Full name : Harel Michal
First name : Michal
Mail : Weizmann Institute of Science Structural Biology, Rehovot 76100
Zip Code :
City :
Country : Israel
Email : michal.harel@weizmann.ac.il
Phone : 972-8-9342647
Fax : 972-8-9344159
Website :
Directory :
| Title : Proteopedia: a status report on the collaborative, 3D web-encyclopedia of proteins and other biomolecules - Prilusky_2011_J.Struct.Biol_175_244 |
| Author(s) : Prilusky J , Hodis E , Canner D , Decatur WA , Oberholser K , Martz E , Berchanski A , Harel M , Sussman JL |
| Ref : J Struct Biol , 175 :244 , 2011 |
| Abstract : Prilusky_2011_J.Struct.Biol_175_244 |
| ESTHER : Prilusky_2011_J.Struct.Biol_175_244 |
| PubMedSearch : Prilusky_2011_J.Struct.Biol_175_244 |
| PubMedID: 21536137 |
| Title : Acetylcholinesterase: from 3D structure to function - Dvir_2010_Chem.Biol.Interact_187_10 |
| Author(s) : Dvir H , Silman I , Harel M , Rosenberry TL , Sussman JL |
| Ref : Chemico-Biological Interactions , 187 :10 , 2010 |
| Abstract : Dvir_2010_Chem.Biol.Interact_187_10 |
| ESTHER : Dvir_2010_Chem.Biol.Interact_187_10 |
| PubMedSearch : Dvir_2010_Chem.Biol.Interact_187_10 |
| PubMedID: 20138030 |
| Gene_locus related to this paper: human-ACHE |
| Title : Microcalorimetric study of the inhibition of butyrylcholinesterase by paraoxon - Debord_2009_Anal.Biochem_389_97 |
| Author(s) : Debord J , Harel M , Verneuil B , Bollinger JC , Dantoine T |
| Ref : Analytical Biochemistry , 389 :97 , 2009 |
| Abstract : Debord_2009_Anal.Biochem_389_97 |
| ESTHER : Debord_2009_Anal.Biochem_389_97 |
| PubMedSearch : Debord_2009_Anal.Biochem_389_97 |
| PubMedID: 19341699 |
| Title : Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore - Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606 |
| Author(s) : Talley TT , Harel M , Hibbs RE , Radic Z , Tomizawa M , Casida JE , Taylor P |
| Ref : Proc Natl Acad Sci U S A , 105 :7606 , 2008 |
| Abstract : Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606 |
| ESTHER : Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606 |
| PubMedSearch : Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606 |
| PubMedID: 18477694 |
| Title : Crystal structure of thioflavin T bound to the peripheral site of Torpedo californica acetylcholinesterase reveals how thioflavin T acts as a sensitive fluorescent reporter of ligand binding to the acylation site - Harel_2008_J.Am.Chem.Soc_130_7856 |
| Author(s) : Harel M , Sonoda LK , Silman I , Sussman JL , Rosenberry TL |
| Ref : Journal of the American Chemical Society , 130 :7856 , 2008 |
| Abstract : Harel_2008_J.Am.Chem.Soc_130_7856 |
| ESTHER : Harel_2008_J.Am.Chem.Soc_130_7856 |
| PubMedSearch : Harel_2008_J.Am.Chem.Soc_130_7856 |
| PubMedID: 18512913 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11 - Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| Author(s) : Hyatt JL , Tsurkan L , Morton CL , Yoon KJ , Harel M , Brumshtein B , Silman I , Sussman JL , Wadkins RM , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :247 , 2005 |
| Abstract : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| ESTHER : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedSearch : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedID: 16257398 |
| Title : The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase - Harel_2005_Chem.Biol.Interact_157-158_153 |
| Author(s) : Harel M , Hyatt JL , Brumshtein B , Morton CL , Wadkins RM , Silman I , Sussman JL , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :153 , 2005 |
| Abstract : Harel_2005_Chem.Biol.Interact_157-158_153 |
| ESTHER : Harel_2005_Chem.Biol.Interact_157-158_153 |
| PubMedSearch : Harel_2005_Chem.Biol.Interact_157-158_153 |
| PubMedID: 16289500 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action - Harel_2005_Mol.Pharmacol_67_1874 |
| Author(s) : Harel M , Hyatt JL , Brumshtein B , Morton CL , Yoon KJ , Wadkins RM , Silman I , Sussman JL , Potter PM |
| Ref : Molecular Pharmacology , 67 :1874 , 2005 |
| Abstract : Harel_2005_Mol.Pharmacol_67_1874 |
| ESTHER : Harel_2005_Mol.Pharmacol_67_1874 |
| PubMedSearch : Harel_2005_Mol.Pharmacol_67_1874 |
