_1473801 |
| PubMedID: 27313637 |
| Title : Cognitive-Enhancing Effect of Aronia melanocarpa Extract against Memory Impairment Induced by Scopolamine in Mice - Lee_2016_Evid.Based.Complement.Alternat.Med_2016_6145926 |
| Author(s) : Lee HY , Weon JB , Jung YS , Kim NY , Kim MK , Ma CJ |
| Ref : Evid Based Complement Alternat Med , 2016 :6145926 , 2016 |
| Abstract : Lee_2016_Evid.Based.Complement.Alternat.Med_2016_6145926 |
| ESTHER : Lee_2016_Evid.Based.Complement.Alternat.Med_2016_6145926 |
| PubMedSearch : Lee_2016_Evid.Based.Complement.Alternat.Med_2016_6145926 |
| PubMedID: 27239211 |
| Title : Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors--analogues of SAD-128 - Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| Author(s) : Musilek K , Roder J , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Opletalova V , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :150 , 2011 |
| Abstract : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| ESTHER : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| PubMedSearch : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| PubMedID: 21144749 |
| Title : Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties - Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| Author(s) : Korabecny J , Musilek K , Zemek F , Horova A , Holas O , Nepovimova E , Opletalova V , Hroudova J , Fisar Z , Jung YS , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :6563 , 2011 |
| Abstract : Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| ESTHER : Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| PubMedSearch : Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| PubMedID: 21920739 |
| Title : Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications - Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| Author(s) : Musilek K , Komloova M , Zavadova V , Holas O , Hrabinova M , Pohanka M , Dohnal V , Nachon F , Dolezal M , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1763 , 2010 |
| Abstract : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| ESTHER : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| PubMedSearch : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| PubMedID: 20138518 |
| Title : Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase - Kovarik_2010_Chem.Biol.Interact_187_167 |
| Author(s) : Kovarik Z , Katalinic M , Sinko G , Binder J , Holas O , Jung YS , Musilova L , Jun D , Kuca K |
| Ref : Chemico-Biological Interactions , 187 :167 , 2010 |
| Abstract : Kovarik_2010_Chem.Biol.Interact_187_167 |
| ESTHER : Kovarik_2010_Chem.Biol.Interact_187_167 |
| PubMedSearch : Kovarik_2010_Chem.Biol.Interact_187_167 |
| PubMedID: 20206154 |
| Title : A Comparison of Neuroprotective Efficacy of the Oxime K203 and its Fluorinated Analogue (KR-22836) with Obidoxime in Tabun-Poisoned Rats - Kassa_2010_Basic.Clin.Pharmacol.Toxicol_107_861 |
| Author(s) : Kassa J , Karasova JZ , Tesarova S , Musilek K , Kuca K , Jung YS |
| Ref : Basic Clin Pharmacol Toxicol , 107 :861 , 2010 |
| Abstract : Kassa_2010_Basic.Clin.Pharmacol.Toxicol_107_861 |
| ESTHER : Kassa_2010_Basic.Clin.Pharmacol.Toxicol_107_861 |
| PubMedSearch : Kassa_2010_Basic.Clin.Pharmacol.Toxicol_107_861 |
| PubMedID: 22545968 |
| Title : A comparison of reactivating and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice - Kassa_2010_J.Enzyme.Inhib.Med.Chem_25_480 |
| Author(s) : Kassa J , Karasova JZ , Caisberger F , Musilek K , Kuca K , Jung YS |
| Ref : J Enzyme Inhib Med Chem , 25 :480 , 2010 |
| Abstract : Kassa_2010_J.Enzyme.Inhib.Med.Chem_25_480 |
| ESTHER : Kassa_2010_J.Enzyme.Inhib.Med.Chem_25_480 |
| PubMedSearch : Kassa_2010_J.Enzyme.Inhib.Med.Chem_25_480 |
| PubMedID: 20233085 |
| Title : Reactivation of human brain homogenate cholinesterases inhibited by Tabun using newly developed oximes K117 and K127 - Kuca_2009_Basic.Clin.Pharmacol.Toxicol_105_207 |
| Author(s) : Kuca K , Cabal J , Jung YS , Musilek K , Soukup O , Jun D , Pohanka M , Musilova L , Karasova J , Novotny L , Hrabinova M |
| Ref : Basic Clin Pharmacol Toxicol , 105 :207 , 2009 |
| Abstract : Kuca_2009_Basic.Clin.Pharmacol.Toxicol_105_207 |
| ESTHER : Kuca_2009_Basic.Clin.Pharmacol.Toxicol_105_207 |
| PubMedSearch : Kuca_2009_Basic.Clin.Pharmacol.Toxicol_105_207 |
| PubMedID: 19473310 |
