Report for Harden TK

General

Full name :

First name :

Mail :

Zip Code :

City :

Country :

Email :

Phone :

Fax :

Website :

Directory :

References (34)

Title : Galpha12\/13- and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors - Hains_2006_Mol.Pharmacol_69_2068
Author(s) : Hains MD , Wing MR , Maddileti S , Siderovski DP , Harden TK
Ref : Molecular Pharmacology , 69 :2068 , 2006
Abstract : Hains_2006_Mol.Pharmacol_69_2068
ESTHER : Hains_2006_Mol.Pharmacol_69_2068
PubMedSearch : Hains_2006_Mol.Pharmacol_69_2068
PubMedID: 16554409

Title : C(8)-substituted 1-azabicyclo[3.3.1]non-3-enes: a novel scaffold for muscarinic receptor ligands - Kim_2004_Bioorg.Med.Chem_12_2357
Author(s) : Kim MG , Bodor ET , Harden TK , Kohn H
Ref : Bioorganic & Medicinal Chemistry , 12 :2357 , 2004
Abstract : Kim_2004_Bioorg.Med.Chem_12_2357
ESTHER : Kim_2004_Bioorg.Med.Chem_12_2357
PubMedSearch : Kim_2004_Bioorg.Med.Chem_12_2357
PubMedID: 15080933

Title : C(8) substituted 1-azabicyclo[3.3.1]non-3-enes and C(8) substituted 1-azabicyclo[3.3.1]nonan-4-ones: novel muscarinic receptor antagonists - Kim_2003_J.Med.Chem_46_2216
Author(s) : Kim MG , Bodor ET , Wang C , Harden TK , Kohn H
Ref : Journal of Medicinal Chemistry , 46 :2216 , 2003
Abstract : Kim_2003_J.Med.Chem_46_2216
ESTHER : Kim_2003_J.Med.Chem_46_2216
PubMedSearch : Kim_2003_J.Med.Chem_46_2216
PubMedID: 12747793

Title : RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity - Hooks_2003_J.Biol.Chem_278_10087
Author(s) : Hooks SB , Waldo GL , Corbitt J , Bodor ET , Krumins AM , Harden TK
Ref : Journal of Biological Chemistry , 278 :10087 , 2003
Abstract : Hooks_2003_J.Biol.Chem_278_10087
ESTHER : Hooks_2003_J.Biol.Chem_278_10087
PubMedSearch : Hooks_2003_J.Biol.Chem_278_10087
PubMedID: 12531899

Title : Lack of nucleotide-promoted second messenger signaling responses in 1321N1 cells expressing the proposed P2Y receptor, p2y7 - Herold_1997_Biochem.Biophys.Res.Commun_235_717
Author(s) : Herold CL , Li Q , Schachter JB , Harden TK , Nicholas RA
Ref : Biochemical & Biophysical Research Communications , 235 :717 , 1997
Abstract : Herold_1997_Biochem.Biophys.Res.Commun_235_717
ESTHER : Herold_1997_Biochem.Biophys.Res.Commun_235_717
PubMedSearch : Herold_1997_Biochem.Biophys.Res.Commun_235_717
PubMedID: 9207227

Title : A guanine nucleotide-independent inwardly rectifying cation permeability is associated with P2Y1 receptor expression in Xenopus oocytes - O'Grady_1996_J.Biol.Chem_271_29080
Author(s) : O'Grady SM , Elmquist E , Filtz TM , Nicholas RA , Harden TK
Ref : Journal of Biological Chemistry , 271 :29080 , 1996
Abstract : O'Grady_1996_J.Biol.Chem_271_29080
ESTHER : O'Grady_1996_J.Biol.Chem_271_29080
PubMedSearch : O'Grady_1996_J.Biol.Chem_271_29080
PubMedID: 8910562

Title : Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase - Boyer_1993_J.Pharmacol.Exp.Ther_267_1140
Author(s) : Boyer JL , Lazarowski ER , Chen XH , Harden TK
Ref : Journal of Pharmacology & Experimental Therapeutics , 267 :1140 , 1993
Abstract : Boyer_1993_J.Pharmacol.Exp.Ther_267_1140
ESTHER : Boyer_1993_J.Pharmacol.Exp.Ther_267_1140
PubMedSearch : Boyer_1993_J.Pharmacol.Exp.Ther_267_1140
PubMedID: 8263774

Title : Regulation of inositol trisphosphate accumulation by muscarinic cholinergic and H1-histamine receptors on human astrocytoma cells. Differential induction of desensitization by agonists - Nakahata_1987_Biochem.J_241_337
Author(s) : Nakahata N , Harden TK
Ref : Biochemical Journal , 241 :337 , 1987
Abstract : Nakahata_1987_Biochem.J_241_337
ESTHER : Nakahata_1987_Biochem.J_241_337
PubMedSearch : Nakahata_1987_Biochem.J_241_337
PubMedID: 3593197