| PubMedID: 15772291 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal structure of the tetramerization domain of acetylcholinesterase at 2. - |
| Author(s) : Harel M , Dvir H , Bon S , Liu WQ , Garbay C , Sussman JL , Massoulie J , Silman I |
| Ref : Cholinergic Mechanisms, CRC Press :183 , 2004 |
| PubMedID: |
| Title : Poster (79) X-ray structures of TcAChE complexed with (+)-huperzine a and (-)-huperzine b: structural evidence for an active-site rearrangement - |
| Author(s) : Dvir H , Jiang H , Wong DM , Harel M , Chetrit M , He XC , Jin GY , Yu GL , Tang XC , Silman I , Bai DL , Sussman JL |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :362 , 2004 |
| PubMedID: |
| Title : Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes - Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| Author(s) : Harel M , Aharoni A , Gaidukov L , Brumshtein B , Khersonsky O , Meged R , Dvir H , Ravelli RB , McCarthy A , Toker L , Silman I , Sussman JL , Tawfik DS |
| Ref : Nat Struct Mol Biol , 11 :412 , 2004 |
| Abstract : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| ESTHER : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| PubMedSearch : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| PubMedID: 15098021 |
| Title : The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix - Dvir_2004_EMBO.J_23_4394 |
| Author(s) : Dvir H , Harel M , Bon S , Liu WQ , Vidal M , Garbay C , Sussman JL , Massoulie J , Silman I |
| Ref : EMBO Journal , 23 :4394 , 2004 |
| Abstract : Dvir_2004_EMBO.J_23_4394 |
| ESTHER : Dvir_2004_EMBO.J_23_4394 |
| PubMedSearch : Dvir_2004_EMBO.J_23_4394 |
| PubMedID: 15526038 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The binding site for alpha-bungarotoxin in the acetylcholine receptor. - |
| Author(s) : Fuchs S , Kasher R , Balass M , Scherf T , Harel M , Fridkin M , Sussman JL , Katchalski-Katzir E |
| Ref : Cholinergic Mechanisms, CRC Press :19 , 2004 |
| PubMedID: |
| Title : Poster (48) Crystal structure of the tetramerization domain of acetylcholinesterase reveals a model of the AChE tetramer - |
| Author(s) : Harel M , Dvir H , Bon S , Liu WQ , Garbay C , Sussman JL , Massoulie J , Silman I |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :347 , 2004 |
| PubMedID: |
| Title : A distinct family of acetylcholinesterases is secreted by Nippostrongylus brasiliensis - Hussein_2002_Mol.Biochem.Parasitol_123_125 |
| Author(s) : Hussein AS , Harel M , Selkirk ME |
| Ref : Molecular & Biochemical Parasitology , 123 :125 , 2002 |
| Abstract : Hussein_2002_Mol.Biochem.Parasitol_123_125 |
| ESTHER : Hussein_2002_Mol.Biochem.Parasitol_123_125 |
| PubMedSearch : Hussein_2002_Mol.Biochem.Parasitol_123_125 |
| PubMedID: 12270628 |
| Gene_locus related to this paper: nipbr-ACHEA |
| Title : Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine - Bar-On_2002_Biochemistry_41_3555 |
| Author(s) : Bar-On P , Millard CB , Harel M , Dvir H , Enz A , Sussman JL , Silman I |
| Ref : Biochemistry , 41 :3555 , 2002 |
| Abstract : Bar-On_2002_Biochemistry_41_3555 |
| ESTHER : Bar-On_2002_Biochemistry_41_3555 |
| PubMedSearch : Bar-On_2002_Biochemistry_41_3555 |
| PubMedID: 11888271 |
| Gene_locus related to this paper: torca-ACHE |
| Title : 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates - Dvir_2002_Biochemistry_41_2970 |
| Author(s) : Dvir H , Wong DM , Harel M , Barril X , Orozco M , Luque FJ , Munoz-Torrero D , Camps P , Rosenberry TL , Silman I , Sussman JL |
| Ref : Biochemistry , 41 :2970 , 2002 |
| Abstract : Dvir_2002_Biochemistry_41_2970 |
| ESTHER : Dvir_2002_Biochemistry_41_2970 |
| PubMedSearch : Dvir_2002_Biochemistry_41_2970 |
| PubMedID: 11863435 |
| Gene_locus related to this paper: torca-ACHE |
| Title : X-ray Structures of Torpedo californica Acetylcholinesterase Complexed with (+)-Huperzine A and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement - Dvir_2002_Biochemistry_41_10810 |
| Author(s) : Dvir H , Jiang H , Wong DM , Harel M , Chetrit M , He XC , Jin GY , Yu GL , Tang XC , Silman I , Bai DL , Sussman JL |
| Ref : Biochemistry , 41 :10810 , 2002 |