| Title : Fluorinated pyridinium oximes as potential reactivators for acetylcholinesterases inhibited by paraoxon organophosphorus agent - Jeong_2009_Bioorg.Med.Chem_17_6213 |
| Author(s) : Jeong HC , Park NJ , Chae CH , Musilek K , Kassa J , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry , 17 :6213 , 2009 |
| Abstract : Jeong_2009_Bioorg.Med.Chem_17_6213 |
| ESTHER : Jeong_2009_Bioorg.Med.Chem_17_6213 |
| PubMedSearch : Jeong_2009_Bioorg.Med.Chem_17_6213 |
| PubMedID: 19665386 |
| Title : A comparison of the therapeutic and reactivating efficacy of newly developed oximes (K117, K127) and currently available oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice - Kassa_2008_Drug.Chem.Toxicol_31_371 |
| Author(s) : Kassa J , Karasova J , Musilek K , Kuca K , Jung YS |
| Ref : Drug & Chemical Toxicology , 31 :371 , 2008 |
| Abstract : Kassa_2008_Drug.Chem.Toxicol_31_371 |
| ESTHER : Kassa_2008_Drug.Chem.Toxicol_31_371 |
| PubMedSearch : Kassa_2008_Drug.Chem.Toxicol_31_371 |
| PubMedID: 18622871 |
| Title : Effect of several new and currently available oxime cholinesterase reactivators on tabun-intoxicated rats - Karasova_2008_Int.J.Mol.Sci_9_2243 |
| Author(s) : Karasova JZ , Kassa J , Jung YS , Musilek K , Pohanka M , Kuca K |
| Ref : Int J Mol Sci , 9 :2243 , 2008 |
| Abstract : Karasova_2008_Int.J.Mol.Sci_9_2243 |
| ESTHER : Karasova_2008_Int.J.Mol.Sci_9_2243 |
| PubMedSearch : Karasova_2008_Int.J.Mol.Sci_9_2243 |
| PubMedID: 19330072 |
| Title : Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes - Oh_2008_Chem.Biol.Interact_175_365 |
| Author(s) : Oh KA , Park NJ , Park NS , Kuca K , Jun D , Jung YS |
| Ref : Chemico-Biological Interactions , 175 :365 , 2008 |
| Abstract : Oh_2008_Chem.Biol.Interact_175_365 |
| ESTHER : Oh_2008_Chem.Biol.Interact_175_365 |
| PubMedSearch : Oh_2008_Chem.Biol.Interact_175_365 |
| PubMedID: 18565503 |
| Title : New oxime reactivators connected with CH2O(CH2)nOCH2 linker and their reactivation potency for organophosphorus agents-inhibited acetylcholinesterase - Yang_2007_Bioorg.Med.Chem_15_7704 |
| Author(s) : Yang GY , Oh KA , Park NJ , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry , 15 :7704 , 2007 |
| Abstract : Yang_2007_Bioorg.Med.Chem_15_7704 |
| ESTHER : Yang_2007_Bioorg.Med.Chem_15_7704 |
| PubMedSearch : Yang_2007_Bioorg.Med.Chem_15_7704 |
| PubMedID: 17869525 |
| Title : [Synthesis of reactivators of phosphorylated acetylcholinesterase of bis-pyridiniumdialdoxime type with a 3-oxapentane connecting chain and their testing in vitro on a model of the enzyme inhibited by chlorpyrifos and methylchlorpyrifos] - Musilek_2006_Ceska.Slov.Farm_55_115 |
| Author(s) : Musilek K , Kuca K , Jun D , Dohnal V , Kim TH , Jung YS , Dolezal M |
| Ref : Ceska a Slovenska Farmacie , 55 :115 , 2006 |
| Abstract : Musilek_2006_Ceska.Slov.Farm_55_115 |
| ESTHER : Musilek_2006_Ceska.Slov.Farm_55_115 |
| PubMedSearch : Musilek_2006_Ceska.Slov.Farm_55_115 |
| PubMedID: 16838488 |
| Title : Amylase level in extrahepatic bile duct in adult patients with choledochal cyst plus anomalous pancreatico-biliary ductal union - Jeong_2005_World.J.Gastroenterol_11_1965 |
| Author(s) : Jeong IH , Jung YS , Kim H , Kim BW , Kim JW , Hong J , Wang HJ , Kim MW , Yoo BM , Kim JH , Han JH , Kim WH |
| Ref : World J Gastroenterol , 11 :1965 , 2005 |
| Abstract : Jeong_2005_World.J.Gastroenterol_11_1965 |
| ESTHER : Jeong_2005_World.J.Gastroenterol_11_1965 |
| PubMedSearch : Jeong_2005_World.J.Gastroenterol_11_1965 |
| PubMedID: 15800987 |
| Title : Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents - Kim_2005_Bioorg.Med.Chem.Lett_15_2914 |
| Author(s) : Kim TH , Kuca K , Jun D , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :2914 , 2005 |
| Abstract : Kim_2005_Bioorg.Med.Chem.Lett_15_2914 |
| ESTHER : Kim_2005_Bioorg.Med.Chem.Lett_15_2914 |
| PubMedSearch : Kim_2005_Bioorg.Med.Chem.Lett_15_2914 |
| PubMedID: 15911280 |
| Title : N-nitrosocarbofuran induces apoptosis in mouse brain microvascular endothelial cells (bEnd.3) - Jung_2003_J.Pharmacol.Sci_93_489 |
| Author(s) : Jung YS , Kim CS , Park HS , Sohn S , Lee BH , Moon CK , Lee SH , Baik EJ , Moon CH |
| Ref : J Pharmacol Sci , 93 :489 , 2003 |
| Abstract : Jung_2003_J.Pharmacol.Sci_93_489 |
| ESTHER : Jung_2003_J.Pharmacol.Sci_93_489 |
| PubMedSearch : Jung_2003_J.Pharmacol.Sci_93_489 |
| PubMedID: 14737022 |