Title : Evidence that muscarinic cholinergic receptors selectively interact with either the cyclic AMP or the inositol phosphate second-messenger response systems - Hepler_1987_Biochem.J_247_793
Author(s) : Hepler JR , Hughes AR , Harden TK
Ref : Biochemical Journal , 247 :793 , 1987
Abstract : Hepler_1987_Biochem.J_247_793
ESTHER : Hepler_1987_Biochem.J_247_793
PubMedSearch : Hepler_1987_Biochem.J_247_793
PubMedID: 2827638

Title : [3H]propylbenzilylcholine mustard-labeling of muscarinic cholinergic receptors that selectively couple to phospholipase C or adenylate cyclase in two cultured cell lines - Liang_1987_Mol.Pharmacol_32_443
Author(s) : Liang M , Martin MW , Harden TK
Ref : Molecular Pharmacology , 32 :443 , 1987
Abstract : Liang_1987_Mol.Pharmacol_32_443
ESTHER : Liang_1987_Mol.Pharmacol_32_443
PubMedSearch : Liang_1987_Mol.Pharmacol_32_443
PubMedID: 3118180

Title : H1-histamine receptors on human astrocytoma cells - Nakahata_1986_Mol.Pharmacol_29_188
Author(s) : Nakahata N , Martin MW , Hughes AR , Hepler JR , Harden TK
Ref : Molecular Pharmacology , 29 :188 , 1986
Abstract : Nakahata_1986_Mol.Pharmacol_29_188
ESTHER : Nakahata_1986_Mol.Pharmacol_29_188
PubMedSearch : Nakahata_1986_Mol.Pharmacol_29_188
PubMedID: 2419744

Title : Identification of the phosphodiesterase regulated by muscarinic cholinergic receptors of 1321N1 human astrocytoma cells - Tanner_1986_Mol.Pharmacol_29_455
Author(s) : Tanner LI , Harden TK , Wells JN , Martin MW
Ref : Molecular Pharmacology , 29 :455 , 1986
Abstract : Tanner_1986_Mol.Pharmacol_29_455
ESTHER : Tanner_1986_Mol.Pharmacol_29_455
PubMedSearch : Tanner_1986_Mol.Pharmacol_29_455
PubMedID: 2422535

Title : Receptor reserve in the calcium-dependent cyclic AMP response of astrocytoma cells to muscarinic receptor stimulation: demonstration by agonist-induced desensitization, receptor inactivation, and phorbol ester treatment - Harden_1986_Mol.Pharmacol_30_200
Author(s) : Harden TK , Heng MM , Brown JH
Ref : Molecular Pharmacology , 30 :200 , 1986
Abstract : Harden_1986_Mol.Pharmacol_30_200
ESTHER : Harden_1986_Mol.Pharmacol_30_200
PubMedSearch : Harden_1986_Mol.Pharmacol_30_200
PubMedID: 3018476

Title : Guanine nucleotide-dependent pertussis-toxin-insensitive stimulation of inositol phosphate formation by carbachol in a membrane preparation from human astrocytoma cells - Hepler_1986_Biochem.J_239_141
Author(s) : Hepler JR , Harden TK
Ref : Biochemical Journal , 239 :141 , 1986
Abstract : Hepler_1986_Biochem.J_239_141
ESTHER : Hepler_1986_Biochem.J_239_141
PubMedSearch : Hepler_1986_Biochem.J_239_141
PubMedID: 3800973

Title : Characteristics of two biochemical responses to stimulation of muscarinic cholinergic receptors -
Author(s) : Harden TK , Tanner LI , Martin MW , Nakahata N , Hughes AR , Hepler JR , Evans T , Masters SB , Brown JH
Ref : Trends in Pharmacological Sciences , Suppl :14 , 1986
PubMedID:

Title : Adenosine and muscarinic cholinergic receptors attenuate cyclic AMP accumulation by different mechanisms in 1321N1 astrocytoma cells - Hughes_1986_J.Pharmacol.Exp.Ther_237_173
Author(s) : Hughes AR , Harden TK
Ref : Journal of Pharmacology & Experimental Therapeutics , 237 :173 , 1986
Abstract : Hughes_1986_J.Pharmacol.Exp.Ther_237_173
ESTHER : Hughes_1986_J.Pharmacol.Exp.Ther_237_173
PubMedSearch : Hughes_1986_J.Pharmacol.Exp.Ther_237_173
PubMedID: 2420967