| Abstract : Dvir_2002_Biochemistry_41_10810 |
| ESTHER : Dvir_2002_Biochemistry_41_10810 |
| PubMedSearch : Dvir_2002_Biochemistry_41_10810 |
| PubMedID: 12196020 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase - Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| Author(s) : Felder CE , Harel M , Silman I , Sussman JL |
| Ref : Acta Crystallographica D Biol Crystallogr , 58 :1765 , 2002 |
| Abstract : Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| ESTHER : Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| PubMedSearch : Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| PubMedID: 12351819 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors - Harel_2000_Protein.Sci_9_1063 |
| Author(s) : Harel M , Kryger G , Rosenberry TL , Mallender WD , Lewis T , Fletcher RJ , Guss JM , Silman I , Sussman JL |
| Ref : Protein Science , 9 :1063 , 2000 |
| Abstract : Harel_2000_Protein.Sci_9_1063 |
| ESTHER : Harel_2000_Protein.Sci_9_1063 |
| PubMedSearch : Harel_2000_Protein.Sci_9_1063 |
| PubMedID: 10892800 |
| Gene_locus related to this paper: drome-ACHE |
| Title : Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II - Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| Author(s) : Kryger G , Harel M , Giles K , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL |
| Ref : Acta Crystallographica D Biol Crystallogr , 56 :1385 , 2000 |
| Abstract : Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| ESTHER : Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| PubMedSearch : Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| PubMedID: 11053835 |
| Gene_locus related to this paper: human-ACHE |
| Title : Specific chemical and structural damage to proteins produced by synchrotron radiation - Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| Author(s) : Weik M , Ravelli RB , Kryger G , McSweeney S , Raves ML , Harel M , Gros P , Silman I , Kroon J , Sussman JL |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 97 :623 , 2000 |
| Abstract : Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| ESTHER : Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| PubMedSearch : Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| PubMedID: 10639129 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level - Millard_1999_Biochemistry_38_7032 |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Greenblatt HM , Harel M , Raves ML , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : Biochemistry , 38 :7032 , 1999 |
| Abstract : Millard_1999_Biochemistry_38_7032 |
| ESTHER : Millard_1999_Biochemistry_38_7032 |
| PubMedSearch : Millard_1999_Biochemistry_38_7032 |
| PubMedID: 10353814 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A preliminary comparison of structural models for catalytic intermediates of acetylcholinesterase - Silman_1999_Chem.Biol.Interact_119-120_43 |
| Author(s) : Silman I , Millard CB , Ordentlich A , Greenblatt HM , Harel M , Barak D , Shafferman A , Sussman JL |
| Ref : Chemico-Biological Interactions , 119-120 :43 , 1999 |
| Abstract : Silman_1999_Chem.Biol.Interact_119-120_43 |
| ESTHER : Silman_1999_Chem.Biol.Interact_119-120_43 |
| PubMedSearch : Silman_1999_Chem.Biol.Interact_119-120_43 |
| PubMedID: 10421437 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal Structures of Aged Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :425 , 1998 |
| PubMedID: |
| Title : Crystal Structures of Aged Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :454 , 1998 |
| PubMedID: |
| Title : Kinetic and structural studies on the interaction of the anti-Alzheimer drug, ENA-713, with Torpedo californica acetylcholinesterase - |
| Author(s) : Bar-On P , Harel M , Millard CB , Enz A , Sussman JL , Silman I |
| Ref : Journal de Physiologie (Paris) , 92 :406 , 1998 |
| PubMedID: |
| Title : Crystal structure of Aged phosphorylated and phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :425 , 1998 |
| PubMedID: |
| Gene_locus related to this paper: torca-ACHE |
| Title : 3D Structure at 2.7 Resolution of Native and E202Q Mutant Human Acetylcholinesterase Complexed with Fasciculin-II - |
| Author(s) : Kryger G , Giles K , Harel M , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :323 , 1998 |
| PubMedID: |
| Title : 3D Structure of a Complex of Human Acetylcholinesterase with Fasciculin-II at 2.7 Resolution - |
| Author(s) : Kryger G , Giles K , Harel M , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :370 , 1998 |
| PubMedID: |
| Title : Crystal Structures of Complexes of E2020-Related Compounds with Torpedo Californica Acetylcholinesterase - |
| Author(s) : Greenblatt HM , Kryger G , Harel M , Lewis T , Taylor J , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :371-371 , 1998 |
| PubMedID: |
| Title : Alternative Crystal Forms of Torpedo Californica Acetylcholinesterase - |
| Author(s) : Raves ML , Greenblatt HM , Kryger G , Nicolas A , Ravelli RB , Harel M , Kroon J , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :372 , 1998 |
| PubMedID: |
| Title : Kinetic and X-Ray Crystallographic Studies of the Binding of ENA-713 to Torpedo Californica Acetylcholinesterase - |
| Author(s) : Bar-On P , Harel M , Millard CB , Enz A , Sussman JL , Silman I |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :373 , 1998 |
| PubMedID: |
| Title : Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A - Raves_1997_Nat.Struct.Biol_4_57 |
| Author(s) : Raves ML , Harel M , Pang YP , Silman I , Kozikowski AP , Sussman JL |
| Ref : Nat Struct Biol , 4 :57 , 1997 |
| Abstract : Raves_1997_Nat.Struct.Biol_4_57 |
| ESTHER : Raves_1997_Nat.Struct.Biol_4_57 |
| PubMedSearch : Raves_1997_Nat.Struct.Biol_4_57 |
| PubMedID: 8989325 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase. - |
| Author(s) : Harel M , Quinn DM , Nair HK , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 118 :2340 , 1996 |
| PubMedID: |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target - Harel_1995_Structure_3_1355 |
| Author(s) : Harel M , Kleywegt GJ , Ravelli RB , Silman I , Sussman JL |
| Ref : Structure , 3 :1355 , 1995 |
| Abstract : Harel_1995_Structure_3_1355 |
| ESTHER : Harel_1995_Structure_3_1355 |
| PubMedSearch : Harel_1995_Structure_3_1355 |
| PubMedID: 8747462 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structures of Complexes of Acetylcholinesterase with Covalently and Non-Covalently Bound Inhibitors - |
| Author(s) : Sussman JL , Harel M , Raves ML , Quinn DM , Nair HK , Silman I |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :59 , 1995 |
| PubMedID: |
| Title : Structure and dynamics of the active site gorge of acetylcholinesterase: synergistic use of molecular dynamics simulation and X-ray crystallography - Axelsen_1994_Prot.Sci_3_188 |
| Author(s) : Axelsen PH , Harel M , Silman I , Sussman JL |
| Ref : Protein Science , 3 :188 , 1994 |
| Abstract : Axelsen_1994_Prot.Sci_3_188 |
| ESTHER : Axelsen_1994_Prot.Sci_3_188 |
| PubMedSearch : Axelsen_1994_Prot.Sci_3_188 |
| PubMedID: 8003956 |
| Title : Three-dimensional structures of acetylcholinesterase and of its complexes with anticholinesterase agents - |
| Author(s) : Silman I , Harel M , Axelsen PH , Raves ML , Sussman JL |
| Ref : Biochemical Society Transactions , 22 :745 , 1994 |
| PubMedID: 7821677 |
| Title : Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins - Cygler_1993_Protein.Sci_2_366 |
| Author(s) : Cygler M , Schrag JD , Sussman JL , Harel M , Silman I , Gentry MK , Doctor BP |
| Ref : Protein Science , 2 :366 , 1993 |
| Abstract : Cygler_1993_Protein.Sci_2_366 |
| ESTHER : Cygler_1993_Protein.Sci_2_366 |
| PubMedSearch : Cygler_1993_Protein.Sci_2_366 |
| PubMedID: 8453375 |
| Title : Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase - Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| Author(s) : Harel M , Schalk I , Ehret-Sabatier L , Bouet F , Goeldner M , Hirth C , Axelsen PH , Silman I , Sussman JL |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 90 :9031 , 1993 |
| Abstract : Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| ESTHER : Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| PubMedSearch : Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| PubMedID: 8415649 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs - Sussman_1993_Chem.Biol.Interact_87_187 |