Title : Muscarinic cholinergic receptor-mediated attenuation of adenylate cyclase activity in rat heart membranes - Smith_1985_J.Cyclic.Nucleotide.Protein.Phosphor.Res_10_197
Author(s) : Smith MM , Harden TK
Ref : J Cyclic Nucleotide Protein Phosphor Res , 10 :197 , 1985
Abstract : Smith_1985_J.Cyclic.Nucleotide.Protein.Phosphor.Res_10_197
ESTHER : Smith_1985_J.Cyclic.Nucleotide.Protein.Phosphor.Res_10_197
PubMedSearch : Smith_1985_J.Cyclic.Nucleotide.Protein.Phosphor.Res_10_197
PubMedID: 3998232

Title : Guanine nucleotide regulation of agonist binding to muscarinic cholinergic receptors. Relation to efficacy of agonists for stimulation of phosphoinositide breakdown and Ca2+ mobilization - Evans_1985_Biochem.J_232_751
Author(s) : Evans T , Hepler JR , Masters SB , Brown JH , Harden TK
Ref : Biochemical Journal , 232 :751 , 1985
Abstract : Evans_1985_Biochem.J_232_751
ESTHER : Evans_1985_Biochem.J_232_751
PubMedSearch : Evans_1985_Biochem.J_232_751
PubMedID: 3004418

Title : Guanine nucleotide-sensitive, high affinity binding of carbachol to muscarinic cholinergic receptors of 1321N1 astrocytoma cells is insensitive to pertussis toxin - Evans_1985_Mol.Pharmacol_27_32
Author(s) : Evans T , Martin MW , Hughes AR , Harden TK
Ref : Molecular Pharmacology , 27 :32 , 1985
Abstract : Evans_1985_Mol.Pharmacol_27_32
ESTHER : Evans_1985_Mol.Pharmacol_27_32
PubMedSearch : Evans_1985_Mol.Pharmacol_27_32
PubMedID: 2981400

Title : Regulation of cyclic AMP metabolism by muscarinic cholinergic receptors - Harden_1985_Adv.Cyclic.Nucleotide.Protein.Phosphorylation.Res_19_207
Author(s) : Harden TK , Evans T , Hepler JR , Hughes AR , Martin MW , Meeker RB , Smith MM , Tanner LI
Ref : Adv Cyclic Nucleotide Protein Phosphorylation Res , 19 :207 , 1985
Abstract : Harden_1985_Adv.Cyclic.Nucleotide.Protein.Phosphorylation.Res_19_207
ESTHER : Harden_1985_Adv.Cyclic.Nucleotide.Protein.Phosphorylation.Res_19_207
PubMedSearch : Harden_1985_Adv.Cyclic.Nucleotide.Protein.Phosphorylation.Res_19_207
PubMedID: 2988297

Title : Agonist-induced alteration in the membrane form of muscarinic cholinergic receptors - Harden_1985_J.Biol.Chem_260_13060
Author(s) : Harden TK , Petch LA , Traynelis SF , Waldo GL
Ref : Journal of Biological Chemistry , 260 :13060 , 1985
Abstract : Harden_1985_J.Biol.Chem_260_13060
ESTHER : Harden_1985_J.Biol.Chem_260_13060
PubMedSearch : Harden_1985_J.Biol.Chem_260_13060
PubMedID: 4055732

Title : Further evidence that muscarinic cholinergic receptors of 1321N1 astrocytoma cells couple to a guanine nucleotide regulatory protein that is not Ni - Martin_1985_Biochem.J_229_539
Author(s) : Martin MW , Evans T , Harden TK
Ref : Biochemical Journal , 229 :539 , 1985
Abstract : Martin_1985_Biochem.J_229_539
ESTHER : Martin_1985_Biochem.J_229_539
PubMedSearch : Martin_1985_Biochem.J_229_539
PubMedID: 3929772

Title : Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization - Masters_1985_Biochem.J_227_933
Author(s) : Masters SB , Martin MW , Harden TK , Brown JH
Ref : Biochemical Journal , 227 :933 , 1985
Abstract : Masters_1985_Biochem.J_227_933
ESTHER : Masters_1985_Biochem.J_227_933
PubMedSearch : Masters_1985_Biochem.J_227_933
PubMedID: 2988509

Title : Modification of receptor-mediated inhibition of adenylate cyclase in NG108-15 neuroblastoma X glioma cells by n-ethylmaleimide - Smith_1984_J.Pharmacol.Exp.Ther_228_425
Author(s) : Smith MM , Harden TK
Ref : Journal of Pharmacology & Experimental Therapeutics , 228 :425 , 1984
Abstract : Smith_1984_J.Pharmacol.Exp.Ther_228_425
ESTHER : Smith_1984_J.Pharmacol.Exp.Ther_228_425
PubMedSearch : Smith_1984_J.Pharmacol.Exp.Ther_228_425
PubMedID: 6319678