| Author(s) : Sussman JL , Harel M , Silman I |
| Ref : Chemico-Biological Interactions , 87 :187 , 1993 |
| Abstract : Sussman_1993_Chem.Biol.Interact_87_187 |
| ESTHER : Sussman_1993_Chem.Biol.Interact_87_187 |
| PubMedSearch : Sussman_1993_Chem.Biol.Interact_87_187 |
| PubMedID: 8343975 |
| Title : Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis - Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| Author(s) : Harel M , Sussman JL , Krejci E , Bon S , Chanal P , Massoulie J , Silman I |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 89 :10827 , 1992 |
| Abstract : Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| ESTHER : Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| PubMedSearch : Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| PubMedID: 1438284 |
| Title : Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding - Shafferman_1992_J.Biol.Chem_267_17640 |
| Author(s) : Shafferman A , Kronman C , Flashner Y , Leitner M , Grosfeld H , Ordentlich A , Gozes Y , Cohen S , Ariel N , Barak D , Harel M , Silman I , Sussman JL , Velan B |
| Ref : Journal of Biological Chemistry , 267 :17640 , 1992 |
| Abstract : Shafferman_1992_J.Biol.Chem_267_17640 |
| ESTHER : Shafferman_1992_J.Biol.Chem_267_17640 |
| PubMedSearch : Shafferman_1992_J.Biol.Chem_267_17640 |
| PubMedID: 1517212 |
| Title : The alpha\/beta hydrolase fold - Ollis_1992_Prot.Engin_5_197 |
| Author(s) : Ollis DL , Cheah E , Cygler M , Dijkstra B , Frolow F , Franken SM , Harel M , Remington SJ , Silman I , Schrag JD , Sussman JL , Verschueren KHG , Goldman A |
| Ref : Protein Engineering , 5 :197 , 1992 |
| Abstract : Ollis_1992_Prot.Engin_5_197 |
| ESTHER : Ollis_1992_Prot.Engin_5_197 |
| PubMedSearch : Ollis_1992_Prot.Engin_5_197 |
| PubMedID: 1409539 |
| Title : Three Dimensional Structure of Acetylcholinesterase - |
| Author(s) : Sussman JL , Harel M , Silman I |
| Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :95 , 1992 |
| PubMedID: |
| Title : A Model of Butyrylcholinesterase Based on the X-Ray Structure of Acetylcholinesterase Indicates Differences in Specificity - |
| Author(s) : Harel M , Silman I , Sussman JL |
| Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :189 , 1992 |
| PubMedID: |
| Title : Refined crystal structures of aged and non-aged organophosphoryl conjugates of gamma-chymotrypsin - Harel_1991_J.Mol.Biol_221_909 |
| Author(s) : Harel M , Su CT , Frolow F , Ashani Y , Silman I , Sussman JL |
| Ref : Journal of Molecular Biology , 221 :909 , 1991 |
| Abstract : Harel_1991_J.Mol.Biol_221_909 |
| ESTHER : Harel_1991_J.Mol.Biol_221_909 |
| PubMedSearch : Harel_1991_J.Mol.Biol_221_909 |
| PubMedID: 1942036 |
| Title : Structural Studies on Acetylcholinesterase from Torpedo californica - |
| Author(s) : Sussman JL , Harel M , Frolow F , Oefner C , Toker L , Silman I |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :7 , 1991 |
| PubMedID: |
| Title : Poster: Physicochemical and crystallographic studies on the stability and structure of aged and nonaged organophosphoryl conjugates of chymotrypsin - |
| Author(s) : Su CT , Steinberg N , Silman I , Harel M , Sussman JL , Grunwald J , Ashani Y |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :274 , 1991 |
| PubMedID: |
| Title : Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein - Sussman_1991_Science_253_872 |
| Author(s) : Sussman JL , Harel M , Frolow F , Oefner C , Goldman A , Toker L , Silman I |
| Ref : Science , 253 :872 , 1991 |
| Abstract : Sussman_1991_Science_253_872 |
| ESTHER : Sussman_1991_Science_253_872 |
| PubMedSearch : Sussman_1991_Science_253_872 |
| PubMedID: 1678899 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase C - Sussman_1988_J.Mol.Biol_203_821 |
| Author(s) : Sussman JL , Harel M , Frolow F , Varon L , Toker L , Futerman AH , Silman I |
| Ref : Journal of Molecular Biology , 203 :821 , 1988 |
| Abstract : Sussman_1988_J.Mol.Biol_203_821 |
| ESTHER : Sussman_1988_J.Mol.Biol_203_821 |
| PubMedSearch : Sussman_1988_J.Mol.Biol_203_821 |
| PubMedID: 2850366 |