Title : Muscarinic cholinergic receptors of two cell lines that regulate cyclic AMP metabolism by different molecular mechanisms - Evans_1984_Mol.Pharmacol_26_395
Author(s) : Evans T , Smith MM , Tanner LI , Harden TK
Ref : Molecular Pharmacology , 26 :395 , 1984
Abstract : Evans_1984_Mol.Pharmacol_26_395
ESTHER : Evans_1984_Mol.Pharmacol_26_395
PubMedSearch : Evans_1984_Mol.Pharmacol_26_395
PubMedID: 6092892

Title : Modulation of muscarinic cholinergic receptor affinity for antagonists in rat heart - Martin_1984_J.Pharmacol.Exp.Ther_230_424
Author(s) : Martin MW , Smith MM , Harden TK
Ref : Journal of Pharmacology & Experimental Therapeutics , 230 :424 , 1984
Abstract : Martin_1984_J.Pharmacol.Exp.Ther_230_424
ESTHER : Martin_1984_J.Pharmacol.Exp.Ther_230_424
PubMedSearch : Martin_1984_J.Pharmacol.Exp.Ther_230_424
PubMedID: 6379149

Title : Relationships between phosphoinositide and calcium responses to muscarinic agonists in astrocytoma cells - Masters_1984_Mol.Pharmacol_26_149
Author(s) : Masters SB , Harden TK , Brown JH
Ref : Molecular Pharmacology , 26 :149 , 1984
Abstract : Masters_1984_Mol.Pharmacol_26_149
ESTHER : Masters_1984_Mol.Pharmacol_26_149
PubMedSearch : Masters_1984_Mol.Pharmacol_26_149
PubMedID: 6090879

Title : Pertussis toxin differentiates between two mechanisms of attenuation of cyclic AMP accumulation by muscarinic cholinergic receptors - Hughes_1984_Proc.Natl.Acad.Sci.U.S.A_81_5680
Author(s) : Hughes AR , Martin MW , Harden TK
Ref : Proc Natl Acad Sci U S A , 81 :5680 , 1984
Abstract : Hughes_1984_Proc.Natl.Acad.Sci.U.S.A_81_5680
ESTHER : Hughes_1984_Proc.Natl.Acad.Sci.U.S.A_81_5680
PubMedSearch : Hughes_1984_Proc.Natl.Acad.Sci.U.S.A_81_5680
PubMedID: 6091103

Title : Interaction of a radiolabeled agonist with cardiac muscarinic cholinergic receptors - Harden_1983_J.Pharmacol.Exp.Ther_227_570
Author(s) : Harden TK , Meeker RB , Martin MW
Ref : Journal of Pharmacology & Experimental Therapeutics , 227 :570 , 1983
Abstract : Harden_1983_J.Pharmacol.Exp.Ther_227_570
ESTHER : Harden_1983_J.Pharmacol.Exp.Ther_227_570
PubMedSearch : Harden_1983_J.Pharmacol.Exp.Ther_227_570
PubMedID: 6317839

Title : N-Ethylmaleimide-induced alteration in the interaction of agonists with muscarinic cholinergic receptors of rat brain -
Author(s) : Korn SJ , Martin MW , Harden TK
Ref : Journal of Pharmacology & Experimental Therapeutics , 224 :118 , 1983
PubMedID: 6294274

Title : Characterization of an altered membrane form of the beta-adrenergic receptor produced during agonist-induced desensitization - Waldo_1983_J.Biol.Chem_258_13900
Author(s) : Waldo GL , Northup JK , Perkins JP , Harden TK
Ref : Journal of Biological Chemistry , 258 :13900 , 1983
Abstract : Waldo_1983_J.Biol.Chem_258_13900
ESTHER : Waldo_1983_J.Biol.Chem_258_13900
PubMedSearch : Waldo_1983_J.Biol.Chem_258_13900
PubMedID: 6315711

Title : Muscarinic cholinergic receptor-mediated control of cyclic AMP metabolism. Agonist-induced changes in nucleotide synthesis and degradation - Meeker_1983_Mol.Pharmacol_23_384
Author(s) : Meeker RB , Harden TK
Ref : Molecular Pharmacology , 23 :384 , 1983
Abstract : Meeker_1983_Mol.Pharmacol_23_384
ESTHER : Meeker_1983_Mol.Pharmacol_23_384
PubMedSearch : Meeker_1983_Mol.Pharmacol_23_384
PubMedID: 6300648

Title : Differential modification of the interaction of cardiac muscarinic cholinergic and beta-adrenergic receptors with a guanine nucleotide binding component(s) -
Author(s) : Harden TK , Scheer AG , Smith MM
Ref : Molecular Pharmacology , 21 :570 , 1982
PubMedID: 6287196

Title : Muscarinic cholinergic receptor-mediated activation of phosphodiesterase -
Author(s) : Meeker RB , Harden TK
Ref : Molecular Pharmacology , 22 :310 , 1982
PubMedID: 6183568